Rodent models of heart failure: an updated review

[1]  J. Korinek,et al.  Variable phenotype in murine transverse aortic constriction. , 2012, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.

[2]  Qin M. Chen,et al.  p21(WAF1/Cip1/Sdi1) knockout mice respond to doxorubicin with reduced cardiotoxicity. , 2011, Toxicology and applied pharmacology.

[3]  D. Kass,et al.  Bi-modal dose-dependent cardiac response to tetrahydrobiopterin in pressure-overload induced hypertrophy and heart failure. , 2011, Journal of molecular and cellular cardiology.

[4]  D. Sorescu,et al.  Diastolic dysfunction is associated with cardiac fibrosis in the senescence-accelerated mouse. , 2011, American journal of physiology. Heart and circulatory physiology.

[5]  Zhiqiang Wang,et al.  [Comparative study on repairing rabbit radius segmental defects with two different proportions of chitosan combined with allogeneic morselized bone]. , 2011, Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery.

[6]  M. Yano,et al.  Alterations in adhesion junction precede gap junction remodelling during the development of heart failure in cardiomyopathic hamsters. , 2011, Cardiovascular research.

[7]  W. Paulus,et al.  Distinct mechanisms for diastolic dysfunction in diabetes mellitus and chronic pressure-overload , 2011, Basic Research in Cardiology.

[8]  R. Evans,et al.  Effects of chronic sympatho-inhibition on renal excretory function in renovascular hypertension , 2011, Journal of hypertension.

[9]  Peter P. Liu,et al.  Diastolic heart failure: progress, treatment challenges, and prevention. , 2011, The Canadian journal of cardiology.

[10]  Angelo Auricchio,et al.  What are the costs of heart failure? , 2011, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[11]  V. Regitz-Zagrosek,et al.  Differential Cardiac Remodeling in Preload Versus Afterload , 2010, Circulation.

[12]  C. Lim,et al.  Mechanisms of anthracycline cardiac injury: can we identify strategies for cardioprotection? , 2010, Progress in cardiovascular diseases.

[13]  M. Rossi,et al.  Matrix metalloproteinase inhibition improves cardiac dysfunction and remodeling in 2-kidney, 1-clip hypertension. , 2010, Journal of cardiac failure.

[14]  T. Shirasawa,et al.  Model mice for tissue‐specific deletion of the manganese superoxide dismutase gene , 2010, Geriatrics & gerontology international.

[15]  Y. Arbel,et al.  Large animal models for diastolic dysfunction and diastolic heart failure-a review of the literature. , 2010, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.

[16]  D. Mozaffarian,et al.  Heart disease and stroke statistics--2010 update: a report from the American Heart Association. , 2010, Circulation.

[17]  S. Dikalov,et al.  Uncoupled Cardiac Nitric Oxide Synthase Mediates Diastolic Dysfunction , 2010, Circulation.

[18]  João Ferreira-Martins,et al.  Anthracycline Cardiomyopathy Is Mediated by Depletion of the Cardiac Stem Cell Pool and Is Rescued by Restoration of Progenitor Cell Function , 2010, Circulation.

[19]  Gen Suzuki,et al.  Intramuscular VEGF repairs the failing heart: role of host-derived growth factors and mobilization of progenitor cells. , 2009, American journal of physiology. Regulatory, integrative and comparative physiology.

[20]  D. Kass,et al.  Adverse ventricular remodeling and exacerbated NOS uncoupling from pressure-overload in mice lacking the beta3-adrenoreceptor. , 2009, Journal of molecular and cellular cardiology.

[21]  A. Curcio,et al.  Beta1-adrenergic receptors stimulate cardiac contractility and CaMKII activation in vivo and enhance cardiac dysfunction following myocardial infarction. , 2009, American journal of physiology. Heart and circulatory physiology.

[22]  S. Houser,et al.  Novel experimental model of pressure overload hypertrophy in rats. , 2009, The Journal of surgical research.

[23]  Tong Zhang,et al.  Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. , 2009, The Journal of clinical investigation.

[24]  R. Patten,et al.  Small animal models of heart failure: development of novel therapies, past and present. , 2009, Circulation. Heart failure.

[25]  Jeffrey Robbins,et al.  With great power comes great responsibility: using mouse genetics to study cardiac hypertrophy and failure. , 2009, Journal of molecular and cellular cardiology.

[26]  R. Hajjar,et al.  Rescue of Ca2+ overload-induced left ventricular dysfunction by targeted ablation of phospholamban. , 2009, American journal of physiology. Heart and circulatory physiology.

[27]  P. Ponikowski,et al.  Inflammation as a therapeutic target in heart failure? A scientific statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology , 2009, European journal of heart failure.

[28]  M. Štěrba,et al.  Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron , 2009, Pharmacological reports : PR.

[29]  M. Crespo,et al.  Early pathophysiological alterations in experimental cardiomyopathy: the Syrian cardiomyopathic hamster. , 2008, Puerto Rico health sciences journal.

[30]  P. S. M. Prince,et al.  Preventive effect of S-allylcysteine on membrane-bound enzymes and glycoproteins in normal and isoproterenol-induced cardiac toxicity in male Wistar rats. , 2008, Basic & clinical pharmacology & toxicology.

[31]  J. Zweier,et al.  Cardiac Myocyte–Specific Expression of Inducible Nitric Oxide Synthase Protects Against Ischemia/Reperfusion Injury by Preventing Mitochondrial Permeability Transition , 2008, Circulation.

[32]  M. Koutsilieris,et al.  In vivo models for heart failure research. , 2008, In vivo.

[33]  D. Atar,et al.  ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008 ‡ , 2008, European journal of heart failure.

[34]  Pál Pacher,et al.  Measurement of cardiac function using pressure–volume conductance catheter technique in mice and rats , 2008, Nature Protocols.

[35]  Y. Jing,et al.  Proteomic analysis of left ventricular diastolic dysfunction hearts in renovascular hypertensive rats. , 2008, International journal of cardiology.

