The genetic basis of hyperuricaemia and gout.

[1]  叶夏,et al.  Gout , 2011 .

[2]  T. Merriman,et al.  A strong role for the ABCG2 gene in susceptibility to gout in New Zealand Pacific Island and Caucasian, but not Māori, case and control sample sets. , 2010, Human molecular genetics.

[3]  M. Caulfield,et al.  Replication of the five novel loci for uric acid concentrations and potential mediating mechanisms. , 2010, Human molecular genetics.

[4]  J. Erdmann,et al.  Common Polymorphisms Influencing Serum Uric Acid Levels Contribute to Susceptibility to Gout, but Not to Coronary Artery Disease , 2009, PloS one.

[5]  T. Merriman,et al.  Role of the urate transporter SLC2A9 gene in susceptibility to gout in New Zealand Māori, Pacific Island, and Caucasian case-control sample sets. , 2009, Arthritis and rheumatism.

[6]  Y. Ko,et al.  The SLC22A12 gene is associated with gout in Han Chinese and Solomon Islanders , 2009, Annals of the rheumatic diseases.

[7]  Y. Ko,et al.  Associations of a non-synonymous variant in SLC2A9 with gouty arthritis and uric acid levels in Han Chinese subjects and Solomon Islanders , 2009, Annals of the rheumatic diseases.

[8]  C. Antignac,et al.  Dominant renin gene mutations associated with early-onset hyperuricemia, anemia, and chronic kidney failure. , 2009, American journal of human genetics.

[9]  Rosario Dominguez Crespo Hirata,et al.  The expression of efflux and uptake transporters are regulated by statins in Caco-2 and HepG2 cells , 2009, Acta Pharmacologica Sinica.

[10]  H. Jinnah,et al.  Severe gouty arthritis and mild neurologic symptoms due to F199C, a newly identified variant of the hypoxanthine guanine phosphoribosyltransferase. , 2009, Arthritis and rheumatism.

[11]  A. Taniguchi,et al.  Sodium-dependent phosphate cotransporter type 1 sequence polymorphisms in male patients with gout , 2009, Annals of the rheumatic diseases.

[12]  E. Boerwinkle,et al.  Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout , 2009, Proceedings of the National Academy of Sciences.

[13]  Christian Gieger,et al.  Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations , 2009, PLoS genetics.

[14]  G. Núñez,et al.  The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis , 2009, Nature Immunology.

[15]  K. Dresser,et al.  A Role of IgM Antibodies in Monosodium Urate Crystal Formation and Associated Adjuvanticity1 , 2009, The Journal of Immunology.

[16]  M. Guan,et al.  High‐resolution melting analysis for the rapid detection of an intronic single nucleotide polymorphism in SLC22A12 in male patients with primary gout in China , 2009, Scandinavian journal of rheumatology.

[17]  A. Hofman,et al.  Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study , 2008, The Lancet.

[18]  M. Rieder,et al.  Common Missense Variant in the Glucokinase Regulatory Protein Gene Is Associated With Increased Plasma Triglyceride and C-Reactive Protein but Lower Fasting Glucose Concentrations , 2008, Diabetes.

[19]  T. Merriman,et al.  Crystal ball gazing: new therapeutic targets for hyperuricaemia and gout. , 2008, Rheumatology.

[20]  P. Elliott,et al.  SLC2A9 Is a High-Capacity Urate Transporter in Humans , 2008, PLoS medicine.

[21]  Hyon K. Choi,et al.  Gout and the risk of type 2 diabetes among men with a high cardiovascular risk profile. , 2008, Rheumatology.

[22]  Braxton D Mitchell,et al.  Association of a common nonsynonymous variant in GLUT9 with serum uric acid levels in old order amish. , 2008, Arthritis and rheumatism.

[23]  G. Gamble,et al.  Mechanisms of bone erosion in gout: a quantitative analysis using plain radiography and computed tomography , 2008, Annals of the rheumatic diseases.

[24]  B. Balkau,et al.  The Common P446L Polymorphism in GCKR Inversely Modulates Fasting Glucose and Triglyceride Levels and Reduces Type 2 Diabetes Risk in the DESIR Prospective General French Population , 2008, Diabetes.

[25]  S. Wiedmann,et al.  Association of Common Polymorphisms in GLUT9 Gene with Gout but Not with Coronary Artery Disease in a Large Case-Control Study , 2008, PloS one.

[26]  Hyon K. Choi,et al.  Soft drinks, fructose consumption, and the risk of gout in men: prospective cohort study , 2008, BMJ : British Medical Journal.

[27]  Mario Falchi,et al.  Genome-wide Association Study Identifies Genes for Biomarkers of Cardiovascular Disease: Serum Urate and Dyslipidemia , 2022 .

[28]  T. Nielsen,et al.  The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes , 2007, Diabetologia.

