Electrostatic Assembly of Platinum Nanoparticles along Electrospun Polymeric Nanofibers for High Performance Electrochemical Sensors

A novel polyacrylonitrile (PAN) nanofibrous membrane conjugated with platinum nanoparticles (PtNPs) was fabricated by electrospinning and electrostatic assembly techniques. In this procedure, PAN was electrospun with 3-aminopropyltriethoxysilane (APS) together as precursor materials. First, amine groups were introduced onto PAN nanofibers, and then the as-prepared negative-charged platinum nanoparticles (PtNPs) were conjugated onto the surface of the amino-modified PAN nanofibers uniformly by the electrostatic interaction-mediated assembly. The fabricated PAN–PtNPs hybrid nanofibrous membrane was further utilized to modify the glassy carbon electrodes and was used for the fabrication of a non-enzymatic amperometric sensor to detect hydrogen peroxide (H2O2). The electrochemical results indicated that, due to the uniform dispersion of PtNPs and the electrostatic interaction between amine groups and PtNPs, the fabricated PAN–PtNPs nanofibrous membrane-based electrochemical sensor showed excellent electrocatalytic activity toward H2O2, and the chronoamperometry measurements illustrated that the fabricated sensor had a high sensitivity for detecting H2O2. It is anticipated that the strategies used in this work will not only guide the design and fabrication of functional polymeric nanofiber-based biomaterials and nanodevices, but also extend their potential applications in energy storage, cytology, and tissue engineering.

[1]  Shu-Hong Yu,et al.  Nanoparticles meet electrospinning: recent advances and future prospects. , 2014, Chemical Society reviews.

[2]  Y. Wang,et al.  Shape-Selective Preparation and Properties of Oxalate-Stabilized Pt Colloid , 2002 .

[3]  D. Cliffel,et al.  Electrochemical sensors and biosensors. , 2012, Analytical chemistry.

[4]  Yu Zhou,et al.  A single mesoporous ZnO/Chitosan hybrid nanostructure for a novel free nanoprobe type biosensor. , 2013, Biosensors & bioelectronics.

[5]  Zhiqiang Su,et al.  Electrospun doping of carbon nanotubes and platinum nanoparticles into the β-phase polyvinylidene difluoride nanofibrous membrane for biosensor and catalysis applications. , 2014, ACS applied materials & interfaces.

[6]  Tomoya Uruga,et al.  Bioreductive deposition of platinum nanoparticles on the bacterium Shewanella algae. , 2007, Journal of biotechnology.

[7]  P. Solanki,et al.  Nanostructured metal oxide-based biosensors , 2011 .

[8]  Zhiqiang Su,et al.  Nanoscale Graphene Doped with Highly Dispersed Silver Nanoparticles: Quick Synthesis, Facile Fabrication of 3D Membrane‐Modified Electrode, and Super Performance for Electrochemical Sensing , 2016 .

[9]  Zhiqiang Su,et al.  Fabrication of Multiwalled Carbon Nanotube/Polypropylene Conductive Fibrous Membranes by Melt Electrospinning , 2014 .

[10]  Gang Wei,et al.  Fabrication, characterization and sensor application of electrospun polyurethane nanofibers filled with carbon nanotubes and silver nanoparticles. , 2013, Journal of materials chemistry. B.

[11]  Rajesh Kumar,et al.  Surface modification of inorganic nanoparticles for development of organic–inorganic nanocomposites—A review , 2013 .

[12]  Kezhi Zheng,et al.  Luminescent CePO₄:Tb colloids for H₂O₂ and glucose sensing. , 2014, The Analyst.

[13]  Shih‐Yuan Lu,et al.  Porous fluorine-doped tin oxide as a promising substrate for electrochemical biosensors-demonstration in hydrogen peroxide sensing. , 2014, Journal of materials chemistry. B.

[14]  Zhiqiang Su,et al.  Electrospinning: a facile technique for fabricating polymeric nanofibers doped with carbon nanotubes and metallic nanoparticles for sensor applications , 2014 .

[15]  Seeram Ramakrishna,et al.  Preparation of Core−Shell Structured PCL-r-Gelatin Bi-Component Nanofibers by Coaxial Electrospinning , 2004 .

[16]  Y. Miao,et al.  A novel hydrogen peroxide sensor based on Ag/SnO2 composite nanotubes by electrospinning , 2013 .

[17]  Guonan Chen,et al.  A sensitive fluorescence biosensor for alkaline phosphatase activity based on the Cu(II)-dependent DNAzyme. , 2016, Analytica chimica acta.