[36]  A. Leite-Moreira,et al.  Myocardial effects of endothelin-1. , 2008, Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology.

[37]  M. Koutsilieris,et al.  Molecular diagnosis of the viral component in cardiomyopathies: pathophysiological, clinical and therapeutic implications , 2008 .

[38]  D. Kass,et al.  High-Dose Folic Acid Pretreatment Blunts Cardiac Dysfunction During Ischemia Coupled to Maintenance of High-Energy Phosphates and Reduces Postreperfusion Injury , 2008, Circulation.

[39]  H. Ly,et al.  Reversal of cardiac dysfunction after long-term expression of SERCA2a by gene transfer in a pre-clinical model of heart failure. , 2008, Journal of the American College of Cardiology.

[40]  J. Grzyb,et al.  Wide-spread myocardial remodeling after acute myocardial infarction in rat. Features for heart failure progression. , 2008, Vascular pharmacology.

[41]  E. Abel,et al.  Molecular mechanisms for myocardial mitochondrial dysfunction in the metabolic syndrome. , 2008, Clinical science.

[42]  C. Delgado,et al.  LA419, a Novel Nitric Oxide Donor, Prevents Pathological Cardiac Remodeling in Pressure-Overloaded Rats Via Endothelial Nitric Oxide Synthase Pathway Regulation , 2007, Hypertension.

[43]  C. Patterson,et al.  Characterization of a model to independently study regression of ventricular hypertrophy. , 2007, The Journal of surgical research.

[44]  W. Piwowarska,et al.  Diabetes-specific cardiomyopathy in type 1 diabetes mellitus: no evidence for its occurrence in the era of intensive insulin therapy. , 2007, European Heart Journal.

[45]  Xiaoming Sheng,et al.  Mitochondrial Energetics in the Heart in Obesity-Related Diabetes , 2007, Diabetes.

[46]  B. Fernández,et al.  Atrial natriuretic peptide behaviour and myocyte hypertrophic profile in combined pressure and volume-induced cardiac hypertrophy , 2007, Journal of hypertension.

[47]  E. Konofagou,et al.  Myocardial elastography at both high temporal and spatial resolution for the detection of infarcts. , 2007, Ultrasound in medicine & biology.

[48]  K. Rajewsky,et al.  Vagaries of conditional gene targeting , 2007, Nature Immunology.

[49]  E. Abel,et al.  Diabetic cardiomyopathy revisited. , 2007, Circulation.

[50]  Joseph S Janicki,et al.  Inhibition of matrix metalloproteinase activity by ACE inhibitors prevents left ventricular remodeling in a rat model of heart failure. , 2007, American journal of physiology. Heart and circulatory physiology.

[51]  G. Minotti,et al.  An introduction to the metabolic determinants of anthracycline cardiotoxicity , 2007, Cardiovascular Toxicology.

[52]  G. Takemura,et al.  Doxorubicin-induced cardiomyopathy from the cardiotoxic mechanisms to management. , 2007, Progress in cardiovascular diseases.

[53]  P. Herijgers,et al.  Type II diabetic mice exhibit contractile dysfunction but maintain cardiac output by favourable loading conditions , 2006, European journal of heart failure.

[54]  Y. Kihara,et al.  Angiotensin II, oxidative stress, and extracellular matrix degradation during transition to LV failure in rats with hypertension. , 2006, Journal of molecular and cellular cardiology.

[55]  D. Butterfield,et al.  Redox proteomic identification of oxidized cardiac proteins in adriamycin-treated mice. , 2006, Free radical biology & medicine.

[56]  P. Steendijk,et al.  Characterization of right ventricular function after monocrotaline-induced pulmonary hypertension in the intact rat. , 2006, American journal of physiology. Heart and circulatory physiology.

[57]  M. Andrassy,et al.  Cardiac Troponin I but Not Cardiac Troponin T Induces Severe Autoimmune Inflammation in the Myocardium , 2006, Circulation.

[58]  Brian Rodrigues,et al.  Role of changes in cardiac metabolism in development of diabetic cardiomyopathy. , 2006, American journal of physiology. Heart and circulatory physiology.

[59]  John Miller,et al.  Myocardial expression of survivin, an apoptosis inhibitor, in aging and heart failure. An experimental study in the spontaneously hypertensive rat. , 2006, International journal of cardiology.

[60]  A. Yao,et al.  Upregulated neurohumoral factors are associated with left ventricular remodeling and poor prognosis in rats with monocrotaline-induced pulmonary arterial hypertension. , 2006, Circulation journal : official journal of the Japanese Circulation Society.

[61]  P. Carmeliet,et al.  Inhibition of Urokinase-Type Plasminogen Activator or Matrix Metalloproteinases Prevents Cardiac Injury and Dysfunction During Viral Myocarditis , 2006, Circulation.

[62]  Ji Myoung Kim,et al.  PICOT Inhibits Cardiac Hypertrophy and Enhances Ventricular Function and Cardiomyocyte Contractility , 2006, Circulation research.

[63]  T. Kato,et al.  Attenuation of cardiac dysfunction by a PPAR-alpha agonist is associated with down-regulation of redox-regulated transcription factors. , 2006, Journal of molecular and cellular cardiology.

[64]  L. Rochette,et al.  Dissociation between vascular oxidative stress and cardiovascular function in Wistar Kyoto and spontaneously hypertensive rats. , 2006, Vascular pharmacology.

[65]  P. S. M. Prince,et al.  Preventive effect of S-allylcysteine on lipid peroxides and antioxidants in normal and isoproterenol-induced cardiotoxicity in rats: a histopathological study. , 2006, Toxicology.

[66]  H. Seo,et al.  Effects of KR-31378, a novel ATP-sensitive potassium channel activator, on hypertrophy of H9c2 cells and on cardiac dysfunction in rats with congestive heart failure. , 2006, European journal of pharmacology.

