What can asymmetrical cell snakes do?

CTP synthase (CTPS), the rate-limiting enzyme of de novo CTP synthesis, forms the cytoophidium (meaning ’cell snake’ in Greek; cytoophidia as plural) in many types of cells. [1] These cell snakes are dynamic,reversible,andconsistofcorrectlyfoldedproteins.Dozensof cytoophidium-forming proteins have been identified in several organ-isms across prokaryotes and eukaryotes. [2] Cytoophidium assembly is controlledbyligandbinding,post-translationalmodifications,pHvalue and molecular crowding. [3] Therefore, the formation of cytoophidia may reflect the cell status and also influence cell behaviours.