Genomic distribution of quantitative trait loci for yield and yield-related traits in common wheat.

A major objective of quantitative trait locus (QTL) studies is to find genes/markers that can be used in breeding programs via marker assisted selection (MAS). We surveyed the QTLs for yield and yield-related traits and their genomic distributions in common wheat (Triticum aestivum L.) in the available published reports. We then carried out a meta-QTL (MQTL) analysis to identify the major and consistent QTLs for these traits. In total, 55 MQTLs were identified, of which 12 significant MQTLs were located on wheat chromosomes 1A, 1B, 2A, 2D, 3B, 4A, 4B, 4D and 5A. Our study showed that the genetic control of yield and its components in common wheat involved the important genes such as Rht and Vrn. Furthermore, several significant MQTLs were found in the chromosomal regions corresponding to several rice genomic locations containing important QTLs for yield related traits. Our results demonstrate that meta-QTL analysis is a powerful tool for confirming the major and stable QTLs and refining their chromosomal positions in common wheat, which may be useful for improving the MAS efficiency of yield related traits.

[1]  Zheng You-liang,et al.  Mapping QTLs for pre-harvest sprouting tolerance on chromosome 2D in a synthetic hexaploid wheat×common wheat cross , 2010, Journal of Applied Genetics.

[2]  I. Bancroft,et al.  Unraveling the Complex Trait of Crop Yield With Quantitative Trait Loci Mapping in Brassica napus , 2009, Genetics.

[3]  D. Laurie,et al.  Meta-QTL analysis of the genetic control of ear emergence in elite European winter wheat germplasm , 2009, Theoretical and Applied Genetics.

[4]  Tian Ji-chun,et al.  QTL mapping for grain yield and spike related traits in common wheat. , 2009 .

[5]  L. Hartl,et al.  A major QTL for resistance against Fusarium head blight in European winter wheat , 2009, Theoretical and Applied Genetics.

[6]  A. Abbott,et al.  Quantitative trait loci meta-analysis of Plum pox virus resistance in apricot (Prunus armeniaca L.): new insights on the organization and the identification of genomic resistance factors. , 2009, Molecular plant pathology.

[7]  Guorong Zhang,et al.  Genetic Relationship and QTL Association between Kernel Shattering and Agronomic Traits in Wheat , 2009 .

[8]  Ruixia Wang.  QTL Mapping for Grain Filling Rate and Thousand-Grain Weight in Different Ecological Environments in Wheat: QTL Mapping for Grain Filling Rate and Thousand-Grain Weight in Different Ecological Environments in Wheat , 2009 .

[9]  Lixin Wang,et al.  Association mapping of agronomic traits on chromosome 2A of wheat , 2009, Genetica.

[10]  Liang Zhao,et al.  Detection of quantitative trait loci for heading date based on the doubled haploid progeny of two elite Chinese wheat cultivars , 2009, Genetica.

[11]  F. Kong,et al.  QTL analysis of kernel shape and weight using recombinant inbred lines in wheat , 2009, Euphytica.

[12]  T. Miedaner,et al.  Revealing the genetic architecture of FHB resistance in hexaploid wheat (Triticum aestivum L.) by QTL meta-analysis , 2009, Molecular Breeding.

[13]  Kunming Zhang.  QTL Mapping for Adult-Plant Resistance to Powdery Mildew, Lodging Resistance and Internode Length below Spike in Wheat: QTL Mapping for Adult-Plant Resistance to Powdery Mildew, Lodging Resistance and Internode Length below Spike in Wheat , 2008 .

[14]  Z. Ren,et al.  Mining Favorable Alleles of QTLs Conferring Thousand-Grain Weight from Synthetic Wheat , 2008 .

[15]  W. R. Whalley,et al.  A bioinformatic and transcriptomic approach to identifying positional candidate genes without fine mapping: an example using rice root-growth QTLs. , 2008, Genomics.

[16]  S. Chao,et al.  QTL analysis of pasta quality using a composite microsatellite and SNP map of durum wheat , 2008, Theoretical and Applied Genetics.

[17]  W. Friedt,et al.  Genomic regions for yield and yield parameters in Chinese winter wheat (Triticum aestivum L.) genotypes tested under varying environments correspond to QTL in widely different wheat materials , 2008 .

