Petroleum hydrocarbon toxicity studies. I. Methodology.

Abstract The objectives, protocols, and procedures followed in the study of the inhalation toxicity of a series of petroleum hydrocarbons are presented herein. To conserve journal space reference will be made to this report in order to avoid repetition in succeeding reports on selected commercially available petroleum hydrocarbons. The compounds are arranged in a matrix based on boiling range and aromaticity. It is hoped that the information gathered in this series of 12 or more studies will provide a basis for predicting the toxicity of closely related hydrocarbon mixtures that are articles of commerce.

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