[29]  H. Buckley Possible Gouty Arthritis in Lapita‐Associated Skeletons from Teouma, Efate Island, Central Vanuatu , 2007, Current Anthropology.

[30]  S. Bandinelli,et al.  The GLUT9 Gene Is Associated with Serum Uric Acid Levels in Sardinia and Chianti Cohorts , 2007, PLoS genetics.

[31]  Y. Kanai,et al.  New insights into renal transport of urate , 2007, Current opinion in rheumatology.

[32]  T. Merriman,et al.  The human genome and understanding of common disease: present and future technologies , 2007, Cellular and Molecular Life Sciences.

[33]  Hassan Fouayzi,et al.  Validity of gout diagnoses in administrative data. , 2007, Arthritis and rheumatism.

[34]  Chaoyang Li,et al.  Prevalence of the metabolic syndrome in patients with gout: the Third National Health and Nutrition Examination Survey. , 2007, Arthritis and rheumatism.

[35]  G. Burckhardt,et al.  Human renal organic anion transporter 4 operates as an asymmetric urate transporter. , 2007, Journal of the American Society of Nephrology : JASN.

[36]  P. Underhill,et al.  Melanesian and Asian origins of Polynesians: mtDNA and Y chromosome gradients across the Pacific. , 2006, Molecular biology and evolution.

[37]  R. Burgos-Vargas,et al.  Molecular analysis of the SLC22A12 (URAT1) gene in patients with primary gout. , 2006, Rheumatology.

[38]  F. Martinon,et al.  Gout-associated uric acid crystals activate the NALP3 inflammasome , 2006, Nature.

[39]  N. Dalbeth,et al.  Mechanisms of inflammation in gout. , 2005, Rheumatology.

[40]  Hyon K. Choi,et al.  Obesity, weight change, hypertension, diuretic use, and risk of gout in men: the health professionals follow-up study. , 2005, Archives of internal medicine.

[41]  W. Hörl,et al.  Tamm‐Horsfall protein: a multilayered defence molecule against urinary tract infection , 2005, European journal of clinical investigation.

[42]  J. Moley,et al.  Identification and Characterization of Human Glucose Transporter-like Protein-9 (GLUT9) , 2004, Journal of Biological Chemistry.

[43]  M. Gorry,et al.  Clinical characterization of a family with a mutation in the uromodulin (Tamm-Horsfall glycoprotein) gene. , 2003, Kidney international.

[44]  Hirotaka Matsuo,et al.  Molecular identification of a renal urate–anion exchanger that regulates blood urate levels , 2002, Nature.

[45]  P. Rellos,et al.  Hereditary fructose intolerance. , 1998, Journal of medical genetics.

[46]  M. Robertson,et al.  Gout is on the increase in New Zealand , 1997, Annals of the rheumatic diseases.

[47]  H. Simmonds,et al.  Polynesian women are also at risk for hyperuricaemia and gout because of a genetic defect in renal urate handling. , 1994, British journal of rheumatology.

[48]  B. Roessler,et al.  Human X-linked phosphoribosylpyrophosphate synthetase superactivity is associated with distinct point mutations in the PRPS1 gene. , 1993, The Journal of biological chemistry.

[49]  G. Reaven,et al.  Relationship between resistance to insulin-mediated glucose uptake, urinary uric acid clearance, and plasma uric acid concentration. , 1991, JAMA.

[50]  Truls Østbye,et al.  Migration and gout: the Tokelau Island migrant study. , 1987, British medical journal.

[51]  H. Schumacher,et al.  Monosodium urate crystals in the knee joints of patients with asymptomatic nontophaceous gout. , 1986, Arthritis and rheumatism.

[52]  K. Bremner,et al.  Hyperuricaemia, gout and kidney function in New Zealand Maori men. , 1984, British journal of rheumatology.

[53]  I. Pool Is New Zealand a healthy country , 1982 .

[54]  L. Prior Epidemiology of Rheumatic disorders in the Pacific with particular emphasis on hyperuricaemia and gout. , 1981, Seminars in arthritis and rheumatism.

[55]  D. Mccarty,et al.  Preliminary criteria for the classification of the acute arthritis of primary gout. , 1977, Arthritis and rheumatism.

[56]  W. N. Kelley,et al.  Studies on the mechanism of fructose-induced hyperuricemia in man. , 1972, Metabolism: clinical and experimental.

[57]  William A. Richardson,et al.  SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout , 2008, Nature Genetics.

[58]  C. Gieger,et al.  SLC2A9 influences uric acid concentrations with pronounced sex-specific effects , 2008, Nature Genetics.

[59]  Hyon K. Choi,et al.  Sugar-sweetened soft drinks, diet soft drinks, and serum uric acid level: the Third National Health and Nutrition Examination Survey. , 2008, Arthritis and rheumatism.

[60]  D. Muzny,et al.  Two independent mutational events in the loss of urate oxidase during hominoid evolution , 2004, Journal of Molecular Evolution.