Amyloid-induced neurofibrillary tangle formation in Alzheimer's disease: insight from transgenic mouse and tissue-culture models
暂无分享,去创建一个
[1] Joseph E LeDoux. Emotion circuits in the brain. , 2009, Annual review of neuroscience.
[2] Feng Chen,et al. Posttranslational modifications of tau--role in human tauopathies and modeling in transgenic animals. , 2004, Current drug targets.
[3] J. Streffer,et al. Transgenic animal models of Alzheimer's disease and related disorders: histopathology, behavior and therapy , 2004, Molecular Psychiatry.
[4] E. Rogaev,et al. Role for glyoxalase I in Alzheimer's disease. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[5] R. Nitsch,et al. Accelerated extinction of conditioned taste aversion in P301L tau transgenic mice , 2004, Neurobiology of Disease.
[6] B. Penke,et al. Binding sites of amyloid beta-peptide in cell plasma membrane and implications for Alzheimer's disease. , 2004, Current protein & peptide science.
[7] R. Nitsch,et al. β-Amyloid Induces Paired Helical Filament-like Tau Filaments in Tissue Culture* , 2003, Journal of Biological Chemistry.
[8] J. Trojanowski,et al. Proteasome Inhibition Stabilizes Tau Inclusions in Oligodendroglial Cells that Occur after Treatment with Okadaic Acid , 2003, The Journal of Neuroscience.
[9] T. Arendt. Synaptic plasticity and cell cycle activation in neurons are alternative effector pathways: the ‘Dr. Jekyll and Mr. Hyde concept’ of Alzheimer’s disease or the yin and yang of neuroplasticity , 2003, Progress in Neurobiology.
[10] R. Berry,et al. Inhibition of tau polymerization by its carboxy-terminal caspase cleavage fragment. , 2003, Biochemistry.
[11] L. Murri,et al. Causative and susceptibility genes for Alzheimer’s disease: a review , 2003, Brain Research Bulletin.
[12] Kazuyuki Takata,et al. Cdk5 Is a Key Factor in Tau Aggregation and Tangle Formation In Vivo , 2003, Neuron.
[13] J. Morrison,et al. Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer’s disease , 2003, Neurology.
[14] J. Regula,et al. Reconstitution of γ-secretase activity , 2003, Nature Cell Biology.
[15] D. Geschwind,et al. Novel tau polymorphisms, tau haplotypes, and splicing in familial and sporadic frontotemporal dementia. , 2003, Archives of neurology.
[16] J. Morrison,et al. Stereologic analysis of neurofibrillary tangle formation in prefrontal cortex area 9 in aging and Alzheimer’s disease , 2003, Neuroscience.
[17] J. Poirier. Apolipoprotein E and cholesterol metabolism in the pathogenesis and treatment of Alzheimer's disease. , 2003, Trends in molecular medicine.
[18] Hirotaka Yoshida,et al. Abundant Tau Filaments and Nonapoptotic Neurodegeneration in Transgenic Mice Expressing Human P301S Tau Protein , 2002, The Journal of Neuroscience.
[19] T. Hashikawa,et al. Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[20] Jürgen Götz,et al. Glial cells under physiologic and pathologic conditions. , 2002, Archives of neurology.
[21] A. Delacourte,et al. Nonoverlapping but synergetic tau and APP pathologies in sporadic Alzheimer’s disease , 2002, Neurology.
[22] J. Trojanowski,et al. Transgenic Mouse Model of Tauopathies with Glial Pathology and Nervous System Degeneration , 2002, Neuron.
[23] P. Lansbury,et al. Neurodegenerative disease: Amyloid pores from pathogenic mutations , 2002, Nature.
[24] H. Braak,et al. Phases of Aβ-deposition in the human brain and its relevance for the development of AD , 2002, Neurology.
[25] M. Vitek,et al. Tau is essential to β-amyloid-induced neurotoxicity , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[26] T. Iwatsubo,et al. Late‐onset frontotemporal dementia with a novel exon 1 (Arg5His) tau gene mutation , 2002, Annals of neurology.