[18]  Zhiqiang Su,et al.  Nanoporous Carbon Nanofibers Decorated with Platinum Nanoparticles for Non-Enzymatic Electrochemical Sensing of H2O2 , 2015, Nanomaterials.

[19]  Kezhi Zheng,et al.  Luminescent CePO 4 :Tb colloids for H 2 O 2 and glucose sensing† , 2014 .

[20]  Gang Wei,et al.  Hydrothermal synthesis of zinc oxide-reduced graphene oxide nanocomposites for an electrochemical hydrazine sensor , 2015 .

[21]  Chunzhong Li,et al.  Gold-coated silica-fiber hybrid materials for application in a novel hydrogen peroxide biosensor. , 2012, Biosensors & bioelectronics.

[22]  Ping Wang,et al.  Enabling multi-enzyme biocatalysis using coaxial-electrospun hollow nanofibers: redesign of artificial cells. , 2014, Journal of materials chemistry. B.

[23]  A. Baeumner,et al.  Recent progress in the design of nanofiber-based biosensing devices. , 2012, Lab on a chip.

[24]  Fan Gao,et al.  Vertically aligned Pt nanowire array/Au nanoparticle hybrid structure as highly sensitive amperometric biosensors , 2017 .

[25]  R. Jana,et al.  In Situ Formation of Nanohybrid Shish-Kebabs during Electrospinning for the Creation of Hierarchical Shish-Kebab Structures , 2016 .

[26]  Zhiqiang Su,et al.  Electrospinning design of functional nanostructures for biosensor applications. , 2017, Journal of materials chemistry. B.

[27]  Kwang S. Kim,et al.  Engineered Carbon-Nanomaterial-Based Electrochemical Sensors for Biomolecules. , 2016, ACS nano.

[28]  Shuhong Yu,et al.  Ultrathin PtPdTe nanowires as superior catalysts for methanol electrooxidation. , 2013, Angewandte Chemie.

[29]  Qijin Wan,et al.  Lithium-doped NiO nanofibers for non-enzymatic glucose sensing , 2015 .

[30]  Dong Hoon Shin,et al.  Aptamer-functionalized hybrid carbon nanofiber FET-type electrode for a highly sensitive and selective platelet-derived growth factor biosensor. , 2014, ACS applied materials & interfaces.

[31]  K. Jandt,et al.  Protein-Promoted Synthesis of Pt Nanoparticles on Carbon Nanotubes for Electrocatalytic Nanohybrids with Enhanced Glucose Sensing , 2011 .

[32]  Xiao Kuang,et al.  Electrostatic Assembly of Peptide Nanofiber-Biomimetic Silver Nanowires onto Graphene for Electrochemical Sensors. , 2014, ACS macro letters.

[33]  Bhupender S. Gupta,et al.  Co‐axial Electrospinning for Nanofiber Structures: Preparation and Applications , 2008 .

[34]  Gang Wei,et al.  Chain conformation, crystallization behavior, electrical and mechanical properties of electrospun polymer-carbon nanotube hybrid nanofibers with different orientations , 2012 .

[35]  Shouzhuo Yao,et al.  Enhanced nonenzymatic sensing of hydrogen peroxide released from living cells based on Fe3O4/self-reduced graphene nanocomposites , 2014 .

[36]  Xingyu Jiang,et al.  Recent advances in electrospinning technology and biomedical applications of electrospun fibers. , 2014, Journal of materials chemistry. B.

[37]  Juan Wang,et al.  Facile fabrication of gold nanoparticles-poly(vinyl alcohol) electrospun water-stable nanofibrous mats: efficient substrate materials for biosensors. , 2012, ACS applied materials & interfaces.

[38]  Feng Yan,et al.  A sensitive hydrogen peroxide sensor based on a three-dimensional N-doped carbon nanotube-hemin modified electrode , 2015 .

[39]  Zhiqiang Su,et al.  Electrospinning graphene quantum dots into a nanofibrous membrane for dual-purpose fluorescent and electrochemical biosensors. , 2015, Journal of materials chemistry. B.

[40]  Addisu Getachew Destaye,et al.  Glutaraldehyde vapor cross-linked nanofibrous PVA mat with in situ formed silver nanoparticles. , 2013, ACS applied materials & interfaces.

[41]  Z. Qian,et al.  A fluorometric biosensor based on functional Au/Ag nanoclusters for real-time monitoring of tyrosinase activity. , 2016, Biosensors & bioelectronics.