[67]  M. Olandoski,et al.  Cell transplantation after the coculture of skeletal myoblasts and mesenchymal stem cells in the regeneration of the myocardium scar: an experimental study in rats. , 2006, Transplantation proceedings.

[68]  A. Leite-Moreira,et al.  Impaired Response to ETB Receptor Stimulation in Heart Failure: Functional Evidence of Endocardial Endothelial Dysfunction? , 2006, Experimental biology and medicine.

[69]  J. Grobe,et al.  Chronic angiotensin-(1-7) prevents cardiac fibrosis in DOCA-salt model of hypertension. , 2006, American journal of physiology. Heart and circulatory physiology.

[70]  D. Lachance,et al.  Gender-related differences in left ventricular remodeling in chronic severe aortic valve regurgitation in rats. , 2006, The Journal of heart valve disease.

[71]  D. Burkhoff,et al.  Development of Heart Failure in Chronic Hypertensive Dahl Rats: Focus on Heart Failure With Preserved Ejection Fraction , 2006, Hypertension.

[72]  A. Leite-Moreira,et al.  Current perspectives in diastolic dysfunction and diastolic heart failure , 2006, Heart.

[73]  G. Takemura,et al.  Autophagic Degeneration and Death of Cardiomyocytes in Heart Failure , 2006, Autophagy.

[74]  J. Joseph,et al.  Effect of long-term hyperhomocysteinemia on myocardial structure and function in hypertensive rats. , 2006, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.

[75]  G. Breithardt,et al.  G-CSF/SCF reduces inducible arrhythmias in the infarcted heart potentially via increased connexin43 expression and arteriogenesis , 2006, The Journal of experimental medicine.

[76]  M. Völkers,et al.  S100A1 gene therapy preserves in vivo cardiac function after myocardial infarction. , 2005, Molecular therapy : the journal of the American Society of Gene Therapy.

[77]  U. Walker,et al.  Tissue‐specific mtDNA lesions and radical‐associated mitochondrial dysfunction in human hearts exposed to doxorubicin , 2005, The Journal of pathology.

[78]  N. Vaziri,et al.  Hypertension induced by aortic coarctation above the renal arteries is associated with immune cell infiltration of the kidneys. , 2005, American journal of hypertension.

[79]  D. Su,et al.  Synergistic effects of atenolol and amlodipine for lowering and stabilizing blood pressure in 2K1C renovascular hypertensive rats , 2005, Acta Pharmacologica Sinica.

[80]  J. Rottman,et al.  Organ-specific roles for transcription factor NF-kappaB in reovirus-induced apoptosis and disease. , 2005, The Journal of clinical investigation.

[81]  C. Wahl-Schott,et al.  Increased SR Ca2+ cycling contributes to improved contractile performance in SERCA2a-overexpressing transgenic rats. , 2005, Cardiovascular research.

[82]  P. Allen,et al.  Cardiac gene expression profiling provides evidence for cytokinopathy as a molecular mechanism in Chagas' disease cardiomyopathy. , 2005, The American journal of pathology.

[83]  N. Dhalla,et al.  Upregulation of β-adrenergic receptors in heart failure due to volume overload , 2005 .

[84]  Xuyang Peng,et al.  The cardiotoxicology of anthracycline chemotherapeutics: translating molecular mechanism into preventative medicine. , 2005, Molecular interventions.

[85]  B. Ylstra,et al.  Microarray analysis reveals pivotal divergent mRNA expression profiles early in the development of either compensated ventricular hypertrophy or heart failure. , 2005, Physiological genomics.

[86]  N. Dhalla,et al.  A comparative serial echocardiographic analysis of cardiac structure and function in rats subjected to pressure or volume overload. , 2005, Journal of molecular and cellular cardiology.

[87]  J. Chachques,et al.  Animal models of heart failure: what is new? , 2005, The Annals of thoracic surgery.

[88]  M. Anderson.  Calmodulin kinase signaling in heart: an intriguing candidate target for therapy of myocardial dysfunction and arrhythmias. , 2005, Pharmacology & therapeutics.

[89]  E. El-demerdash,et al.  Probucol attenuates oxidative stress and energy decline in isoproterenol-induced heart failure in rat. , 2005, Pharmacological research.

[90]  C. Szabó,et al.  Poly(ADP-Ribose) Polymerase Promotes Cardiac Remodeling, Contractile Failure, and Translocation of Apoptosis-Inducing Factor in a Murine Experimental Model of Aortic Banding and Heart Failure , 2005, Journal of Pharmacology and Experimental Therapeutics.

[91]  N. V. van Riel,et al.  Poly(ADP-ribose) polymerase regulates myocardial calcium handling in doxorubicin-induced heart failure. , 2005, Biochemical pharmacology.

[92]  Zhongjie Sun,et al.  Historic perspectives and recent advances in major animal models of Hypertension , 2005, Acta Pharmacologica Sinica.

[93]  C. H. Conrad,et al.  Heart failure after long-term supravalvular aortic constriction in rats. , 2005, American journal of hypertension.

[94]  D. Kass,et al.  Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy , 2005, Nature Medicine.

[95]  M. Bohlooly-y,et al.  Murine models for the study of congestive heart failure: Implications for understanding molecular mechanisms and for drug discovery. , 2004, Journal of pharmacological and toxicological methods.

[96]  A. Protter,et al.  p38α Mitogen-Activated Protein Kinase Inhibition Improves Cardiac Function and Reduces Myocardial Damage in Isoproterenol-Induced Acute Myocardial Injury in Rats , 2004, Journal of cardiovascular pharmacology.

[97]  G. Takemura,et al.  Critical Roles for the Fas/Fas Ligand System in Postinfarction Ventricular Remodeling and Heart Failure , 2004, Circulation research.

[98]  S. Niwano,et al.  Structural and electrical ventricular remodeling in rat acute myocarditis and subsequent heart failure. , 2004, Cardiovascular research.