[27] S. Hoyer,et al. The brain insulin signal transduction system and sporadic (type II) Alzheimer disease: an update , 2002, Journal of Neural Transmission.
[28] G. Perry,et al. Formation of aberrant phosphotau fibrillar polymers in neural cultured cells. , 2002, European journal of biochemistry.
[29] T. Hashikawa,et al. Neurodegeneration with Tau Accumulation in a Transgenic Mouse Expressing V337M Human Tau , 2002, The Journal of Neuroscience.
[30] Akihiko Takashima,et al. Formation of Filamentous Tau Aggregations in Transgenic Mice Expressing V337M Human Tau , 2001, Neurobiology of Disease.
[31] H. Lipp,et al. Conditioned taste aversion as a learning and memory paradigm , 2001, Behavioural Brain Research.
[32] R. Nitsch,et al. Formation of Neurofibrillary Tangles in P301L Tau Transgenic Mice Induced by Aβ42 Fibrils , 2001, Science.
[33] J. Hardy,et al. Enhanced Neurofibrillary Degeneration in Transgenic Mice Expressing Mutant Tau and APP , 2001, Science.
[34] Jürgen Götz,et al. Tau and transgenic animal models , 2001, Brain Research Reviews.
[35] R. Nitsch,et al. Oligodendroglial tau filament formation in transgenic mice expressing G272V tau , 2001, The European journal of neuroscience.
[36] M. Zirlinger,et al. Amygdala-enriched genes identified by microarray technology are restricted to specific amygdaloid subnuclei , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[37] J. Trojanowski,et al. Age-dependent induction of congophilic neurofibrillary tau inclusions in tau transgenic mice. , 2001, The American journal of pathology.
[38] E. Tolosa,et al. Familial atypical progressive supranuclear palsy associated with homozigosity for the delN296 mutation in the tau gene , 2001, Annals of neurology.
[39] R. Nitsch,et al. Tau Filament Formation in Transgenic Mice Expressing P301L Tau* , 2001, The Journal of Biological Chemistry.
[40] M. Mercken,et al. Glycogen Synthase Kinase-3β Phosphorylates Protein Tau and Rescues the Axonopathy in the Central Nervous System of Human Four-repeat Tau Transgenic Mice* , 2000, The Journal of Biological Chemistry.
[41] R. Uitti,et al. Two brothers with frontotemporal dementia and parkinsonism with an N279K mutation of the tau gene , 2000, Neurology.
[42] G. Perry,et al. Phosphorylated, but not native, tau protein assembles following reaction with the lipid peroxidation product, 4‐hydroxy‐2‐nonenal , 2000, FEBS letters.
[43] J. Grafman,et al. Frontotemporal dementia with novel tau pathology and a Glu342Val tau mutation , 2000, Annals of neurology.
[44] T. Arendt,et al. Activated Mitogenic Signaling Induces a Process of Dedifferentiation in Alzheimer's Disease That Eventually Results in Cell Death , 2000, Annals of the New York Academy of Sciences.
[45] J. Trojanowski,et al. Distinct FTDP-17 missense mutations in tau produce tau aggregates and other pathological phenotypes in transfected CHO cells. , 2000, Molecular biology of the cell.
[46] J. Kuret,et al. C-terminal inhibition of tau assembly in vitro and in Alzheimer's disease. , 2000, Journal of cell science.
[47] Yuhui Liu,et al. Sequential Treatment of SH‐SY5Y Cells with Retinoic Acid and Brain‐Derived Neurotrophic Factor Gives Rise to Fully Differentiated, Neurotrophic Factor‐Dependent, Human Neuron‐Like Cells , 2000, Journal of neurochemistry.
[48] Xiongwei Zhu,et al. In Alzheimer's Disease, Heme Oxygenase Is Coincident with Alz50, an Epitope of τ Induced by 4‐Hydroxy‐2‐Nonenal Modification , 2000, Journal of neurochemistry.
