Visualization, Planning, and Monitoring Software for MRI-Guided Prostate Intervention Robot

This paper reports an interactive software interface for visualization, planning, and monitoring of intra-prostatic needle placement procedures performed with a robotic assistant device inside standard cylindrical high-field magnetic resonance imaging (MRI) scanner. We use anatomical visualization and image processing techniques to plan the process and apply active tracking coils to localize the robot in real-time to monitor its motion relative to the anatomy. The interventional system is in Phase-I clinical trials for prostate biopsy and marker seed placement. The system concept, mechanical design, and in-vivo canine studies have been presented earlier [6,10,14]. The software architecture and three-dimensional application software interface discussed in this paper are new additions. This software was tested on pre-recorded patient data.

[1]  Alicia Samuels,et al.  Cancer Statistics, 2003 , 2003, CA: a cancer journal for clinicians.

[2]  A. D'Amico,et al.  Transperineal magnetic resonance image guided prostate biopsy. , 2000, The Journal of urology.

[3]  Saroja Adusumilli,et al.  Magnetic resonance imaging of prostate cancer. , 2002, Seminars in urologic oncology.

[4]  Gabor Fichtinger,et al.  Transrectal Prostate Biopsy Inside Closed MRI Scanner with Remote Actuation, under Real-Time Image Guidance , 2002, MICCAI.

[5]  P Hofman,et al.  Feasibility of automatic marker detection with an a-Si flat-panel imager. , 2001, Physics in medicine and biology.

[6]  N. Hata,et al.  An integrated visualization system for surgical planning and guidance using image fusion and an open MR , 2001, Journal of magnetic resonance imaging : JMRI.

[7]  A. D'Amico,et al.  Real-time magnetic resonance image-guided interstitial brachytherapy in the treatment of select patients with clinically localized prostate cancer. , 1998, International journal of radiation oncology, biology, physics.

[8]  Gabor Fichtinger,et al.  Design of a novel MRI compatible manipulator for image guided prostate intervention , 2004, IEEE International Conference on Robotics and Automation, 2004. Proceedings. ICRA '04. 2004.

[9]  William J Catalona,et al.  Serial biopsy results in prostate cancer screening study. , 2002, The Journal of urology.

[10]  J C Presti,et al.  Prostate cancer: assessment of risk using digital rectal examination, tumor grade, prostate-specific antigen, and systematic biopsy. , 2000, Radiologic clinics of North America.

[11]  J. A. Derbyshire,et al.  System for MR image-guided prostate interventions: canine study. , 2003, Radiology.

[12]  J. A. Derbyshire,et al.  Dynamic scan‐plane tracking using MR position monitoring , 1998, Journal of Magnetic Resonance Imaging.

[13]  Ron Kikinis,et al.  Medical Image Computing and Computer-Assisted Intervention — MICCAI 2002 , 2002, Lecture Notes in Computer Science.