When, and When Not, to Use Digoxin in the Elderly

[1]  E. J. Brown,et al.  The effect of digoxin on mortality and morbidity in patients with heart failure. , 1997, The New England journal of medicine.

[2]  W. Remme,et al.  Value of digoxin in heart failure and sinus rhythm: new features of an old drug? , 1996, Journal of the American College of Cardiology.

[3]  H. Crijns,et al.  Alteration of peripheral vasodilatory reserve capacity after cardioversion of atrial fibrillation. , 1996, European heart journal.

[4]  A. Camm,et al.  Atrial fibrillation: maintenance of sinus rhythm versus rate control. , 1996, The American journal of cardiology.

[5]  J. Haaksma,et al.  HEART-RATE-VARIABILITY IN PATIENTS WITH MILD-TO-MODERATE HEART-FAILURE - EFFECTS OF NEUROHORMONAL MODULATION BY DIGOXIN AND IBOPAMINE , 1995 .

[6]  M. Gheorghiade,et al.  Effects of increasing maintenance dose of digoxin on left ventricular function and neurohormones in patients with chronic heart failure treated with diuretics and angiotensin-converting enzyme inhibitors. , 1995, Circulation.

[7]  J. Brouwer,et al.  Progression of mild untreated heart failure purina six months follow-up and clinical and neurohumoral effects of ibopamine and digoxin as monotherapy , 1995 .

[8]  J. Bigger,et al.  Effect of long-term digoxin therapy on autonomic function in patients with chronic heart failure. , 1995, Journal of the American College of Cardiology.

[9]  Crijns,et al.  Functional capacity before and after cardioversion of atrial fibrillation: a controlled study. , 1994, British heart journal.

[10]  D. D. Bono Digoxin in eurhythmic heart failure: PROVED or "not proven"? , 1994, The Lancet.

[11]  M. Gheorghiade,et al.  WITHDRAWAL OF DIGOXIN FROM PATIENTS WITH CHRONIC HEART FAILURE TREATED WITH ANGIOTENSIN CONVERTING ENZYME INHIBITORS , 2010 .

[12]  M. Schumacher,et al.  Captopril versus digoxin in patients with coronary artery disease and mild heart failure. A prospective, double-blind, placebo-controlled multicenter study. The CADS Study Group. , 1993, Herz.

[13]  J. Brouwer,et al.  Double-blind placebo-controlled study of ibopamine and digoxin in patients with mild to moderate heart failure: results of the Dutch Ibopamine Multicenter Trial (DIMT). , 1993, Journal of the American College of Cardiology.

[14]  H. Crijns,et al.  Changes in left and right atrial size after cardioversion of atrial fibrillation: role of mitral valve disease. , 1993, Journal of the American College of Cardiology.

[15]  B. Uretsky,et al.  Randomized study assessing the effect of digoxin withdrawal in patients with mild to moderate chronic congestive heart failure: results of the PROVED trial. PROVED Investigative Group. , 1993, Journal of the American College of Cardiology.

[16]  H. Crijns,et al.  Chronotropic response to exercise in patients with atrial fibrillation: relation to functional state. , 1993, British heart journal.

[17]  J. Cohn,et al.  Plasma Norepinephrine, Plasma Renin Activity, and Congestive Heart Failure Relations to Survival and the Effects of Therapy in V‐HeFT II , 1993, Circulation.

[18]  M. Packer The neurohormonal hypothesis: a theory to explain the mechanism of disease progression in heart failure. , 1992, Journal of the American College of Cardiology.

[19]  R. Lewis Clinical use of serum digoxin concentrations. , 1992, The American journal of cardiology.

[20]  D. Ferguson Digitalis and neurohormonal abnormalities in heart failure and implications for therapy. , 1992, The American journal of cardiology.

[21]  M. Gheorghiade,et al.  Optimal heart rate control for patients with chronic atrial fibrillation: are pharmacologic choices truly changing? , 1992, American heart journal.

[22]  D. Ferguson,et al.  Digoxin. A neurohormonal modulator in heart failure? , 1991, Circulation.

[23]  E. Galun,et al.  Failure of long-term digitalization to prevent rapid ventricular response in patients with paroxysmal atrial fibrillation. , 1991, Chest.

[24]  R. Falk,et al.  Digoxin for atrial fibrillation: a drug whose time has gone? , 1991, Annals of internal medicine.

[25]  W. Aronow Digoxin or Angiotensin Converting Enzyme Inhibitors for Congestive Heart Failure in Geriatric Patients , 1991, Drugs & aging.

[26]  L. Rydén,et al.  Ventricular control and exercise performance in chronic atrial fibrillation: Effects of diltiazem verapamil☆ , 1990 .

