Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits
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Gabriëlle H S Buitendijk | Alan M. Kwong | R. T. Smith | Terrie E. Kitchner | Chelsea E. Myers | G. Abecasis | J. Haines | M. Pericak-Vance | Mingyao Li | D. Weeks | I. Chowers | T. Léveillard | J. Sahel | P. Campochiaro | D. Zack | C. Curcio | I. Constable | Cindy Wen | W. Scott | K. Stark | K. Doheny | L. Farrer | E. Chew | M. Hauser | A. Agarwal | E. Postel | I. Heid | M. Brilliant | A. D. den Hollander | Xiaowei Zhan | C. V. van Duijn | A. Swaroop | Jie-Jin Wang | C. Kiel | J. Blangero | Kristine E. Lee | B. Klein | D. Mackey | F. Grassmann | T. Langmann | H. Blanché | T. Kitchner | N. Katsanis | C. Hayward | E. Souied | S. Meuer | R. Guymer | L. Fritsche | M. Othman | S. Hebbring | S. Sengupta | J. Bragg-Gresham | C. Brandl | M. Klein | R. Ratnapriya | J. Heckenlively | G. Liew | R. Laux | Matthew P Johnson | Jane M. Romm | W. Igl | M. Gorin | M. Gorski | A. Hewitt | C. Hoyng | D. Schaumberg | S. Fauser | M. Brantley | J. Deleuze | J. C. Bailey | E. Souzeau | J. Craig | K. Burdon | V. Cipriani | A. Moore | R. Allikmets | Zhenglin Yang | J. Yates | M. Morrison | M. DeAngelis | A. Brucker | I. McAllister | S. Iyengar | Ken Flagg | Danni Lin | Z. Su | G. Silvestri | K. Branham | A. Lotery | Veronika Grassmann | P. Baird | E. D. de Jong | A. Cree | N. Peachey | A. Orlin | M. Brooks | S. Hagstrom | K. Park | C. Klaver | Kang Zhang | J. Merriam | A. Richardson | J. Khan | H. Shahid | M. Schu | R. Igo | I. Audo | M. Benchaboune | M. Cain | H. Ferreyra | Frank G. Holz | Ivana K. Kim | Jaclyn L Kovach | S. Mohand-Saïd | Denise J. Morgan | G. Rudolph | S. G. Schwartz | E. Tsironi | Monique D. Courtenay | L. Gieser | B. Gopinath | B. Vote | T. Isaacs | J. Merriam | F. Blond | A. Tan | S. Goverdhan | Jeeyun Ahn | Johanna R. Foerster | David Cho | E. Bala | Joshua D Hoffman | T. Schick | Yingda Jiang | Chloe M. Stanton | Alexis Boleda | H. Liang | Janette Hall | Hongrong Luo | Daniel Chen | H. Ouyang | Guanping Mao | C. V. von Strachwitz | A. Wolf | C. Rennie | Michelle Grunin | Shira Hagbi-Levi | E. Moore | J. McGrath | L. Ersoy | A. Caramoy | Nicole T. M. Saksens | T. Martin | Baldev Dhillon | D. Stambolian | R. Sardell | R. Klein | D. J. Hunter | P. Mitchell | Y. Lechanteur | B. H. Weber | Barbara J. Truitt | M. Olden | M. Zimmermann | Stewart R. Lake | Lars G. Wilmar Jessica N. Cooke Felix Sebanti Jennifer Fritsche Igl Bailey Grassmann Sengupta Bragg | Joanna E. Merriam | John C. Merriam | Hendrik P. N. Scholl | K. Zhang | K. Zhang | Kang Zhang | B. Weber | M. Grunin | B. Dhillon | A. Moore | Mathias Gorski | F. Holz | Sebanti Sengupta | Helena H. Liang | Barbara Truitt | Ouyang Hong | Alan Kwong | C. V. van Duijn | W. Scott | Paul Mitchell | Felix Grassmann | Mathias Gorski | Klaus Stark | H. Scholl | shira Hagbi-levi | Iris M. Heid | Emily L. Moore | Bernhard H.F. Weber | Klaus J. Stark | Paul A. Mitchell | Klaus Stark | J. Haines | Klaus Stark | Iris M. Heid | Emmanuelle Souzeau | Lebriz Ersoy | I. M. Heid | Klaus Stark | Klaus Stark | I. Heid | Klaus Stark | Klaus Stark
[1] Gabriëlle H S Buitendijk,et al. Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits , 2017, Genome Medicine.