[99]  E. Schlenker,et al.  Effects of long-term captopril and L-arginine treatment on ventilation and blood pressure in obese male SHHF rats. , 2004, Journal of applied physiology.

[100]  S. Mccune,et al.  Effect of Male Sex and Obesity on Platelet Arachidonic Acid in Spontaneous Hypertensive Heart Failure Rats , 2004, Experimental biology and medicine.

[101]  P. Singal,et al.  Cytokines are not upregulated in adriamycin-induced cardiomyopathy and heart failure. , 2004, Journal of molecular and cellular cardiology.

[102]  I. Yamaguchi,et al.  Myocardial fibrosis and diastolic dysfunction in deoxycorticosterone acetate-salt hypertensive rats is ameliorated by the peroxisome proliferator-activated receptor-alpha activator fenofibrate, partly by suppressing inflammatory responses associated with the nuclear factor-kappa-B pathway. , 2004, Journal of the American College of Cardiology.

[103]  A. Sakamoto.  Electrical and ionic abnormalities in the heart of cardiomyopathic hamsters: In quest of a new paradigm for cardiac failure and lethal arrhythmia , 2004, Molecular and Cellular Biochemistry.

[104]  D. Mann,et al.  Cyclooxygenase-2 Inhibitor Treatment Improves Left Ventricular Function and Mortality in a Murine Model of Doxorubicin-Induced Heart Failure , 2004, Circulation.

[105]  G. Isenberg,et al.  Altered Calcium Handling Is Critically Involved in the Cardiotoxic Effects of Chronic &bgr;-Adrenergic Stimulation , 2004, Circulation.

[106]  Xinxin Guo,et al.  Anthracyclines Induce Calpain-dependent Titin Proteolysis and Necrosis in Cardiomyocytes* , 2004, Journal of Biological Chemistry.

[107]  M. Picard,et al.  Influence of sex on ventricular remodeling after myocardial infarction in mice. , 2003, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

[108]  S. Meng,et al.  Renal and vascular oxidative stress and salt-sensitivity of arterial pressure. , 2003, Acta physiologica Scandinavica.

[109]  G. Fink,et al.  Endothelin-1 Stimulates Arterial VCAM-1 Expression Via NADPH Oxidase-Derived Superoxide in Mineralocorticoid Hypertension , 2003, Hypertension.

[110]  U. Eriksson,et al.  Phosphoinositide 3-Kinase &ggr;–Deficient Mice Are Protected From Isoproterenol-Induced Heart Failure , 2003 .

[111]  R. Schwartz,et al.  Mutations in the muscle LIM protein and alpha-actinin-2 genes in dilated cardiomyopathy and endocardial fibroelastosis. , 2003, Molecular genetics and metabolism.

[112]  E. Abel,et al.  Minimally invasive aortic banding in mice: effects of altered cardiomyocyte insulin signaling during pressure overload. , 2003, American journal of physiology. Heart and circulatory physiology.

[113]  A. Takeshita,et al.  Targeted deletion of MMP-2 attenuates early LV rupture and late remodeling after experimental myocardial infarction. , 2003, American journal of physiology. Heart and circulatory physiology.

[114]  Y. Yoshikawa,et al.  Beneficial effects of angiotensin-converting enzyme inhibition on sarcoplasmic reticulum function in the failing heart of the Dahl rat. , 2003, Circulation journal : official journal of the Japanese Circulation Society.

[115]  E. Kranias,et al.  Calcium: Phospholamban: a crucial regulator of cardiac contractility , 2003, Nature Reviews Molecular Cell Biology.

[116]  E. Schiffrin,et al.  Role of endothelins in animal models of hypertension: focus on cardiovascular protection. , 2003, Canadian journal of physiology and pharmacology.

[117]  M. Hauer-Jensen,et al.  Hyperhomocysteinemia leads to pathological ventricular hypertrophy in normotensive rats. , 2003, American journal of physiology. Heart and circulatory physiology.

[118]  Q. Liang,et al.  Reengineering Inducible Cardiac-Specific Transgenesis With an Attenuated Myosin Heavy Chain Promoter , 2003, Circulation research.

[119]  A. Dart,et al.  Altered calcium transient and development of hypertrophy in β2‐adrenoceptor overexpressing mice with and without pressure overload , 2003, European journal of heart failure.

[120]  Ulrike Mende,et al.  Dilated Cardiomyopathy and Heart Failure Caused by a Mutation in Phospholamban , 2003, Science.

[121]  W. Tang,et al.  Pathophysiology of congestive heart failure. , 2003, Reviews in cardiovascular medicine.

[122]  N. Dhalla,et al.  Characterization of cardiac hypertrophy and heart failure due to volume overload in the rat. , 2003, Journal of applied physiology.

[123]  V. Shusterman,et al.  Calcium-dependent arrhythmias in transgenic mice with heart failure. , 2003, American journal of physiology. Heart and circulatory physiology.

[124]  L. Fink,et al.  Hyperhomocysteinemia leads to adverse cardiac remodeling in hypertensive rats. , 2002, American journal of physiology. Heart and circulatory physiology.

[125]  Douglas L Mann,et al.  Inflammatory mediators and the failing heart: past, present, and the foreseeable future. , 2002, Circulation research.

[126]  S. Neubauer,et al.  Feedback Inhibition of Catecholamine Release by Two Different &agr;2-Adrenoceptor Subtypes Prevents Progression of Heart Failure , 2002, Circulation.

[127]  E. Blasi,et al.  Structural, functional, and molecular characterization of the SHHF model of heart failure. , 2002, American journal of physiology. Heart and circulatory physiology.

[128]  A. Matsumori,et al.  Left ventricular pressure-volume relationship in a murine model of congestive heart failure due to acute viral myocarditis. , 2002, Journal of the American College of Cardiology.

