The metabolism of 4-trifluoromethoxyaniline and [13C]-4-trifluoromethoxyacetanilide in the rat: detection and identification of metabolites excreted in the urine by NMR and HPLC-NMR.
暂无分享,去创建一个
I. Wilson | M. Hofmann | M. Spraul | J. Lindon | J. Nicholson | E. Lenz | M. Tugnait | P. Phillips
[1] I. Wilson,et al. Identification of the urinary metabolites of 4-bromoaniline and 4-bromo- [carbonyl - 13 C]-acetanilide in rat , 2002, Xenobiotica; the fate of foreign compounds in biological systems.
[2] I. Wilson,et al. Directly-coupled HPLC-NMR spectroscopic studies of metabolism and futile deacetylation of phenacetin in the rat. , 1999, Journal of pharmaceutical and biomedical analysis.
[3] I. Wilson,et al. NMR spectroscopic studies on the metabolism and futile deacetylation of phenacetin in the rat. , 1997, Xenobiotica; the fate of foreign compounds in biological systems.
[4] I. Wilson,et al. High resolution NMR spectroscopic studies on the metabolism and futile deacetylation of 4-hydroxyacetanilide (paracetamol) in the rat. , 1995, Biochemical pharmacology.
[5] J. Vervoort,et al. Study on the regioselectivity and mechanism of the aromatic hydroxylation of monofluoroanilines. , 1992, Chemico-biological interactions.
[6] I. Wilson,et al. Species differences in the metabolism of 14C-p-trifluoromethylaniline: production of an oxanilic acid as the major metabolite by the rat. , 1985, Biochemical pharmacology.
[7] W. Lenk,et al. Metabolites of 4-chloroaniline and chloroacetanilides produced by rabbits and pigs. , 1971, Biochemical pharmacology.
[8] W. Lenk,et al. Oxidation of acetanilides to glycolanilides and oxanilic acids in rabbits. , 1969, Biochemical pharmacology.
[9] E. Boyland,et al. The biochemistry of aromatic amines. 10. Enzymic N-hydroxylation of arylamines and conversion of arylhydroxylamines into o-aminophenols. , 1964, The Biochemical journal.
[10] I. Wilson,et al. Studies on the metabolism of 4-fluoroaniline and 4-fluoroacetanilide in rat: formation of 4-acetamidophenol (paracetamol) and its metabolites via defluorination and N-acetylation. , 1999, Xenobiotica; the fate of foreign compounds in biological systems.