[18]  Ky L. Mathews,et al.  Multi-environment QTL mixed models for drought stress adaptation in wheat , 2008, Theoretical and Applied Genetics.

[19]  Ji-chun Tian,et al.  QTL Mapping for Adult-Plant Resistance to Powdery Mildew, Lodging Resistance, and Internode Length Below Spike in Wheat , 2008 .

[20]  Brigitte Courtois,et al.  A genome-wide meta-analysis of rice blast resistance genes and quantitative trait loci provides new insights into partial and complete resistance. , 2008, Molecular plant-microbe interactions : MPMI.

[21]  P. D. Brown,et al.  Molecular mapping of quantitative trait loci for yield and yield components in spring wheat (Triticum aestivum L.) , 2008, Theoretical and Applied Genetics.

[22]  T. Friesen,et al.  Whole genome mapping in a wheat doubled haploid population using SSRs and TRAPs and the identification of QTL for agronomic traits , 2008, Molecular Breeding.

[23]  C. Royo,et al.  Quantitative Trait Loci for Grain Yield and Adaptation of Durum Wheat (Triticum durum Desf.) Across a Wide Range of Water Availability , 2008, Genetics.

[24]  W. Rui.  QTL Mapping for Grain Filling Rate and Thousand-Grain Weight in Different Ecological Environments in Wheat , 2008 .

[25]  Jia Ji-zeng.  Mapping of Large-Spike and Much-Kernel QTL by Using a Synthetic Wheat Am3 as Donor , 2008 .

[26]  W. Hui.  QTL Mapping for Kernel Weight Using GW3-1 and IND109 Markers in Common Wheat(Triticum aestivum L.) , 2008 .

[27]  L. Hai,et al.  QTL mapping for grain filling rate and yield-related traits in RILs of the Chinese winter wheat population Heshangmai × Yu8679 , 2008, Theoretical and Applied Genetics.

[28]  A. Börner,et al.  Fine mapping of the region on wheat chromosome 7D controlling grain weight , 2008, Functional & Integrative Genomics.

[29]  P. Langridge,et al.  Genetic dissection of grain yield in bread wheat. I. QTL analysis , 2007, Theoretical and Applied Genetics.

[30]  P. Langridge,et al.  Genetic dissection of grain yield in bread wheat. II. QTL-by-environment interaction , 2007, Theoretical and Applied Genetics.

[31]  Xavier Draye,et al.  Meta-analysis of Polyploid Cotton QTL Shows Unequal Contributions of Subgenomes to a Complex Network of Genes and Gene Clusters Implicated in Lint Fiber Development , 2007, Genetics.

[32]  J. Léon,et al.  AB-QTL analysis in winter wheat: I. Synthetic hexaploid wheat (T. turgidum ssp. dicoccoides  × T. tauschii) as a source of favourable alleles for milling and baking quality traits , 2007, Theoretical and Applied Genetics.

[33]  M. Lemmens,et al.  Identification of QTLs for resistance to Fusarium head blight, DON accumulation and associated traits in the winter wheat variety Arina , 2007, Theoretical and Applied Genetics.

[34]  G. M. Paulsen,et al.  Markers associated with a QTL for grain yield in wheat under drought , 2007, Molecular Breeding.

[35]  Xinhua Zhao,et al.  A intervarietal genetic map and QTL analysis for yield traits in wheat , 2007, Molecular Breeding.

[36]  M. Sorrells,et al.  QTL analysis of kernel size and shape in two hexaploid wheat mapping populations , 2007 .

[37]  J. Snape,et al.  Dissecting gene × environmental effects on wheat yields via QTL and physiological analysis , 2007, Euphytica.

[38]  É. Hanocq,et al.  Most significant genome regions involved in the control of earliness traits in bread wheat, as revealed by QTL meta-analysis , 2007, Theoretical and Applied Genetics.

[39]  P. Kulwal,et al.  QTL mapping for yield and yield contributing traits in two mapping populations of bread wheat , 2007, Molecular Breeding.

[40]  Zheng Yong-lian,et al.  The comparative analysis based on maize integrated QTL map and meta-analysis of plant height QTLs , 2006 .

[41]  P. Gupta,et al.  QTL analysis for grain weight in common wheat , 2006, Euphytica.

