Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer

[1]  H. Moch,et al.  A clearer view of the molecular complexity of clear cell renal cell carcinoma. , 2015, Annual review of pathology.

[2]  Y. Yung,et al.  LPA receptor signaling: pharmacology, physiology, and pathophysiology , 2014, Journal of Lipid Research.

[3]  S. Fukuda,et al.  High level expression of AMAP1 protein correlates with poor prognosis and survival after surgery of head and neck squamous cell carcinoma patients , 2014, Cell Communication and Signaling.

[4]  P. A. Futreal,et al.  Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing , 2014, Nature Genetics.

[5]  H. Shirato,et al.  Co-Overexpression of GEP100 and AMAP1 Proteins Correlates with Rapid Local Recurrence after Breast Conservative Therapy , 2013, PloS one.

[6]  Sridhar Ramaswamy,et al.  Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition , 2013, Science.

[7]  G. Berx,et al.  Regulatory networks defining EMT during cancer initiation and progression , 2013, Nature Reviews Cancer.

[8]  H. Shirato,et al.  Rab5c promotes AMAP1–PRKD2 complex formation to enhance β1 integrin recycling in EGF-induced cancer invasion , 2012, The Journal of cell biology.

[9]  P. A. Futreal,et al.  Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. , 2012, The New England journal of medicine.

[10]  H. Wada,et al.  Engagement of Overexpressed Her2 with GEP100 Induces Autonomous Invasive Activities and Provides a Biomarker for Metastases of Lung Adenocarcinoma , 2011, PloS one.

[11]  C. L. Jackson,et al.  ARF family G proteins and their regulators: roles in membrane transport, development and disease , 2011, Nature Reviews Molecular Cell Biology.

[12]  Ann Pellegrini Movement , 2011 .

[13]  M. Aittaleb,et al.  Structure and Function of Heterotrimeric G Protein-Regulated Rho Guanine Nucleotide Exchange Factors , 2010, Molecular Pharmacology.

[14]  B. Teh,et al.  Sunitinib acts primarily on tumor endothelium rather than tumor cells to inhibit the growth of renal cell carcinoma. , 2010, Cancer research.

[15]  D. Mukhopadhyay,et al.  Neuropilin-1 upholds dedifferentiation and propagation phenotypes of renal cell carcinoma cells by activating Akt and sonic hedgehog axes. , 2008, Cancer research.

[16]  E. Sahai,et al.  Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement , 2008, Cell.

[17]  Y. Okada,et al.  Expression of Heparanase in Renal Cell Carcinomas: Implications for Tumor Invasion and Prognosis , 2008, Clinical Cancer Research.

[18]  S. Aizawa,et al.  EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial–mesenchymal transition , 2008, The Journal of cell biology.

[19]  Wenjun Guo,et al.  The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells , 2008, Cell.

[20]  J. Casanova Regulation of Arf Activation: the Sec7 Family of Guanine Nucleotide Exchange Factors , 2007, Traffic.

[21]  M. Hafner,et al.  Inhibition of cytohesins by SecinH3 leads to hepatic insulin resistance , 2006, Nature.

[22]  H. Hosaka,et al.  Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[23]  R Y Ball,et al.  Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs , 2005 .

[24]  J. Lam,et al.  Novel approaches in the therapy of metastatic renal cell carcinoma , 2005, World Journal of Urology.

[25]  T. Manabe,et al.  Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities , 2005, The EMBO journal.

[26]  Y. Onodera,et al.  Requirement for Arf6 in breast cancer invasive activities. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[27]  F. Erdoğan,et al.  Prognostic significance of morphologic parameters in renal cell carcinoma , 2004, International journal of clinical practice.

[28]  H. Hanafusa,et al.  Refractory nature of normal human diploid fibroblasts with respect to oncogene-mediated transformation , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[29]  G. Mills,et al.  The emerging role of lysophosphatidic acid in cancer , 2003, Nature Reviews Cancer.

[30]  P. Friedl,et al.  Tumour-cell invasion and migration: diversity and escape mechanisms , 2003, Nature Reviews Cancer.

[31]  Peter Friedl,et al.  Compensation mechanism in tumor cell migration , 2003, The Journal of cell biology.

[32]  B. Giepmans,et al.  Rac Activation by Lysophosphatidic Acid LPA1Receptors through the Guanine Nucleotide Exchange Factor Tiam1* , 2003, The Journal of Biological Chemistry.

[33]  S. Petersen,et al.  Identification of human renal cell carcinoma associated genes by suppression subtractive hybridization , 2001, British Journal of Cancer.

[34]  C. L. Jackson,et al.  Turning on ARF: the Sec7 family of guanine-nucleotide-exchange factors. , 2000, Trends in cell biology.

[35]  S. Frisch,et al.  Disruption of epithelial cell-matrix interactions induces apoptosis , 1994, The Journal of cell biology.

[36]  Anne J. Ridley,et al.  The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors , 1992, Cell.

[37]  L. Liotta,et al.  Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein. , 1992, The Journal of biological chemistry.

[38]  R. Cailleau,et al.  Tissue culture studies on pleural effusions from breast carcinoma patients. , 1974, Cancer research.

[39]  T. Manabe,et al.  GEP100 links epidermal growth factor receptor signalling to Arf6 activation to induce breast cancer invasion , 2008, Nature Cell Biology.

[40]  A. Strongin,et al.  Compensation mechanism in tumor cell migration: mesenchymal–amoeboid transition after blocking of pericellular proteolysis , 2003 .

[41]  M. Karno,et al.  Renal cell carcinoma. , 1956, Bulletin. Tufts-New England Medical Center.