Crystal structures of the Streptomyces coelicolor TetR-like protein ActR alone and in complex with actinorhodin or the actinorhodin biosynthetic precursor (S)-DNPA.
暂无分享,去创建一个
A. Willems | J. Nodwell | K. Tahlan | K. Zhang | M. Junop | A R Willems | K Zhang | K Tahlan | T Taguchi | Z Z Lee | K Ichinose | M S Junop | J R Nodwell | T. Taguchi | K. Ichinose | Z. Z. Lee | Kun-xiao Zhang
[1] M. Schumacher,et al. Structural basis for cooperative DNA binding by two dimers of the multidrug‐binding protein QacR , 2002, The EMBO journal.
[2] W. Hillen,et al. Thermodynamic analysis of tetracycline-mediated induction of Tet repressor by a quantitative methylation protection assay. , 1995, Analytical biochemistry.
[3] Kevin Cowtan,et al. research papers Acta Crystallographica Section D Biological , 2005 .
[4] S. Baumberg,et al. Transcriptional activation of the pathway‐specific regulator of the actinorhodin biosynthetic genes in Streptomyces coelicolor , 2005, Molecular microbiology.
[5] Jie Liang,et al. CASTp: Computed Atlas of Surface Topography of proteins , 2003, Nucleic Acids Res..
[6] J. Caballero,et al. The act cluster contains regulatory and antibiotic export genes, direct targets for translational control by the bldA tRNA gene of streptomyces , 1991, Cell.
[7] Katalin F Medzihradszky,et al. An antibiotic factory caught in action , 2004, Nature Structural &Molecular Biology.
[8] W. Saenger,et al. Tetracycline-chelated Mg2+ ion initiates helix unwinding in Tet repressor induction. , 1999, Biochemistry.
[9] J. Caballero,et al. Transcriptional organization and regulation of an antibiotic export complex in the producing Streptomyces culture , 1991, Molecular and General Genetics MGG.
[10] M. Schumacher,et al. Structural Mechanisms of QacR Induction and Multidrug Recognition , 2001, Science.
[11] G. Murshudov,et al. Refinement of macromolecular structures by the maximum-likelihood method. , 1997, Acta crystallographica. Section D, Biological crystallography.
[12] C. Hutchinson,et al. Regulation of daunorubicin production in Streptomyces peucetius by the dnrR2 locus , 1995, Journal of bacteriology.
[13] B. Barrell,et al. Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2) , 2002, Nature.
[14] Shiou-Chuan Tsai,et al. Structural Analysis of Actinorhodin Polyketide Ketoreductase: Cofactor Binding and Substrate Specificity , 2004, Biochemistry.
[15] A. Álvarez-Morales,et al. In Pseudomonas syringae pv. phaseolicola, Expression of the argK Gene, Encoding the Phaseolotoxin-Resistant Ornithine Carbamoyltransferase, Is Regulated Indirectly by Temperature and Directly by a Precursor Resembling Carbamoylphosphate , 2004, Journal of bacteriology.
[16] A. Vagin,et al. MOLREP: an Automated Program for Molecular Replacement , 1997 .
[17] W. Saenger,et al. Structure of the Tet repressor-tetracycline complex and regulation of antibiotic resistance. , 1994, Science.
[18] F. Cordes,et al. Conformational changes of the Tet repressor induced by tetracycline trapping. , 1998, Journal of molecular biology.
[19] J. Ramos,et al. Crystal Structures of Multidrug Binding Protein TtgR in Complex with Antibiotics and Plant Antimicrobials , 2007, Journal of molecular biology.
[20] Raquel Tobes,et al. The TetR Family of Transcriptional Repressors , 2005, Microbiology and Molecular Biology Reviews.
[21] W. Reznikoff,et al. Purification of the TET repressor and TET operator from the transposon Tn10 and characterization of their interaction. , 1982, The Journal of biological chemistry.
[22] C. Dempsey,et al. Solution structure of the actinorhodin polyketide synthase acyl carrier protein from Streptomyces coelicolor A3(2). , 1997, Biochemistry.
[23] D. Hughes,et al. Sampling the Antibiotic Resistome , 2006, Science.