[42]  A. Kamińska,et al.  Dissecting a wheat QTL for yield present in a range of environments: from the QTL to candidate genes. , 2006, Journal of experimental botany.

[43]  P. D. Brown,et al.  Molecular detection of QTLs for agronomic and quality traits in a doubled haploid population derived from two Canadian wheats (Triticum aestivum L.) , 2006, Theoretical and Applied Genetics.

[44]  P. S. Baenziger,et al.  High-density mapping and comparative analysis of agronomically important traits on wheat chromosome 3A. , 2006, Genomics.

[45]  Bin Han,et al.  GS3, a major QTL for grain length and weight and minor QTL for grain width and thickness in rice, encodes a putative transmembrane protein , 2006, Theoretical and Applied Genetics.

[46]  M. Sorrells,et al.  Association Mapping of Kernel Size and Milling Quality in Wheat (Triticum aestivum L.) Cultivars , 2006, Genetics.

[47]  Luo Wei-zhong.  Analysis of QTLs for Yield Traits of Wheat , 2006 .

[48]  S. Xue,et al.  Molecular genetic analysis of five spike-related traits in wheat using RIL and immortalized F2 populations , 2006, Molecular Genetics and Genomics.

[49]  B. Gill,et al.  Advanced backcross QTL analysis of a hard winter wheat × synthetic wheat population , 2006, Theoretical and Applied Genetics.

[50]  G. Bai,et al.  Quantitative trait loci for yield and related traits in the wheat population Ning7840 × Clark , 2006, Theoretical and Applied Genetics.

[51]  N. Ames,et al.  Mapping quantitative trait loci controlling agronomic traits in the spring wheat cross RL4452 × 'AC Domain' , 2005 .

[52]  Q. Qian,et al.  Cytokinin Oxidase Regulates Rice Grain Production , 2005, Science.

[53]  T. Friesen,et al.  A wheat intervarietal genetic linkage map based on microsatellite and target region amplified polymorphism markers and its utility for detecting quantitative trait loci , 2005, Theoretical and Applied Genetics.

[54]  J. Snape,et al.  Identification and characterization of quantitative trait loci related to lodging resistance and associated traits in bread wheat , 2005 .

[55]  Wang Hong-gang.  Effects of Chromosomes in D Genome from Aegliops tauschii on Wheat Yield Traits , 2005 .

[56]  C. Calestani,et al.  A high-density genetic map of hexaploid wheat (Triticum aestivum L.) from the cross Chinese Spring × SQ1 and its use to compare QTLs for grain yield across a range of environments , 2005, Theoretical and Applied Genetics.

[57]  Alain Charcosset,et al.  Genetic Architecture of Flowering Time in Maize As Inferred From Quantitative Trait Loci Meta-analysis and Synteny Conservation With the Rice Genome , 2004, Genetics.

[58]  Alain Charcosset,et al.  BioMercator: integrating genetic maps and QTL towards discovery of candidate genes , 2004, Bioinform..

[59]  K. Edwards,et al.  A high-density microsatellite consensus map for bread wheat (Triticum aestivum L.) , 2004, Theoretical and Applied Genetics.

[60]  M. Ganal,et al.  Advanced backcross QTL analysis in progenies derived from a cross between a German elite winter wheat variety and a synthetic wheat (Triticum aestivumL.) , 2004, Theoretical and Applied Genetics.

[61]  J. Tohme,et al.  QTL mapping of grain quality traits from the interspecific cross Oryza sativa × O. glaberrima , 2004, Theoretical and Applied Genetics.

[62]  M. Nachit,et al.  A genetic linkage map of the Durum × Triticum dicoccoides backcross population based on SSRs and AFLP markers, and QTL analysis for milling traits , 2004, Theoretical and Applied Genetics.

[63]  B. Keller,et al.  Identification of QTLs for BYDV tolerance in bread wheat , 2002, Euphytica.

[64]  Susan McCouch,et al.  RFLP mapping of isozymes, RAPD and QTLs for grain shape, brown planthopper resistance in a doubled haploid rice population , 2004, Molecular Breeding.

[65]  J. Snape,et al.  Genetical analysis of chromosome 5A of wheat and its influence on important agronomic characters , 1985, Theoretical and Applied Genetics.