[2] P. Mitchell,et al. Assessment of polygenic effects links primary open-angle glaucoma and age-related macular degeneration , 2016, Scientific Reports.
[3] F. Grassmann,et al. Multiallelic copy number variation in the complement component 4A (C4A) gene is associated with late-stage age-related macular degeneration (AMD) , 2016, Journal of Neuroinflammation.
[4] C. Spencer,et al. A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects: CNV Analysis Group and the Schizophrenia Working Group of the Psychiatric Genomics Consortium , 2016, bioRxiv.
[5] Yara T. E. Lechanteur,et al. Nature Genetics Advance Online Publication , 2022 .
[6] Robert N Weinreb,et al. Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open angle glaucoma , 2015, Nature Genetics.
[7] Daniel L. Chao,et al. Refractive Error and the Risk of Age-Related Macular Degeneration in the South Korean Population , 2016, Asia-Pacific journal of ophthalmology.
[8] M. Goldacre,et al. ASSOCIATIONS BETWEEN AGE-RELATED MACULAR DEGENERATION, OSTEOARTHRITIS AND RHEUMATOID ARTHRITIS: Record Linkage Study , 2015, Retina.
[9] A. D. den Hollander,et al. Genetic Variants and Systemic Complement Activation Levels Are Associated With Serum Lipoprotein Levels in Age-Related Macular Degeneration. , 2015, Investigative ophthalmology & visual science.
[10] Thomas Ach,et al. What Does Genetics Tell Us About Age-Related Macular Degeneration? , 2015, Annual review of vision science.
[11] David M. Evans,et al. Multi-ethnic genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis , 2015, Nature Genetics.
[12] J. Rioux,et al. Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus , 2015, Nature Genetics.
[13] Jennifer G. Robinson,et al. Association between vitamin D status and age-related macular degeneration by genetic risk. , 2015, JAMA ophthalmology.
[14] Marko Hočevar,et al. Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma , 2015, Nature Genetics.
[15] Herng‐Ching Lin,et al. Association between psoriasis and neovascular age-related macular degeneration: A population-based study. , 2015, Journal of the American Academy of Dermatology.
[16] Aung Ko Win,et al. A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer , 2015, Scientific Reports.
[17] E. Chew,et al. Clinical and Genetic Factors Associated with Progression of Geographic Atrophy Lesions in Age-Related Macular Degeneration , 2015, PloS one.
[18] Mario Roederer,et al. The Genetic Architecture of the Human Immune System: A Bioresource for Autoimmunity and Disease Pathogenesis , 2015, Cell.
[19] M. Daly,et al. An Atlas of Genetic Correlations across Human Diseases and Traits , 2015, Nature Genetics.
[20] Patrick Neven,et al. Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer , 2015 .
[21] Adriana I. Iglesias,et al. Meta‐analysis of Genome‐Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology , 2015, Genetic epidemiology.
[22] Ross M. Fraser,et al. Genetic studies of body mass index yield new insights for obesity biology , 2015, Nature.
[23] Tamara S. Roman,et al. New genetic loci link adipose and insulin biology to body fat distribution , 2014, Nature.
[24] Weidinger,et al. Genetics (AAGC) (2015). Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis. , 2015 .
[25] T. Lumley,et al. gplots: Various R Programming Tools for Plotting Data , 2015 .
[26] Blue Mountains Eye Study-GWAS groupw,et al. Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process , 2014 .
[27] Adriana I. Iglesias,et al. Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process , 2014, Nature Communications.
[28] Peter Kraft,et al. A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer , 2014, Nature Genetics.
[29] G. Abecasis,et al. Age-related macular degeneration: genetics and biology coming together. , 2014, Annual review of genomics and human genetics.
[30] Gabriëlle H S Buitendijk,et al. Lipids, lipid genes, and incident age-related macular degeneration: the three continent age-related macular degeneration consortium. , 2014, American journal of ophthalmology.
[31] C. Spencer,et al. Biological Insights From 108 Schizophrenia-Associated Genetic Loci , 2014, Nature.