[49] E. Mandelkow,et al. Structure, microtubule interactions, and paired helical filament aggregation by tau mutants of frontotemporal dementias. , 2000, Biochemistry.
[50] J. Lowe,et al. A new case of frontotemporal dementia and parkinsonism resulting from an intron 10 +3‐splice site mutation in the tau gene: clinical and pathological features , 2000, Neuropathology and applied neurobiology.
[51] Patrick R. Hof,et al. Tau protein isoforms, phosphorylation and role in neurodegenerative disorders 1 1 These authors contributed equally to this work. , 2000, Brain Research Reviews.
[52] M. Langdown,et al. Early-life programming of susceptibility to dysregulation of glucose metabolism and the development of Type 2 diabetes mellitus. , 2000, The Biochemical journal.
[53] Wen-Lang Lin,et al. Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein , 2000, Nature Genetics.
[54] Giancarlo V. De Ferrari and,et al. Wnt signaling function in Alzheimer’s disease , 2000, Brain Research Reviews.
[55] R. Brandt,et al. Interaction of Tau with the Neural Membrane Cortex Is Regulated by Phosphorylation at Sites That Are Modified in Paired Helical Filaments* , 2000, The Journal of Biological Chemistry.
[56] R. Uitti,et al. A mutation in the microtubule-associated protein tau in pallido-nigro- luysian degeneration [4] (multiple letters) , 2000 .
[57] K. Arima,et al. Two brothers with frontotemporal dementia and parkinsonism with an N279K mutation of the tau gene , 2000, Neurology.
[58] R. A. Crowther,et al. Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein , 2000, Acta Neuropathologica.
[59] G. Ugolini,et al. The neuronal microtubule associated protein tau is a substrate for caspase-3 and an effector of apoptosis , 2000, Neurobiology of Aging.
[60] S. Lovestone,et al. Does dysregulation of the Notch and wingless/Wnt pathways underlie the pathogenesis of Alzheimer's disease? , 2000, Molecular medicine today.
[61] H. Geerts,et al. Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein. , 1999, The American journal of pathology.
[62] S. Reske,et al. FTDP‐17: An early‐onset phenotype with parkinsonism and epileptic seizures caused by a novel mutation , 1999, Annals of neurology.
[63] Bin Zhang,et al. Age-Dependent Emergence and Progression of a Tauopathy in Transgenic Mice Overexpressing the Shortest Human Tau Isoform , 1999, Neuron.
[64] J. Treanor,et al. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. , 1999, Science.
[65] I. Lieberburg,et al. Cellular mechanisms of beta-amyloid production and secretion. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[66] G. Bloom,et al. Molecular Interactions among Protein Phosphatase 2A, Tau, and Microtubules , 1999, The Journal of Biological Chemistry.
[67] P. De Camilli,et al. A novel antineuronal antibody in a motor neuron syndrome associated with breast cancer , 1999, Neurology.
[68] Olivier Rascol,et al. A mutation at codon 279 (N279K) in exon 10 of the Tau gene causes a tauopathy with dementia and supranuclear palsy , 1999, Acta Neuropathologica.
[69] M G Spillantini,et al. Frontotemporal dementia and corticobasal degeneration in a family with a P301S mutation in tau. , 1999, Journal of neuropathology and experimental neurology.
[70] G. Schellenberg,et al. Missense and silent tau gene mutations cause frontotemporal dementia with parkinsonism-chromosome 17 type, by affecting multiple alternative RNA splicing regulatory elements. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[71] A. Delacourte,et al. The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer’s disease , 1999, Neurology.
[72] D. Dickson,et al. Tau gene mutation in familial progressive subcortical gliosis , 1999, Nature Medicine.
[73] R A Crowther,et al. Tau pathology in a family with dementia and a P301L mutation in tau. , 1999, Journal of neuropathology and experimental neurology.