[66]  Zhou Miao-ping.  Detection of QTLs for Plant Height in Wheat Using RILs , 2004 .

[67]  Marion S. Röder,et al.  Molecular marker analysis of kernel size and shape in bread wheat , 2003 .

[68]  A. Jahoor,et al.  Inheritance and localisation of resistance to Mycosphaerella graminicola causing septoria tritici blotch and plant height in the wheat (Triticum aestivum L.) genome with DNA markers , 2003, Theoretical and Applied Genetics.

[69]  Michael J. Thomson,et al.  Mapping quantitative trait loci for yield, yield components and morphological traits in an advanced backcross population between Oryza rufipogon and the Oryza sativa cultivar Jefferson , 2003, Theoretical and Applied Genetics.

[70]  E. Nevo,et al.  Domestication quantitative trait loci in Triticum dicoccoides, the progenitor of wheat , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[71]  M. Ganal,et al.  Advanced backcross QTL analysis for the identification of quantitative trait loci alleles from wild relatives of wheat (Triticum aestivum L.) , 2003, Theoretical and Applied Genetics.

[72]  P. Gupta,et al.  QTL mapping for growth and leaf characters in bread wheat , 2003 .

[73]  S. Nègre,et al.  Mapping of quantitative trait loci for field resistance to Fusarium head blight in an European winter wheat , 2003, Theoretical and Applied Genetics.

[74]  G. Charmet,et al.  Genetic analysis of grain protein-content, grain yield and thousand-kernel weight in bread wheat , 2003, Theoretical and Applied Genetics.

[75]  J. Snape,et al.  An update of the Courtot × Chinese Spring intervarietal molecular marker linkage map for the QTL detection of agronomic traits in wheat , 2003, Theoretical and Applied Genetics.

[76]  A. Börner,et al.  Mapping of quantitative trait loci determining agronomic important characters in hexaploid wheat (Triticum aestivum L.) , 2002, Theoretical and Applied Genetics.

[77]  Dongcheng Liu,et al.  Mapping quantitative trait loci for plant height in wheat (Triticum aestivum L.) using a F2:3 population. , 2002, Yi chuan xue bao = Acta genetica Sinica.

[78]  Xing Yong-zhong,et al.  Mapping Quantitative Trait Loci for Grain Appearance Traits of Rice Using a Recombinant Inbred Line Population , 2001 .

[79]  P. Ranjekar,et al.  Identification of inter simple sequence repeat (ISSR) markers associated with seed size in wheat , 2001, Theoretical and Applied Genetics.

[80]  H. Miura,et al.  Mapping QTLs controlling grain yield and its components on chromosome 5A of wheat , 2000, Theoretical and Applied Genetics.

[81]  Qifa Zhang,et al.  Genetic bases of appearance quality of rice grains in Shanyou 63, an elite rice hybrid , 2000, Theoretical and Applied Genetics.

[82]  H. Dhaliwal,et al.  Identification of eight chromosomes and a microsatellite marker on 1AS associated with QTL for grain weight in bread wheat , 2000, Theoretical and Applied Genetics.

[83]  B. Goffinet,et al.  Quantitative trait loci: a meta-analysis. , 2000, Genetics.

[84]  M. Shah,et al.  Molecular Mapping of Loci for Agronomic Traits on Chromosome 3A of Bread Wheat , 1999 .

[85]  P. Christou,et al.  ‘Green revolution’ genes encode mutant gibberellin response modulators , 1999, Nature.

[86]  H. Miura,et al.  Identification of genetic loci affecting amylose content and agronomic traits on chromosome 4A of wheat , 1999, Theoretical and Applied Genetics.

[87]  H. Miura,et al.  QTL mapping of genes controlling ear emergence time and plant height on chromosome 5A of wheat , 1999, Theoretical and Applied Genetics.

[88]  D. Mackill,et al.  Quantitative trait locus analysis for rice panicle and grain characteristics , 1998, Theoretical and Applied Genetics.

[89]  Cai-guo Xu,et al.  Importance of epistasis as the genetic basis of heterosis in an elite rice hybrid. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[90]  M. Soller,et al.  A Simple Method to Calculate Resolving Power and Confidence Interval of QTL Map Location , 1997, Behavior genetics.