[32] Correction: Age-Related Macular Degeneration and the Incidence of Cardiovascular Disease: A Systematic Review and Meta-Analysis , 2014, PLoS ONE.
[33] Chuong B. Do,et al. Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson’s disease , 2014, Nature Genetics.
[34] Lorna M. Lopez,et al. Genome-wide association analysis identifies six new loci associated with forced vital capacity , 2014, Nature Genetics.
[35] S. Camelo. Potential Sources and Roles of Adaptive Immunity in Age-Related Macular Degeneration: Shall We Rename AMD into Autoimmune Macular Disease? , 2014, Autoimmune diseases.
[36] Ronald Klein,et al. Markers of inflammation, oxidative stress, and endothelial dysfunction and the 20-year cumulative incidence of early age-related macular degeneration: the Beaver Dam Eye Study. , 2014, JAMA ophthalmology.
[37] D. Schaumberg,et al. Age-Related Macular Degeneration and the Incidence of Cardiovascular Disease: A Systematic Review and Meta-Analysis , 2014, PloS one.
[38] P. Barberger‐Gateau,et al. Elevated High-Density Lipoprotein Cholesterol and Age-Related Macular Degeneration: The Alienor Study , 2014, PloS one.
[39] Y. Li,et al. Refractive Error and Risk of Early or Late Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis , 2014, PloS one.
[40] Tanya M. Teslovich,et al. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility , 2014, Nature Genetics.
[41] R. Klein,et al. Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis. , 2014, The Lancet. Global health.
[42] Jun S. Liu,et al. Genetics of rheumatoid arthritis contributes to biology and drug discovery , 2013 .
[43] Daniel R. Zerbino,et al. Ensembl 2014 , 2013, Nucleic Acids Res..
[44] Aneela Majid,et al. A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia , 2013, Nature Genetics.
[45] R Core Team,et al. R: A language and environment for statistical computing. , 2014 .
[46] Tanya M. Teslovich,et al. Discovery and refinement of loci associated with lipid levels , 2013, Nature Genetics.
[47] Margaret A. Pericak-Vance,et al. Identification of a Rare Coding Variant in Complement 3 Associated with Age-related Macular Degeneration , 2013, Nature Genetics.
[48] Sivakumar Gowrisankar,et al. Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration , 2013, Nature Genetics.
[49] Lorna M. Lopez,et al. Meta-Analysis of Genome-Wide Association Studies Identifies Six New Loci for Serum Calcium Concentrations , 2013, PLoS genetics.
[50] Chuong B. Do,et al. A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci , 2013, Nature Genetics.
[51] Thomas Meitinger,et al. Genome-wide meta-analysis identifies new susceptibility loci for migraine , 2013, Nature Genetics.
[52] Paolo Vineis,et al. Genome-wide Association Study Identifies Multiple Risk Loci for Chronic Lymphocytic Leukemia , 2013, Nature Genetics.
[53] Simon G. Coetzee,et al. Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis. , 2013, Gastroenterology.
[54] Marko Hočevar,et al. A variant in FTO shows association with melanoma risk not due to BMI , 2013, Nature Genetics.
[55] P. Mitchell,et al. Differential associations of myopia with major age-related eye diseases: the Singapore Indian Eye Study. , 2013, Ophthalmology.
[56] Tin Aung,et al. Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus , 2013, Nature Genetics.
[57] Suzanne Chambers,et al. A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease. , 2013, Human molecular genetics.
[58] Fabian J Theis,et al. Genome-wide association analyses identify 18 new loci associated with serum urate concentrations , 2012, Nature Genetics.
[59] Peter Kraft,et al. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array , 2013, Nature Genetics.
[60] Chuong B. Do,et al. Genome-Wide Analysis Points to Roles for Extracellular Matrix Remodeling, the Visual Cycle, and Neuronal Development in Myopia , 2012, PLoS genetics.
[61] C. Keilhauer,et al. Age-related macular degeneration and coronary heart disease: evaluation of genetic and environmental associations. , 2012, European journal of medical genetics.
[62] J. Danesh,et al. Large-scale association analysis identifies new risk loci for coronary artery disease , 2013 .
[63] Eli Stahl,et al. High density genetic mapping identifies new susceptibility loci for rheumatoid arthritis , 2012, Nature Genetics.
