Sterilization Methods and the Comparison of E-Beam Sterilization with Gamma Radiation Sterilization

Sterilization is used in a varity of industry field and a strictly required process for some products used in sterile regions of the body like some medical devices and parenteral drugs. Although there are many kinds of sterilization methods according to physicochemical properties of the substances, the use of radiation in sterilization has many advantages depending on its substantially less toxicity. The use of radiation in industrial field showed 10-15% increase per every year of the previous years and by 1994 more than 180 gamma irradiation institutions have functioned in 50 countries. As principle radiosterilization utilizes ionizing radiation and is a terminal sterilization method.

[1]  W. Roos,et al.  The effect of ethylene oxide, glow discharge and electron beam on the surface characteristics of poly(L-lactide-co-caprolactone) and the corresponding cellular response of adipose stem cells. , 2010, Acta biomaterialia.

[2]  Y. Ozaki,et al.  Direct determination of peracetic acid, hydrogen peroxide, and acetic acid in disinfectant solutions by far-ultraviolet absorption spectroscopy. , 2005, Analytical Chemistry.

[3]  M. E. Fray,et al.  Physical and mechanical behavior of electron-beam irradiated and ethylene oxide sterilized multiblock polyester , 2000, Journal of materials science. Materials in medicine.

[4]  J. Barker.  Ethylene oxide sterilization update. , 1995, Medical device technology.

[5]  B. D. Reid.  Gamma processing technology: an alternative technology for terminal sterilization of parenterals. , 1995, PDA journal of pharmaceutical science and technology.

[6]  E. Kempner.  Effects of high-energy electrons and gamma rays directly on protein molecules. , 2001, Journal of pharmaceutical sciences.

[7]  Cristina L. M. Silva,et al.  Ethylene oxide sterilization of medical devices: a review. , 2007, American journal of infection control.

[8]  N. Hilmy,et al.  Guide for radiation sterilization of pharmaceuticals and decontamination of raw materials , 1988 .

[9]  W. Hijnen,et al.  Inactivation credit of UV radiation for viruses, bacteria and protozoan (oo)cysts in water: a review. , 2006, Water research.

[10]  Mehmet Kitis,et al.  Disinfection of wastewater with peracetic acid: a review. , 2004, Environment international.

[11]  S. Crow.  Peracetic acid sterilization: a timely development for a busy healthcare industry. , 1992, Infection control and hospital epidemiology.

[12]  SUSUMU URANO,et al.  Electron Beam Sterilization System , 2003 .

[13]  Collins Ch,et al.  Formaldehyde disinfection in laboratories: limitations and hazards. , 1995 .

[14]  J. Kreuter,et al.  Radiation sterilisation of doxorubicin bound to poly(butyl cyanoacrylate) nanoparticles. , 2008, International journal of pharmaceutics.

[15]  M. Furuta,et al.  Electron-beam sterilization of laboratory animal diets--sterilizing effect of 10-MeV electrons from a linear accelerator. , 2002, Experimental animals.

[16]  Michael Donley,et al.  UV irradiation and autoclave treatment for elimination of contaminating DNA from laboratory consumables. , 2010, Forensic science international. Genetics.