Pregnancy outcome in patients with β-thalassemia intermedia at two tertiary care centers, in Beirut and Milan

β-thalassemia intermedia (TI) patients can present with a severe clinical disease at 2–6 years of age or remain asymptomatic until adult life. They suffer from mild anemia (hemoglobin (Hb) between 7–10 g/dL), and are usually transfusion independent.[1][1] Pregnancy in these women, whether

[1]  J. Martin,et al.  Births: final data for 2005. , 2007, National vital statistics reports : from the Centers for Disease Control and Prevention, National Center for Health Statistics, National Vital Statistics System.

[2]  E. Vichinsky,et al.  Serum ferritin underestimates liver iron concentration in transfusion independent thalassemia patients as compared to regularly transfused thalassemia and sickle cell patients , 2007, Pediatric blood & cancer.

[3]  M. Cappellini,et al.  Prevalence of thromboembolic events among 8,860 patients with thalassaemia major and intermedia in the Mediterranean area and Iran , 2006, Thrombosis and Haemostasis.

[4]  A. Inati,et al.  Pregnancy in patients with β‐thalassemia intermedia: Outcome of mothers and newborns , 2006 .

[5]  M. Cappellini,et al.  Thalassemia intermedia: revisited. , 2006, Blood cells, molecules & diseases.

[6]  I. Usta,et al.  β‐Thalassemia intermedia and pregnancy: should we anticoagulate? , 2006, Journal of thrombosis and haemostasis : JTH.

[7]  M. Katz,et al.  Maternal anemia during pregnancy is an independent risk factor for low birthweight and preterm delivery. , 2005, European journal of obstetrics, gynecology, and reproductive biology.

[8]  M. Cappellini,et al.  Venous thromboembolism and hypercoagulability in splenectomized patients with thalassaemia intermedia. , 2000, British journal of haematology.

[9]  D. Gemmati,et al.  Thrombotic risk in thalassemic patients. , 1998, Journal of pediatric endocrinology & metabolism : JPEM.

[10]  M. Angastiniotis,et al.  Fertility in female patients with thalassemia. , 1998, Journal of pediatric endocrinology & metabolism : JPEM.

[11]  M. Cappellini,et al.  Thalassemia intermedia. , 1995, Haematologica.

[12]  M. Divon,et al.  Maternal and fetal blood flow velocity waveforms in intrauterine growth retardation. , 1992, Clinical obstetrics and gynecology.