The biology of cyclic nucleotide phosphodiesterases.

This volume of the "Advances in Second Messenger and Phosphoprotein Research" series focuses on the extensive progress that has been made in cyclic nucleotide phosphodiesterase research. Sections of the book cover biochemistry and molecular biology; regulatory and cellular biology; and basic pharmacology and clinical studies. Close attention is given to the development of new pharmacological agents that act on specific isozymes for the treatment of cardiovascular and pulmonary diseases, endocrine and metabolic disturbances, and neurologic and psychiatric disorders.