A penile rash in a child with arthritis

A 9-year-old boy presented with 2 weeks of fever; oligoarthritis involving the right elbow, left knee and elbow; and bilateral conjunctivitis. He had a history of typhoid fever 1 year ago, which was treated and resolved. Investigations showed sterile pyuria, with a white blood cell count of 25 cells per high-power field with negative urine culture, suggestive of urethritis. During the admission, he developed painless, psoriasiform plaques with surrounding erythematous borders and scaling on the glans penis (Figure 1). There was no associated urethral discharge or other mucocutaneous lesions, and the palms and soles were uninvolved. Chlamydia and gonorrhea PCR were negative, and syphilis and human immunodeficiency virus serologies were negative. Penile swab bacterial culture and fungal scraping were unremarkable. HLA-B27 was positive. Autoimmune markers, such as rheumatoid factor and antinuclear antibodies, were negative.

[1]  L. Teh,et al.  Circinate balanitis as the presenting symptom of sexually-acquired reactive arthritis: a case report. , 2015, The British journal of general practice : the journal of the Royal College of General Practitioners.

[2]  Ravi Ahluwalia,et al.  Reiter's disease: Circinate balanitis as alone preceding presentation - Successfully treated with pimecrolimus 1% cream , 2015, Indian journal of sexually transmitted diseases and AIDS.

[3]  E. Cinteză,et al.  Postinfectious arthritis in pediatric practice. , 2013, Maedica.

[4]  Jian Hu,et al.  [Reiter's syndrome in children: a clinical analysis of 22 cases]. , 2010, Zhonghua er ke za zhi = Chinese journal of pediatrics.

[5]  F. Medina,et al.  Tacrolimus Therapy for Circinate Balanitis Associated With Reactive Arthritis , 2009, Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases.

[6]  K. Chudomirova,et al.  Clinical tetrad of arthritis, urethritis, conjunctivitis, and mucocutaneous lesions (HLA-B27-associated spondyloarthropathy, Reiter syndrome): report of a case. , 2008, Dermatology online journal.

[7]  D. Thappa,et al.  Circinate pustular psoriasis localized to glans penis mimicking 'circinate balanitis' and responsive to dapsone. , 2008, Indian journal of dermatology, venereology and leprology.

[8]  I. B. Wu,et al.  Reiter's syndrome: the classic triad and more. , 2008, Journal of the American Academy of Dermatology.

[9]  K. Yeh,et al.  Juvenile Reiter's syndrome: a case report. , 2004, Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi.

[10]  Jian Hu,et al.  [Clinical characteristics of children with enthesitis related arthritis]. , 2003, Zhonghua er ke za zhi = Chinese journal of pediatrics.