SH2 and SH3 domains

[1]  D. Bar-Sagi,et al.  SH3 domains direct cellular localization of signaling molecules , 1993, Cell.

[2]  I. Campbell,et al.  Solution structure and ligand-binding site of the SH3 domain of the p85α subunit of phosphatidylinositol 3-kinase , 1993, Cell.

[3]  Nanxin Li,et al.  Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling , 1993, Nature.

[4]  R. Weinberg,et al.  Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation , 1993, Nature.

[5]  A. Ullrich,et al.  The SH2/SH3 domain‐containing protein GRB2 interacts with tyrosine‐phosphorylated IRS1 and Shc: implications for insulin control of ras signalling. , 1993, The EMBO journal.

[6]  T. Pawson,et al.  Regulation of c-Src tyrosine kinase activity by the Src SH2 domain. , 1993, Oncogene.

[7]  G. Rubin,et al.  An SH3-SH2-SH3 protein is required for p21 Ras1 activation and binds to sevenless and Sos proteins in vitro , 1993, Cell.

[8]  E. Hafen,et al.  A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos , 1993, Cell.

[9]  J. Kuriyan,et al.  Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: Crystal structures of the complexed and peptide-free forms , 1993, Cell.

[10]  T. Pawson,et al.  SH2 domains recognize specific phosphopeptide sequences , 1993, Cell.

[11]  SH2 domains exhibit high-affinity binding to tyrosine-phosphorylated peptides yet also exhibit rapid dissociation and exchange. , 1993, Molecular and cellular biology.

[12]  S. Schreiber,et al.  Solution structure of the SH3 domain of Src and identification of its ligand-binding site. , 1992, Science.

[13]  U. Hellman,et al.  Identification of two C‐terminal autophosphorylation sites in the PDGF beta‐receptor: involvement in the interaction with phospholipase C‐gamma. , 1992, The EMBO journal.

[14]  T. Pawson,et al.  SH2 and SH3 domains: From structure to function , 1992, Cell.

[15]  D. Bowtell,et al.  Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[16]  T. Pawson,et al.  A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction , 1992, Cell.

[17]  T. Pawson,et al.  Tyr721 regulates specific binding of the CSF‐1 receptor kinase insert to PI 3′‐kinase SH2 domains: a model for SH2‐mediated receptor‐target interactions. , 1992, The EMBO journal.

[18]  A. Reith,et al.  SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors , 1992, Molecular and cellular biology.

[19]  M. Moran,et al.  Multiple SH2-mediated interactions in v-src-transformed cells , 1992, Molecular and cellular biology.

[20]  A. Ullrich,et al.  SH2 domains prevent tyrosine dephosphorylation of the EGF receptor: identification of Tyr992 as the high‐affinity binding site for SH2 domains of phospholipase C gamma. , 1992, The EMBO journal.

[21]  J. Cleveland,et al.  Protein tyrosine phosphatase containing SH2 domains: characterization, preferential expression in hematopoietic cells, and localization to human chromosome 12p12-p13 , 1992, Molecular and cellular biology.

[22]  B. Neel,et al.  Isolation of a src homology 2-containing tyrosine phosphatase. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[23]  D. Baltimore,et al.  Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo , 1992, Molecular and cellular biology.

[24]  U. Banerjee,et al.  The Son of sevenless gene product: a putative activator of Ras. , 1992, Science.

[25]  A. Brown,et al.  GAP domains responsible for ras p21-dependent inhibition of muscarinic atrial K+ channel currents. , 1992, Science.

[26]  D. Shalloway,et al.  Selective binding of activated pp60c-src by an immobilized synthetic phosphopeptide modeled on the carboxyl terminus of pp60c-src. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[27]  M. Jaye,et al.  A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1 , 1991, Molecular and cellular biology.

[28]  P. Chrétien,et al.  A protein-tyrosine phosphatase with sequence similarity to the SH2 domain of the protein-tyrosine kinases , 1991, Nature.