[64] M. Guardiola,et al. Complement system and small HDL particles are associated with subclinical atherosclerosis in SLE patients. , 2012, Atherosclerosis.
[65] David C. Wilson,et al. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease , 2012, Nature.
[66] Tanya M. Teslovich,et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes , 2012, Nature Genetics.
[67] Colm O'Dushlaine,et al. INRICH: interval-based enrichment analysis for genome-wide association studies , 2012, Bioinform..
[68] I. Heid,et al. Modelling the Genetic Risk in Age-Related Macular Degeneration , 2012, PloS one.
[69] Hideo Tanaka,et al. Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population , 2012, Nature Genetics.
[70] Daniel L. Koller,et al. Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture , 2012, Nature Genetics.
[71] T. Wong,et al. Prevalence of and risk factors for age-related macular degeneration in a multiethnic Asian cohort. , 2012, Archives of ophthalmology.
[72] M. Radic,et al. Autoimmune biomarkers in age-related macular degeneration: a possible role player in disease development and progression. , 2012, Advances in experimental medicine and biology.
[73] Christian Gieger,et al. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma , 2011, Nature Genetics.
[74] Jeffrey E. Lee,et al. Genome-wide association study identifies three new melanoma susceptibility loci , 2011, Nature Genetics.
[75] Jeffrey E. Lee,et al. Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3 , 2011, Nature Genetics.
[76] Christian Gieger,et al. Genome-wide association and large scale follow-up identifies 16 new loci influencing lung function , 2011, Nature Genetics.
[77] Christian Gieger,et al. Genetic Variants in Novel Pathways Influence Blood Pressure and Cardiovascular Disease Risk , 2011, Nature.
[78] Constantin Polychronakos,et al. A Genome-Wide Meta-Analysis of Six Type 1 Diabetes Cohorts Identifies Multiple Associated Loci , 2011, PLoS genetics.
[79] Suzanne Chambers,et al. Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study , 2011, Nature Genetics.
[80] Simon C. Potter,et al. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis , 2011, Nature.
[81] P. Sham,et al. Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases , 2011, Genetic epidemiology.
[82] Yusuke Nakamura,et al. The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population. , 2011, Human molecular genetics.
[83] Steven Gallinger,et al. Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer , 2011, PLoS genetics.
[84] M. Thun,et al. Genome-wide association study identifies new prostate cancer susceptibility loci. , 2011, Human molecular genetics.
[85] P. Elliott,et al. Meta-Analysis of Genome-Wide Association Studies in >80 000 Subjects Identifies Multiple Loci for C-Reactive Protein Levels , 2011, Circulation.
[86] E. Morrison,et al. The Role of High-Density Lipoproteins in Reducing the Risk of Vascular Diseases, Neurogenerative Disorders, and Cancer , 2010, Cholesterol.
[87] R. Mayeux,et al. Association of higher levels of high-density lipoprotein cholesterol in elderly individuals and lower risk of late-onset Alzheimer disease. , 2010, Archives of neurology.
[88] R. Guymer,et al. C-reactive protein levels and complement factor H polymorphism interaction in age-related macular degeneration and its progression. , 2010, Ophthalmology.
[89] Daniel L. Koller,et al. Common genetic determinants of vitamin D insufficiency: a genome-wide association study , 2010, The Lancet.
[90] Uwe Völker,et al. New loci associated with kidney function and chronic kidney disease , 2010, Nature Genetics.
[91] Inês Barroso,et al. Genome-wide association study identifies five loci associated with lung function , 2010, Nature Genetics.
[92] D. Clayton,et al. The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes , 2009, Nature Genetics.
[93] A. Hofman,et al. Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function , 2010, Nature Genetics.
[94] D. Clayton,et al. Genome-wide association study and meta-analysis finds over 40 loci affect risk of type 1 diabetes , 2009, Nature Genetics.
[95] Santa Jeremy Ono,et al. Autoimmunity in retinal degeneration: autoimmune retinopathy and age-related macular degeneration. , 2009, Journal of autoimmunity.
[96] Ali Amin Al Olama,et al. Multiple loci on 8q24 associated with prostate cancer susceptibility , 2009, Nature Genetics.