[27]  J. Rawles,et al.  Time of occurrence, duration, and ventricular rate of paroxysmal atrial fibrillation: the effect of digoxin. , 1990, British heart journal.

[28]  G. Guyatt,et al.  To what extent do congestive heart failure patients in sinus rhythm benefit from digoxin therapy? A systematic overview and meta-analysis. , 1990, The American journal of medicine.

[29]  N. Sinha,et al.  Digoxin or verapamil or metoprolol for heart rate control in patients with mitral stenosis--a randomised cross-over study. , 1989, International journal of cardiology.

[30]  D. Ferguson,et al.  Sympathoinhibitory responses to digitalis glycosides in heart failure patients. Direct evidence from sympathetic neural recordings. , 1989, Circulation.

[31]  P. Blanchette,et al.  Diastolic dysfunction in elderly patients with congestive heart failure. , 1989, The American journal of cardiology.

[32]  R. Schlant,et al.  A comparison of oral milrinone, digoxin, and their combination in the treatment of patients with chronic heart failure. , 1989, The New England journal of medicine.

[33]  T. A. S. Group,et al.  DOUBLE-BLIND PLACEBO-CONTROLLED COMPARISON OF DIGOXIN AND XAMOTEROL IN CHRONIC HEART FAILURE , 1988, The Lancet.

[34]  T. Smith,et al.  Digitalis mechanisms of action and clinical use , 1988 .

[35]  M. Wilén,et al.  Comparative effects of therapy with captopril and digoxin in patients with mild to moderate heart failure. The Captopril-Digoxin Multicenter Research Group. , 1988, JAMA.

[36]  R. Falk,et al.  Digoxin for converting recent-onset atrial fibrillation to sinus rhythm. A randomized, double-blinded trial. , 1987, Annals of internal medicine.

[37]  T. Moreland,et al.  A comparison of verapamil and digoxin in the treatment of atrial fibrillation. , 1987, European heart journal.

[38]  Katz Am Potential deleterious effects of inotropic agents in the therapy of chronic heart failure. , 1986 .

[39]  U. Elkayam,et al.  Efficacy and safety of medium- and high-dose diltiazem alone and in combination with digoxin for control of heart rate at rest and during exercise in patients with chronic atrial fibrillation. , 1986, Circulation.

[40]  F. Marcus Pharmacokinetic interactions between digoxin and other drugs. , 1985, Journal of the American College of Cardiology.

[41]  A. M. Watanabe Digitalis and the autonomic nervous system. , 1985, Journal of the American College of Cardiology.

[42]  J. Ronan,et al.  Effects of nadolol on the spontaneous and exercise-provoked heart rate of patients with chronic atrial fibrillation receiving stable dosages of digoxin. , 1984, American heart journal.

[43]  R. Luchi,et al.  Effect of Digoxin on Ejection Fraction in Elderly Patients with Congestive Heart Failure , 1984, Journal of the American Geriatrics Society.

[44]  E. Kaplinsky,et al.  Superiority of oral verapamil therapy to digoxin in treatment of chronic atrial fibrillation. , 1983, Chest.

[45]  W. Kannel,et al.  Epidemiologic features of chronic atrial fibrillation: the Framingham study. , 1982, The New England journal of medicine.

[46]  A. Moss,et al.  Digitalis‐associated Cardiac Mortality After Myocardial Infarction , 1981, Circulation.

[47]  E. Kaplinsky,et al.  Inefficacy of digitalis in the control of heart rate in patients with chronic atrial fibrillation: beneficial effect of an added beta adrenergic blocking agent. , 1979, The American journal of cardiology.

[48]  T. D. Sellers,et al.  Digitalis in the Pre-excitation Syndrome: Analysis during Atrial Fibrillation , 1977, Circulation.

[49]  Sang Joon Park,et al.  Efficacy and safety ofdigoxin alone and in combination with low-dosediltiazem orbetaxolol to control ventricular rate in chronic atrial fibrillation , 1995 .

[50]  B. Uretsky,et al.  ON BEHALF OF THE PROVED INVESTIGATIVE GROUP. RANDOMIZED STUDY ASSESSING THE EFFECT OF DIGOXIN WITHDRAWAL IN PATIENTS WITH MILD TO MODERATE CHRONIC CONGESTIVE HEART FAILURE: RESULT OF PROVED TRIAL , 1993 .

[51]  E. Lakatta Changes in cardiovascular function with aging. , 1990, European heart journal.

[52]  M. Gheorghiade,et al.  Comparative hemodynamic and neurohormonal effects of intravenous captopril and digoxin and their combinations in patients with severe heart failure. , 1989, Journal of the American College of Cardiology.