[29]  L. Marky,et al.  Differential hydration of dA.dT base pairing and dA and dT bulges in deoxyoligonucleotides. , 1991, Biochemistry.

[30]  O. Witte,et al.  BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner , 1991, Cell.

[31]  C. Kahn,et al.  Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein , 1991, Nature.

[32]  J. Parsons,et al.  The SH2 and SH3 domains of pp60src direct stable association with tyrosine phosphorylated proteins p130 and p110. , 1991, The EMBO journal.

[33]  S. Lo,et al.  Presence of an SH2 domain in the actin-binding protein tensin. , 1991, Science.

[34]  T Pawson,et al.  SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins. , 1991, Science.

[35]  A. Zilberstein,et al.  PDGF stimulation of inositol phospholipid hydrolysis requires PLC-γ1 phosphorylation on tyrosine residues 783 and 1254 , 1991, Cell.

[36]  G. Panayotou,et al.  Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase , 1991, Cell.

[37]  V. Fried,et al.  cDNA cloning of a Novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor , 1991, Cell.

[38]  A. Ullrich,et al.  Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases , 1991, Cell.

[39]  H. Hanafusa,et al.  Requirement of phosphatidylinositol-3 kinase modification for its association with p60src , 1991, Molecular and cellular biology.

[40]  M. Moran,et al.  Protein-tyrosine kinases regulate the phosphorylation, protein interactions, subcellular distribution, and activity of p21ras GTPase-activating protein , 1991, Molecular and cellular biology.

[41]  H. Hanafusa,et al.  Deletions in the SH2 domain of p60v-src prevent association with the detergent-insoluble cellular matrix , 1991, Molecular and cellular biology.

[42]  J. Griffith,et al.  Effects of bulge composition and flanking sequence on the kinking of DNA by bulged bases. , 1991, Biochemistry.

[43]  C. Turck,et al.  A phosphatidylinositol-3 kinase binds to platelet-derived growth factor receptors through a specific receptor sequence containing phosphotyrosine , 1991, Molecular and cellular biology.

[44]  L. Cantley,et al.  Oncogenes and signal transduction , 1991, Cell.

[45]  M. Moran,et al.  Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors. , 1990, Science.

[46]  L. Cantley,et al.  Purification and characterization of phosphoinositide 3-kinase from rat liver. , 1990, The Journal of biological chemistry.

[47]  T Pawson,et al.  Src homology region 2 domains direct protein-protein interactions in signal transduction. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[48]  B. Mayer,et al.  Binding of transforming protein, P47gag-crk, to a broad range of phosphotyrosine-containing proteins. , 1990, Science.

[49]  H. Hanafusa,et al.  Activation of the proto-oncogene p60c-src by point mutations in the SH2 domain , 1990, Molecular and cellular biology.

[50]  Joseph Schlessinger,et al.  Signal transduction by receptors with tyrosine kinase activity , 1990, Cell.

[51]  H. Varmus,et al.  Site-directed mutagenesis of the SH2- and SH3-coding domains of c-src produces varied phenotypes, including oncogenic activation of p60c-src , 1990, Molecular and cellular biology.

[52]  David Botstein,et al.  Homology of a yeast actin-binding protein to signal transduction proteins and myosin-I , 1990, Nature.

[53]  T. Pawson,et al.  Receptor tyrosine kinases: genetic evidence for their role in Drosophila and mouse development. , 1990, Trends in genetics : TIG.

[54]  D. Baltimore,et al.  N‐terminal mutations activate the leukemogenic potential of the myristoylated form of c‐abl. , 1989, The EMBO journal.

[55]  G. Martin,et al.  Linker insertion-deletion mutagenesis of the v-src gene: isolation of host- and temperature-dependent mutants , 1989, Journal of virology.

[56]  J. Parsons,et al.  Deletions and insertions within an amino-terminal domain of pp60v-src inactivate transformation and modulate membrane stability , 1989, Journal of virology.