[97] Ali Amin Al Olama,et al. Identification of seven new prostate cancer susceptibility loci through a genome-wide association study , 2009, Nature Genetics.
[98] Kari Stefansson,et al. Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility , 2009, Nature Genetics.
[99] Yurii S. Aulchenko,et al. Multiple loci associated with indices of renal function and chronic kidney disease , 2009, Nature Genetics.
[100] Vincent Plagnol,et al. Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci , 2008, Nature Genetics.
[101] L. Smeeth,et al. Age-related macular degeneration and complement activation-related diseases: a population-based case-control study. , 2008, Ophthalmology.
[102] Y. Kamatani,et al. Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population , 2008, Nature Genetics.
[103] Emily W. Gower,et al. Hospitalized cardiovascular diseases in neovascular age-related macular degeneration. , 2008, Archives of ophthalmology.
[104] J. Brooks. Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer , 2008 .
[105] J. Carpten,et al. Evidence for two independent prostate cancer risk–associated loci in the HNF1B gene at 17q12 , 2008, Nature Genetics.
[106] R. Klein,et al. Is Age-Related Macular Degeneration Associated with Stroke Among Elderly Americans?§ , 2008, The open ophthalmology journal.
[107] Ali Amin Al Olama,et al. Multiple newly identified loci associated with prostate cancer susceptibility , 2008, Nature Genetics.
[108] Kevin M. Bradley,et al. Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer , 2008, Nature Genetics.
[109] Sharon D. Solomon,et al. Racial differences in the prevalence of age-related macular degeneration: the Salisbury Eye Evaluation (SEE) Project. , 2008, Archives of ophthalmology.
[110] M. Cesari,et al. The aging process and potential interventions to extend life expectancy , 2007, Clinical interventions in aging.
[111] Alan Bensoussan,et al. Use of calcium or calcium in combination with vitamin D supplementation to prevent fractures and bone loss in people aged 50 years and older: a meta-analysis , 2007, The Lancet.
[112] Joseph T. Glessner,et al. A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene , 2007, Nature.
[113] D. Gudbjartsson,et al. Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes , 2007, Nature Genetics.
[114] G. Abecasis,et al. Genetic susceptibility to age-related macular degeneration: a paradigm for dissecting complex disease traits. , 2007, Human molecular genetics.
[115] R. A. Bailey,et al. Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes , 2007, Nature Genetics.
[116] D. Gudbjartsson,et al. Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24 , 2007, Nature Genetics.
[117] R. Klein,et al. Age-related macular degeneration is associated with incident myocardial infarction among elderly Americans. , 2007, Ophthalmology.
[118] R. T. Smith,et al. Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration , 2006, Nature Genetics.
[119] Ronald Klein,et al. A simplified severity scale for age-related macular degeneration: AREDS Report No. 18. , 2005, Archives of ophthalmology.
[120] Jennifer J. Gibson,et al. Pigmentary characteristics and moles in relation to melanoma risk , 2005, International journal of cancer.
[121] R. T. Smith,et al. A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[122] Leslie Hyman,et al. A Simplified Severity Scale for Age-Related Macular Degeneration , 2005 .
[123] B. Munoz,et al. Racial variations in causes of vision loss in nursing homes: The Salisbury Eye Evaluation in Nursing Home Groups (SEEING) Study. , 2004, Archives of ophthalmology.
[124] P. Jong. Prevalence of age-related macular degeneration in the United States. , 2004 .
[125] T. Mack,et al. Skin characteristics and risk of superficial spreading and nodular melanoma (United States) , 2000, Cancer Causes & Control.
[126] Benita J. O’Colmain,et al. Prevalence of age-related macular degeneration in the United States. , 2004, Archives of ophthalmology.
[127] Y. Benjamini,et al. THE CONTROL OF THE FALSE DISCOVERY RATE IN MULTIPLE TESTING UNDER DEPENDENCY , 2001 .
[128] George C. Williams,et al. PLEIOTROPY, NATURAL SELECTION, AND THE EVOLUTION OF SENESCENCE , 1957, Science of Aging Knowledge Environment.
[129] M. C. Leske,et al. Hypertension, cardiovascular disease, and age-related macular degeneration. Age-Related Macular Degeneration Risk Factors Study Group. , 2000, Archives of ophthalmology.