[24] J Davies,et al. Aminoglycoside antibiotic-inactivating enzymes in actinomycetes similar to those present in clinical isolates of antibiotic-resistant bacteria. , 1973, Proceedings of the National Academy of Sciences of the United States of America.
[25] Y. Ebizuka,et al. A New Mode of Stereochemical Control Revealed by Analysis of the Biosynthesis of Dihydrogranaticin in Streptomyces violaceoruber Tü22 , 2001 .
[26] W. Saenger,et al. The complex formed between Tet repressor and tetracycline-Mg2+ reveals mechanism of antibiotic resistance. , 1995 .
[27] Tsutomu Watanabe. THE ORIGIN OF R FACTORS * , 1971 .
[28] L. Dijkhuizen,et al. Production of actinorhodin-related "blue pigments" by Streptomyces coelicolor A3(2) , 1996, Journal of bacteriology.
[29] M. Walker,et al. Streptomycin biosynthesis and metabolism. Enzymatic phosphorylation of dihydrostreptobiosamine moieties of dihydro-streptomycin-(streptidino) phosphate and dihydrostreptomycin by Streptomyces extracts. , 1970, The Journal of biological chemistry.
[30] J. Pflugrath,et al. The finer things in X-ray diffraction data collection. , 1999, Acta crystallographica. Section D, Biological crystallography.
[31] R J Read,et al. Crystallography & NMR system: A new software suite for macromolecular structure determination. , 1998, Acta crystallographica. Section D, Biological crystallography.
[32] Yoshiyuki Sakaki,et al. Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis , 2003, Nature Biotechnology.
[33] W. Delano. The PyMOL Molecular Graphics System , 2002 .
[34] W Hillen,et al. Differential regulation of the Tn10‐encoded tetracycline resistance genes tetA and tetR by the tandem tet operators O1 and O2. , 1988, The EMBO journal.
[35] D. Hopwood. How do antibiotic‐producing bacteria ensure their self‐resistance before antibiotic biosynthesis incapacitates them? , 2007, Molecular microbiology.
[36] U. Baumann,et al. Regulation of the Dha Operon of Lactococcus lactis , 2006, Journal of Biological Chemistry.
[37] Hao-Tian Jiang,et al. Feedback regulation of doxorubicin biosynthesis in Streptomyces peucetius. , 2006, Research in microbiology.
[38] W. Reznikoff,et al. Overlapping divergent promoters control expression of Tn10 tetracycline resistance. , 1983, Gene.
[39] W. Hillen,et al. Mechanisms underlying expression of Tn10 encoded tetracycline resistance. , 1994, Annual review of microbiology.
[40] S. Oliver,et al. An integrated approach to studying regulation of production of the antibiotic methylenomycin by Streptomyces coelicolor A3(2) , 1992, Journal of bacteriology.
[41] W. Saenger,et al. Structural basis of gene regulation by the tetracycline inducible Tet repressor–operator system , 2000, Nature Structural Biology.
[42] Randy J Read,et al. Electronic Reprint Biological Crystallography Phenix: Building New Software for Automated Crystallographic Structure Determination Biological Crystallography Phenix: Building New Software for Automated Crystallographic Structure Determination , 2022 .
[43] John Crosby,et al. The crystal structure of the actIII actinorhodin polyketide reductase: proposed mechanism for ACP and polyketide binding. , 2004, Structure.
[44] D. Hopwood,et al. Chemical characterisation of disruptants of the Streptomyces coelicolor A3(2) actVI genes involved in actinorhodin biosynthesis. , 2000, The Journal of antibiotics.
[45] P. Adams,et al. Substructure search procedures for macromolecular structures. , 2003, Acta crystallographica. Section D, Biological crystallography.
[46] C. Locht,et al. Structure of EthR in a ligand bound conformation reveals therapeutic perspectives against tuberculosis. , 2004, Molecular cell.
[47] A. Miele,et al. The structure of ActVA‐Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis , 2003, The EMBO journal.
[48] W A Hendrickson,et al. Selenomethionyl proteins produced for analysis by multiwavelength anomalous diffraction (MAD): a vehicle for direct determination of three‐dimensional structure. , 1990, The EMBO journal.
[49] J. Caballero,et al. Organisation and functions of the actV A region of the actinorhodin biosynthetic gene cluster of Streptomyces coelicolor , 1991, Molecular and General Genetics MGG.