[129]  M. Yano,et al.  FKBP12.6-Mediated Stabilization of Calcium-Release Channel (Ryanodine Receptor) as a Novel Therapeutic Strategy Against Heart Failure , 2002, Circulation.

[130]  Y. Taniyama,et al.  Elevated myocardial Akt signaling ameliorates doxorubicin-induced congestive heart failure and promotes heart growth. , 2002, Journal of molecular and cellular cardiology.

[131]  M. Kohno,et al.  Perindopril Effect on Uncoupling Protein and Energy Metabolism in Failing Rat Hearts , 2002, Hypertension.

[132]  Haruhiko Koseki,et al.  Model mice for tissue-specific deletion of the manganese superoxide dismutase (MnSOD) gene. , 2002, Biochemical and biophysical research communications.

[133]  V. Shusterman,et al.  Strain-specific patterns of autonomic nervous system activity and heart failure susceptibility in mice. , 2002, American journal of physiology. Heart and circulatory physiology.

[134]  M. Pfeffer,et al.  New Therapeutic Options in Congestive Heart Failure: Part II , 2002, Circulation.

[135]  N. Dalton,et al.  Progressive heart failure after myocardial infarction in mice , 2002, Basic Research in Cardiology.

[136]  Marc A Pfeffer,et al.  New therapeutic options in congestive heart failure: Part I. , 2002, Circulation.

[137]  A. Meiracker.  Endothelins and venous tone in DOCA-salt hypertension. , 2002 .

[138]  D. Marchuk,et al.  Genetic Modifier Loci Affecting Survival and Cardiac Function in Murine Dilated Cardiomyopathy , 2002, Circulation.

[139]  Mark A. Magnuson,et al.  Oestrogen protects FKBP12.6 null mice from cardiac hypertrophy , 2002, Nature.

[140]  D. Brutsaert,et al.  New concepts in diastolic dysfunction and diastolic heart failure: Part I: diagnosis, prognosis, and measurements of diastolic function. , 2002, Circulation.

[141]  S. Cherry,et al.  Cardiac Myocyte-Specific Excision of the &bgr;1 Integrin Gene Results in Myocardial Fibrosis and Cardiac Failure , 2002, Circulation research.

[142]  M. Krieger,et al.  Loss of SR-BI Expression Leads to the Early Onset of Occlusive Atherosclerotic Coronary Artery Disease, Spontaneous Myocardial Infarctions, Severe Cardiac Dysfunction, and Premature Death in Apolipoprotein E-Deficient Mice , 2002, Circulation research.

[143]  A. Matsumori,et al.  Evidence for a Role of Mast Cells in the Evolution to Congestive Heart Failure , 2002, The Journal of experimental medicine.

[144]  J. Bauer,et al.  Intracellular distribution of peroxynitrite during doxorubicin cardiomyopathy: evidence for selective impairment of myofibrillar creatine kinase , 2002, British journal of pharmacology.

[145]  M. Entman,et al.  Heart failure and greater infarct expansion in middle-aged mice: a relevant model for postinfarction failure. , 2002, American journal of physiology. Heart and circulatory physiology.

[146]  J. Towbin,et al.  The failing heart , 2002, Nature.

[147]  M. Lohse,et al.  Early impairment of calcium handling and altered expression of junctin in hearts of mice overexpressing the β1−adrenergic receptor , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[148]  E. Olson,et al.  Dilated Cardiomyopathy and Sudden Death Resulting From Constitutive Activation of Protein Kinase A , 2001, Circulation research.

[149]  K. Chien,et al.  Absence of pressure overload induced myocardial hypertrophy after conditional inactivation of Gαq/Gα11 in cardiomyocytes , 2001, Nature Medicine.

[150]  H. Yamawaki,et al.  Chronic effect of doxorubicin on vascular endothelium assessed by organ culture study. , 2001, Life sciences.

[151]  Z. Abassi,et al.  Evaluation of Atrial Natriuretic Peptide and Brain Natriuretic Peptide in Atrial Granules of Rats with Experimental Congestive Heart Failure , 2001, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[152]  R. Dietz,et al.  A new model of congestive heart failure in the mouse due to chronic volume overload , 2001, European journal of heart failure.

[153]  M. Cowie,et al.  The epidemiological features of heart failure in developing countries: a review of the literature. , 2001, International journal of cardiology.

[154]  W. Manning,et al.  Transgenic Expression of Sarcoplasmic Reticulum Ca2+ ATPase Modifies the Transition From Hypertrophy to Early Heart Failure , 2001, Circulation research.

[155]  K. Saupe,et al.  Exercise Training Attenuates Age-Associated Diastolic Dysfunction in Rats , 2001, Circulation.

[156]  M. Crackower,et al.  Temporally Regulated and Tissue-Specific Gene Manipulations in the Adult and Embryonic Heart Using a Tamoxifen-Inducible Cre Protein , 2001, Circulation research.

[157]  D. Livingston,et al.  Self-excising retroviral vectors encoding the Cre recombinase overcome Cre-mediated cellular toxicity. , 2001, Molecular cell.

[158]  G. Dorn,et al.  Superinhibition of Sarcoplasmic Reticulum Function by Phospholamban Induces Cardiac Contractile Failure* , 2001, The Journal of Biological Chemistry.

[159]  E. Schiffrin.  Role of endothelin-1 in hypertension and vascular disease. , 2001, American journal of hypertension.

[160]  N. Rose,et al.  From infection to autoimmunity. , 2001, Journal of autoimmunity.

[161]  R. Lefkowitz,et al.  Cardiac βARK1 inhibition prolongs survival and augments β blocker therapy in a mouse model of severe heart failure , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[162]  Richard T. Lee,et al.  Electrophysiological characterization of murine myocardial ischemia and infarction , 2001, Basic Research in Cardiology.

[163]  A. Marian,et al.  The molecular genetic basis for hypertrophic cardiomyopathy. , 2001, Journal of molecular and cellular cardiology.

