Adenoviral mediated mono delivery of BMP2 is superior to the combined delivery of BMP2 and VEGFA in bone regeneration in a critical-sized rat calvarial bone defect

[1]  A. Finne‐Wistrand,et al.  Delivery of VEGFA in bone marrow stromal cells seeded in copolymer scaffold enhances angiogenesis, but is inadequate for osteogenesis as compared with the dual delivery of VEGFA and BMP2 in a subcutaneous mouse model , 2018, Stem Cell Research & Therapy.

[2]  B. Olsen,et al.  Soluble VEGFR1 reverses BMP2 inhibition of intramembranous ossification during healing of cortical bone defects , 2017, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[3]  Zhihong Wu,et al.  Synergistic Effects of Vascular Endothelial Growth Factor on Bone Morphogenetic Proteins Induced Bone Formation In Vivo: Influencing Factors and Future Research Directions , 2016, BioMed research international.

[4]  O. Bruland,et al.  Adenoviral Mediated Expression of BMP2 by Bone Marrow Stromal Cells Cultured in 3D Copolymer Scaffolds Enhances Bone Formation , 2016, PloS one.

[5]  H. Zadeh,et al.  Application of AMOR in Craniofacial Rabbit Bone Bioengineering , 2015, BioMed research international.

[6]  Zhaowei Lin,et al.  Effects of BMP2 and VEGF165 on the osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells , 2013, Experimental and therapeutic medicine.

[7]  I. Martin,et al.  Osteogenic graft vascularization and bone resorption by VEGF-expressing human mesenchymal progenitors. , 2013, Biomaterials.

[8]  H. Zadeh,et al.  Antibody-mediated osseous regeneration: the early events in the healing response. , 2013, Tissue engineering. Part A.

[9]  C. Evans,et al.  Gene delivery to bone. , 2012, Advanced drug delivery reviews.

[10]  David L Kaplan,et al.  The use of injectable sonication-induced silk hydrogel for VEGF(165) and BMP-2 delivery for elevation of the maxillary sinus floor. , 2011, Biomaterials.

[11]  Xiao-ying Zhang,et al.  BMP2 and VEGF promote angiogenesis but retard terminal differentiation of osteoblasts in bone regeneration by up-regulating Id1. , 2011, Acta biochimica et biophysica Sinica.

[12]  A. Albertsson,et al.  In vitro and in vivo degradation profile of aliphatic polyesters subjected to electron beam sterilization. , 2011, Acta biomaterialia.

[13]  A. Albertsson,et al.  Effect of endothelial cells on bone regeneration using poly(L-lactide-co-1,5-dioxepan-2-one) scaffolds. , 2011, Journal of biomedical materials research. Part A.

[14]  M. H. Fernandes,et al.  Rodent models in bone-related research: the relevance of calvarial defects in the assessment of bone regeneration strategies , 2011, Laboratory animals.

[15]  A. Albertsson,et al.  Growth and differentiation of bone marrow stromal cells on biodegradable polymer scaffolds: an in vitro study. , 2010, Journal of biomedical materials research. Part A.

[16]  A. Albertsson,et al.  Biocompatibility of Polyester Scaffolds with Fibroblasts and Osteoblast-like Cells for Bone Tissue Engineering , 2010 .

[17]  B. Mehrara,et al.  Vascular endothelial growth factor inhibits bone morphogenetic protein 2 expression in rat mesenchymal stem cells. , 2010, Tissue engineering. Part A.

[18]  A. Albertsson,et al.  Osteogenic Differentiation by Rat Bone Marrow Stromal Cells on Customized Biodegradable Polymer Scaffolds , 2010 .

[19]  Michael J Yaszemski,et al.  Effect of local sequential VEGF and BMP-2 delivery on ectopic and orthotopic bone regeneration. , 2009, Biomaterials.

[20]  Antonios G Mikos,et al.  Dose effect of dual delivery of vascular endothelial growth factor and bone morphogenetic protein-2 on bone regeneration in a rat critical-size defect model. , 2009, Tissue engineering. Part A.

[21]  B. Zheng,et al.  The dose of growth factors influences the synergistic effect of vascular endothelial growth factor on bone morphogenetic protein 4-induced ectopic bone formation. , 2009, Tissue engineering. Part A.

[22]  Johnny Huard,et al.  VEGF Improves, Whereas sFlt1 Inhibits, BMP2‐Induced Bone Formation and Bone Healing Through Modulation of Angiogenesis , 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[23]  A. Albertsson,et al.  Elastomeric hydrolyzable porous scaffolds: copolymers of aliphatic polyesters and a polyether-ester. , 2005, Biomacromolecules.

[24]  F. Kloss,et al.  Bone regeneration in critical size defects by cell-mediated BMP-2 gene transfer: a comparison of adenoviral vectors and liposomes , 2003, Gene Therapy.

[25]  Napoleone Ferrara,et al.  VEGF and the quest for tumour angiogenesis factors , 2002, Nature Reviews Cancer.

[26]  Johnny Huard,et al.  Synergistic enhancement of bone formation and healing by stem cell-expressed VEGF and bone morphogenetic protein-4. , 2002, The Journal of clinical investigation.

[27]  H. Redmond,et al.  Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[28]  E. Nevo,et al.  Adaptive hypoxic tolerance in the subterranean mole rat Spalax ehrenbergi: the role of vascular endothelial growth factor , 1999, FEBS letters.

[29]  C. Maniatopoulos,et al.  Bone formation in vitro by stromal cells obtained from bone marrow of young adult rats , 1988, Cell and Tissue Research.

[30]  J. Jacobs,et al.  Bone grafts and their substitutes. , 2016, The bone & joint journal.

[31]  王秀丽,et al.  The use of injectable sonication-induced silk hydrogel for VEGF165 and BMP-2 delivery for elevation of the maxillary sinus floor , 2011 .

[32]  M. Chapman,et al.  Morbidity at bone graft donor sites. , 1989, Journal of orthopaedic trauma.