[74] M. Hutton,et al. Accelerated filament formation from tau protein with specific FTDP‐17 missense mutations , 1999, FEBS letters.
[75] C. Duijn,et al. High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands. , 1999, American journal of human genetics.
[76] E. Mandelkow,et al. Overexpression of Tau Protein Inhibits Kinesin-dependent Trafficking of Vesicles, Mitochondria, and Endoplasmic Reticulum: Implications for Alzheimer's Disease , 1998, The Journal of cell biology.
[77] W. Kamphorst,et al. Tau pathology in two Dutch families with mutations in the microtubule-binding region of tau. , 1998, The American journal of pathology.
[78] E. Scherder,et al. Reduced neuronal activity and reactivation in Alzheimer's disease , 1998, European Neuropsychopharmacology.
[79] D. Geschwind,et al. Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[80] M. Goedert,et al. Tau proteins with FTDP‐17 mutations have a reduced ability to promote microtubule assembly , 1998, FEBS letters.
[81] Y. Agid,et al. Segregation of a missense mutation in the microtubule-associated protein tau gene with familial frontotemporal dementia and parkinsonism. , 1998, Human molecular genetics.
[82] Bruce A. Yankner,et al. Aging renders the brain vulnerable to amyloid β-protein neurotoxicity , 1998, Nature Medicine.
[83] A Klug,et al. Mutation in the tau gene in familial multiple system tauopathy with presenile dementia. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[84] Ronald C. Petersen,et al. Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17 , 1998, Nature.
[85] G. Schellenberg,et al. Tau is a candidate gene for chromosome 17 frontotemporal dementia , 1998, Annals of neurology.
[86] S. Jenkins,et al. Tau complexes with phospholipase C‐γ in situ , 1998 .
[87] P. Janmey,et al. The structure of divalent cation-induced aggregates of PIP2 and their alteration by gelsolin and tau. , 1997, Biophysical journal.
[88] T. Iwatsubo,et al. Somatodendritic localization of phosphorylated tau in neonatal and adult rat cerebral cortex , 1997, Neuroreport.
[89] V. Lee,et al. Insulin and Insulin-like Growth Factor-1 Regulate Tau Phosphorylation in Cultured Human Neurons* , 1997, The Journal of Biological Chemistry.
[90] Mark A. Smith,et al. 4‐Hydroxynonenal‐Derived Advanced Lipid Peroxidation End Products Are Increased in Alzheimer's Disease , 1997, Journal of neurochemistry.
[91] Richard Hollister,et al. Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease , 1997, Annals of neurology.
[92] P. Dijkhuizen,et al. Co-localization of high-affinity neurotrophin receptors in nucleus basalis of Meynert neurons and their differential reduction in Alzheimer's disease , 1996, Neuroscience.
[93] K. Kosik,et al. The pool of map kinase associated with microtubules is small but constitutively active. , 1996, Molecular biology of the cell.
[94] A. Smith,et al. Hippocampal pathology reflects memory deficit and brain imaging measurements in Alzheimer's disease: clinicopathologic correlations using three sets of pathologic diagnostic criteria. , 1996, Dementia.
[95] Guy A. Rouleau,et al. SOD1 mutation is assosiated with accumulation of neurofilaments in amyotrophic lateral scelaries , 1996 .
[96] E. Krebs,et al. Association of mitogen-activated protein kinase with the microtubule cytoskeleton. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[97] P. Cohen,et al. Molecular dissection of the paired helical filament , 1995, Neurobiology of Aging.
[98] D. Pollen,et al. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease , 1995, Nature.
[99] D. Swaab,et al. Decreased protein synthetic activity of the hypothalamic tuberomamillary nucleus in Alzheimer's disease as suggested by smaller Golgi apparatus , 1995, Neuroscience Letters.
[100] H. Braak,et al. Staging of alzheimer's disease-related neurofibrillary changes , 1995, Neurobiology of Aging.
[101] M. Goedert,et al. Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform. , 1995, The EMBO journal.