[164]  G. Dorn,et al.  Rescue of Contractile Parameters and Myocyte Hypertrophy in Calsequestrin Overexpressing Myocardium by Phospholamban Ablation* , 2001, The Journal of Biological Chemistry.

[165]  J. Seidman,et al.  The Genetic Basis for Cardiomyopathy from Mutation Identification to Mechanistic Paradigms , 2001, Cell.

[166]  G. Dorn,et al.  Interactions Between Phospholamban and &bgr;-Adrenergic Drive May Lead to Cardiomyopathy and Early Mortality , 2001, Circulation.

[167]  Shokei Kim,et al.  Effects of Combination of ACE Inhibitor and Angiotensin Receptor Blocker on Cardiac Remodeling, Cardiac Function, and Survival in Rat Heart Failure , 2001, Circulation.

[168]  G. Váradi,et al.  A Ca2+-Dependent Transgenic Model of Cardiac Hypertrophy: A Role for Protein Kinase C&agr; , 2001 .

[169]  G. Jennings,et al.  Age-dependent cardiomyopathy and heart failure phenotype in mice overexpressing beta(2)-adrenergic receptors in the heart. , 2000, Cardiovascular research.

[170]  E. Huang,et al.  Human cytomegalovirus – no longer just a DNA virus , 2000, Nature Medicine.

[171]  P. Libby,et al.  Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction. , 2000, The Journal of clinical investigation.

[172]  P. Ping,et al.  Transgenic Overexpression of Constitutively Active Protein Kinase C ε Causes Concentric Cardiac Hypertrophy , 2000 .

[173]  G Baumgarten,et al.  Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[174]  R. Dietz,et al.  Differential regulation of cardiac ANP and BNP mRNA in different stages of experimental heart failure. , 2000, American journal of physiology. Heart and circulatory physiology.

[175]  P. Douglas,et al.  Transgenic expression of green fluorescence protein can cause dilated cardiomyopathy , 2000, Nature Medicine.

[176]  M. Redfield.  Epidemiology and pathophysiology of heart failure , 2000, Current cardiology reports.

[177]  K. Vranizan,et al.  Conditional expression of a Gi-coupled receptor causes ventricular conduction delay and a lethal cardiomyopathy. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[178]  G. Dorn,et al.  Early and delayed consequences of beta(2)-adrenergic receptor overexpression in mouse hearts: critical role for expression level. , 2000, Circulation.

[179]  S. Ooi,et al.  Cardiac And Vascular Responses In Deoxycorticosterone Acetate‐Salt Hypertensive Rats , 2000, Clinical and experimental pharmacology & physiology.

[180]  T. Hewett,et al.  Altered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1. , 2000, The Journal of clinical investigation.

[181]  N. Dali-Youcef,et al.  Overexpression of angiotensin II type I receptor in cardiomyocytes induces cardiac hypertrophy and remodeling. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[182]  A. Dart,et al.  Serial echocardiographic assessment of left ventricular dimensions and function after myocardial infarction in mice. , 2000, Cardiovascular research.

[183]  A. Dart,et al.  beta(2)-adrenergic receptor overexpression exacerbates development of heart failure after aortic stenosis. , 2000, Circulation.

[184]  E. Lakatta,et al.  Constitutive β2‐adrenergic signalling enhances sarcoplasmic reticulum Ca2+ cycling to augment contraction in mouse heart , 1999, The Journal of physiology.

[185]  C. Sweep,et al.  In Zucker Diabetic Fatty Rats Plasma Leptin Levels are Correlated with Plasma Insulin Levels rather than with Body Weight , 1999, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

[186]  M. Martone,et al.  Chronic Phospholamban–Sarcoplasmic Reticulum Calcium ATPase Interaction Is the Critical Calcium Cycling Defect in Dilated Cardiomyopathy , 1999, Cell.

[187]  E. Schiffrin,et al.  Blood pressure and small arteries in DOCA-salt-treated genetically AVP-deficient rats: role of endothelin. , 1999, Hypertension.

[188]  K. Campbell,et al.  Disruption of the Sarcoglycan–Sarcospan Complex in Vascular Smooth Muscle A Novel Mechanism for Cardiomyopathy and Muscular Dystrophy , 1999, Cell.

[189]  J Ross,et al.  Cardiac-specific overexpression of RhoA results in sinus and atrioventricular nodal dysfunction and contractile failure. , 1999, The Journal of clinical investigation.

[190]  D. Bernstein,et al.  Cardiovascular and Metabolic Alterations in Mice Lacking Both β1- and β2-Adrenergic Receptors* , 1999, The Journal of Biological Chemistry.

[191]  M. Lohse,et al.  Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[192]  K. Chien,et al.  Complexity in simplicity: monogenic disorders and complex cardiomyopathies. , 1999, The Journal of clinical investigation.

[193]  J. Ross,et al.  Loss of a gp130 Cardiac Muscle Cell Survival Pathway Is a Critical Event in the Onset of Heart Failure during Biomechanical Stress , 1999, Cell.

[194]  A. Sakamoto,et al.  Delineation of genomic deletion in cardiomyopathic hamster , 1999, FEBS letters.

[195]  D. Sawyer,et al.  Daunorubicin-induced apoptosis in rat cardiac myocytes is inhibited by dexrazoxane. , 1999, Circulation research.

[196]  M. Takaoka,et al.  Different contributions of endothelin-A and endothelin-B receptors in the pathogenesis of deoxycorticosterone acetate-salt-induced hypertension in rats. , 1999, Hypertension.

[197]  T. Doetschman,et al.  Impaired Cardiac Performance in Heterozygous Mice with a Null Mutation in the Sarco(endo)plasmic Reticulum Ca2+-ATPase Isoform 2 (SERCA2) Gene* , 1999, The Journal of Biological Chemistry.

[198]  E. Marbán,et al.  Targeted overexpression of the sarcoplasmic reticulum Ca2+-ATPase increases cardiac contractility in transgenic mouse hearts. , 1998, Circulation research.