[102] E. Mandelkow,et al. Structural studies of tau protein and Alzheimer paired helical filaments show no evidence for beta-structure. , 1994, The Journal of biological chemistry.
[103] R. Ravid,et al. Decreased neuronal activity in the nucleus basalis of Meynert in Alzheimer's disease as suggested by the size of the Golgi apparatus , 1994, Neuroscience.
[104] G. Drewes,et al. Glycogen synthase kinase‐3 and the Alzheimer‐like state of microtubule‐associated protein tau , 1992, FEBS letters.
[105] C. Broeckhoven,et al. Mapping of a gene predisposing to early–onset Alzheimer's disease to chromosome 14q24.3 , 1992, Nature Genetics.
[106] B. Winblad,et al. A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N–terminus of β–amyloid , 1992, Nature Genetics.
[107] G. Lee,et al. Expression of tau protein in non-neuronal cells: microtubule binding and stabilization. , 1992, Journal of cell science.
[108] Bradley T. Hyman,et al. Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease , 1992, Neurology.
[109] N. Cairns,et al. Tau proteins of alzheimer paired helical filaments: Abnormal phosphorylation of all six brain isoforms , 1992, Neuron.
[110] HM Roder,et al. Two novel kinases phosphorylate tau and the KSP site of heavy neurofilament subunits in high stoichiometric ratios , 1991, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[111] M. Pericak-Vance,et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease , 1991, Nature.
[112] E. Mandelkow,et al. Structure and elasticity of microtubule-associated protein tau , 1988, Nature.
[113] J. Walker,et al. Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[114] D. Perl,et al. Accumulation of Phosphorylated Neurofilaments in Anterior Horn Motoneurons of Amyotrophic Lateral Sclerosis Patients , 1988, Journal of neuropathology and experimental neurology.
[115] R. Crowther,et al. Image reconstruction of the Alzheimer paired helical filament. , 1985, The EMBO journal.
[116] R. Crowther,et al. Subunit structure of paired helical filaments in Alzheimer's disease , 1985, The Journal of cell biology.
[117] C. Masters,et al. Amyloid plaque core protein in Alzheimer disease and Down syndrome. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[118] L. Kurland,et al. Fine Structural Study of Neurofibrillary Changes in a Family with Amyotrophic Lateral Sclerosis , 1984, Journal of neuropathology and experimental neurology.
[119] H. Braak,et al. Neuropathological stageing of Alzheimer-related changes , 2004, Acta Neuropathologica.
[120] J. Regula,et al. Reconstitution of gamma-secretase activity. , 2003, Nature cell biology.
[121] T. Montine,et al. Lipoproteins and lipid peroxidation in Alzheimer's disease. , 2003, The journal of nutrition, health & aging.
[122] R. Bowser,et al. Cell cycle proteins in Alzheimer's disease: plenty of wheels but no cycle. , 2002, Journal of Alzheimer's disease : JAD.
[123] M. Vitek,et al. Tau is essential to beta -amyloid-induced neurotoxicity. , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[124] J. Trojanowski,et al. Neurodegenerative tauopathies. , 2001, Annual review of neuroscience.
[125] M. Delisle,et al. Maladie neuro-dégénérative associée à une mutation du codon 279 (N279K) de l'exon 10 du gène de la protéine Tau. , 2000 .
[126] J. Brion,et al. Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer's disease. , 1999, The American journal of pathology.
[127] C. Geula,et al. Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity. , 1998, Nature medicine.
[128] G. Johnson,et al. Tau complexes with phospholipase C-gamma in situ. , 1998, Neuroreport.
[129] A. Clark,et al. SOD1 mutation is associated with accumulation of neurofilaments in amyotrophic lateral sclerosis. , 1996, Annals of neurology.
[130] L Carlin,et al. Neocortical neurofibrillary tangles correlate with dementia severity in Alzheimer's disease. , 1995, Archives of neurology.
[131] G. Glenner,et al. Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. , 1984, Biochemical and biophysical research communications.