[199]  E. Neer,et al.  Transient cardiac expression of constitutively active Galphaq leads to hypertrophy and dilated cardiomyopathy by calcineurin-dependent and independent pathways. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[200]  G. Dorn,et al.  Cardiac-specific Overexpression of Mouse Cardiac Calsequestrin Is Associated with Depressed Cardiovascular Function and Hypertrophy in Transgenic Mice* , 1998, The Journal of Biological Chemistry.

[201]  M. Prevost,et al.  A missense mutation in the αB-crystallin chaperone gene causes a desmin-related myopathy , 1998, Nature Genetics.

[202]  V. Ferrans,et al.  Preclinical animal models of cardiac protection from anthracycline-induced cardiotoxicity. , 1998, Seminars in oncology.

[203]  J. Ross,et al.  Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[204]  R. Lefkowitz,et al.  Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy. , 1998, Science.

[205]  Jeffrey Robbins,et al.  A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy , 1998, Cell.

[206]  M. Morad,et al.  Regulation of Ca2+ signaling in transgenic mouse cardiac myocytes overexpressing calsequestrin. , 1998, The Journal of clinical investigation.

[207]  D. Kass,et al.  In vivo murine left ventricular pressure-volume relations by miniaturized conductance micromanometry. , 1998, American journal of physiology. Heart and circulatory physiology.

[208]  P. Robitaille,et al.  31P-NMR analysis of congestive heart failure in the SHHF/Mcc-facp rat heart. , 1998, Journal of molecular and cellular cardiology.

[209]  Y. Murakami,et al.  Both hypertrophic and dilated cardiomyopathies are caused by mutation of the same gene, delta-sarcoglycan, in hamster: an animal model of disrupted dystrophin-associated glycoprotein complex. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[210]  T. Hewett,et al.  Cardiac compartment-specific overexpression of a modified retinoic acid receptor produces dilated cardiomyopathy and congestive heart failure in transgenic mice. , 1997, The Journal of clinical investigation.

[211]  A. Koretsky,et al.  Dilated Cardiomyopathy in Transgenic Mice With Cardiac-Specific Overexpression of Tumor Necrosis Factor-α , 1997 .

[212]  J. Sanes,et al.  Skeletal and Cardiac Myopathies in Mice Lacking Utrophin and Dystrophin: A Model for Duchenne Muscular Dystrophy , 1997, Cell.

[213]  M. Cho,et al.  Transgenic Mice with Cardiac Overexpression of α1B-Adrenergic Receptors , 1997, The Journal of Biological Chemistry.

[214]  G. King,et al.  Targeted overexpression of protein kinase C beta2 isoform in myocardium causes cardiomyopathy. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[215]  G. Dorn,et al.  Transgenic Gαq overexpression induces cardiac contractile failure in mice , 1997 .

[216]  H. Rockman,et al.  Overexpression of the rat sarcoplasmic reticulum Ca2+ ATPase gene in the heart of transgenic mice accelerates calcium transients and cardiac relaxation. , 1997, The Journal of clinical investigation.

[217]  S. Mccune,et al.  Plasma renin activity in heart failure-prone SHHF/Mcc-facp rats. , 1997, The American journal of physiology.

[218]  D. Sahn,et al.  Transballoon intravascular ultrasound imaging during balloon angioplasty in animal models with coarctation and branch pulmonary stenosis. , 1997, Circulation.

[219]  W. Lederer,et al.  Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure. , 1997, Science.

[220]  M. Pfeffer,et al.  The transition to failure in the spontaneously hypertensive rat. , 1997, American journal of hypertension.

[221]  E. Lakatta,et al.  Increased cardiomyocyte apoptosis during the transition to heart failure in the spontaneously hypertensive rat. , 1997, The American journal of physiology.

[222]  S. Pawlowski,et al.  Rescue of cardiac α-actin-deficient mice by enteric smooth muscle γ-actin , 1997 .

[223]  G. Yoshino,et al.  Effects of dietary fructose or glucose on triglyceride production and lipogenic enzyme activities in the liver of Wistar fatty rats, an animal model of NIDDM. , 1997, Endocrine journal.

[224]  Y. Hayashizaki,et al.  Identification of the Syrian hamster cardiomyopathy gene. , 1997, Human molecular genetics.

[225]  K. Shiota,et al.  Apoptosis in congestive heart failure induced by viral myocarditis in mice , 1997, Heart and Vessels.

[226]  R. Lefkowitz,et al.  Functional analysis of myocardial performance in murine hearts overexpressing the human beta 2-adrenergic receptor. , 1997, Journal of molecular and cellular cardiology.

[227]  Minoru Hongo,et al.  MLP-Deficient Mice Exhibit a Disruption of Cardiac Cytoarchitectural Organization, Dilated Cardiomyopathy, and Heart Failure , 1997, Cell.

[228]  O. Carretero,et al.  Chronic heart failure induced by coronary artery ligation in Lewis inbred rats. , 1997, The American journal of physiology.

[229]  Y. Capetanaki,et al.  Disruption of muscle architecture and myocardial degeneration in mice lacking desmin , 1996, The Journal of cell biology.

[230]  A. Dart,et al.  Response to cardiac sympathetic activation in transgenic mice overexpressing beta 2-adrenergic receptor. , 1996, The American journal of physiology.

[231]  S. Vatner,et al.  Adverse Effects of Chronic Endogenous Sympathetic Drive Induced by Cardiac Gsα Overexpression , 1996 .

[232]  L. Tartaglia,et al.  Phenotypes of Mouse diabetes and Rat fatty Due to Mutations in the OB (Leptin) Receptor , 1996, Science.

[233]  L. Tartaglia,et al.  Evidence That the Diabetes Gene Encodes the Leptin Receptor: Identification of a Mutation in the Leptin Receptor Gene in db/db Mice , 1996, Cell.

[234]  M. Böhm,et al.  Unchanged protein levels of SERCA II and phospholamban but reduced Ca2+ uptake and Ca(2+)-ATPase activity of cardiac sarcoplasmic reticulum from dilated cardiomyopathy patients compared with patients with nonfailing hearts. , 1995, Circulation.

[235]  M. Entman,et al.  Myocardial ischemia and reperfusion: a murine model. , 1995, The American journal of physiology.

[236]  A. Matsumori,et al.  Immunomodulating agents for the management of heart failure with myocarditis and cardiomyopathy--lessons from animal experiments. , 1995, European heart journal.

[237]  T. Mak,et al.  The role of transgenic knockout models in defining the pathogenesis of viral heart disease. , 1995, European heart journal.

[238]  R. Walsh,et al.  Differential changes in cardiac phospholamban and sarcoplasmic reticular Ca(2+)-ATPase protein levels. Effects on Ca2+ transport and mechanics in compensated pressure-overload hypertrophy and congestive heart failure. , 1995, Circulation research.

[239]  K. Chien,et al.  Ventricular Expression of a MLC-2v-ras Fusion Gene Induces Cardiac Hypertrophy and Selective Diastolic Dysfunction in Transgenic Mice (*) , 1995, The Journal of Biological Chemistry.

[240]  R. Lefkowitz,et al.  Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor. , 1995, Science.

[241]  T. Kishimoto,et al.  Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[242]  G. Aurigemma,et al.  Serial echocardiographic-Doppler assessment of left ventricular geometry and function in rats with pressure-overload hypertrophy. Chronic angiotensin-converting enzyme inhibition attenuates the transition to heart failure. , 1995, Circulation.

[243]  J. Rodin,et al.  Differential effects of fat and sucrose on the development of obesity and diabetes in C57BL/6J and A/J mice. , 1995, Metabolism: clinical and experimental.

[244]  T. Kenakin,et al.  Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the β2-adrenoceptor , 1995, Nature.

[245]  R. Lefkowitz,et al.  Marked enhancement in myocardial function resulting from overexpression of a human beta-adrenergic receptor gene. , 1995, The Journal of thoracic and cardiovascular surgery.

[246]  S Sasayama,et al.  Transition from compensatory hypertrophy to dilated, failing left ventricles in Dahl salt-sensitive rats. , 1994, The American journal of physiology.

[247]  E. R. Kloet,et al.  Central effects of mineralocorticoid antagonist RU-28318 on blood pressure of DOCA-salt hypertensive rats , 1994 .

[248]  R. Lefkowitz,et al.  Myocardial expression of a constitutively active alpha 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[249]  H. Schunkert,et al.  Angiotensin‐Converting Enzyme Inhibition Prolongs Survival and Modifies the Transition to Heart Failure in Rats With Pressure Overload Hypertrophy Due to Ascending Aortic Stenosis , 1994, Circulation.

[250]  T. Doetschman,et al.  Targeted ablation of the phospholamban gene is associated with markedly enhanced myocardial contractility and loss of beta-agonist stimulation. , 1994, Circulation research.

[251]  M. Pfeffer,et al.  Progressive ventricular remodeling in response to diffuse isoproterenol-induced myocardial necrosis in rats. , 1994, Circulation research.

[252]  C. H. Conrad,et al.  Alterations in cardiac gene expression during the transition from stable hypertrophy to heart failure. Marked upregulation of genes encoding extracellular matrix components. , 1994, Circulation research.

[253]  J. Ross,et al.  ANG II receptor blockade prevents ventricular hypertrophy and ANF gene expression with pressure overload in mice. , 1994, The American journal of physiology.

[254]  D K Burns,et al.  Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice. , 1994, The Journal of clinical investigation.

[255]  M. Fu,et al.  Properties of G-protein modulated receptor-adenylyl cyclase system in myocardium of spontaneously hypertensive rats treated with adriamycin. , 1994, International journal of cardiology.

[256]  M. Böhm,et al.  Expression of beta-arrestins and beta-adrenergic receptor kinases in the failing human heart. , 1994, Circulation research.

[257]  M. Zile,et al.  Native β‐Adrenergic Support for Left Ventricular Dysfunction in Experimental Mitral Regurgitation Normalizes Indexes of Pump and Contractile Function , 1994, Circulation.

[258]  R. Hruban,et al.  Myocarditis associated with doxorubicin cardiotoxicity. , 1993, American journal of clinical pathology.

[259]  A. Means,et al.  Targeted developmental overexpression of calmodulin induces proliferative and hypertrophic growth of cardiomyocytes in transgenic mice. , 1993, Endocrinology.

[260]  B. Lorell,et al.  Selective changes in cardiac gene expression during compensated hypertrophy and the transition to cardiac decompensation in rats with chronic aortic banding. , 1993, Circulation research.

[261]  H. Noguchi,et al.  The High Incidence of Atrial Thrombosis in Mice Given Doxorubicin , 1993, Toxicologic pathology.

[262]  R. Olson,et al.  Doxorubicin cardiomyopathy is associated with a decrease in calcium release channel of the sarcoplasmic reticulum in a chronic rabbit model. , 1993, The Journal of clinical investigation.

[263]  K. Kawano,et al.  Spontaneous Long-Term Hyperglycemic Rat With Diabetic Complications: Otsuka Long-Evans Tokushima Fatty (OLETF) Strain , 1992, Diabetes.

[264]  S. Gardiner,et al.  Functional consequences of streptozotocin-induced diabetes mellitus, with particular reference to the cardiovascular system. , 1992, Pharmacological reviews.

[265]  J. Ross,et al.  Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[266]  A. Gerdes,et al.  Regional changes in hemodynamics and cardiac myocyte size in rats with aortocaval fistulas. 1. Developing and established hypertrophy. , 1991, Circulation research.

[267]  J. Rouleau,et al.  Adriamycin-induced changes to the myocardial beta-adrenergic system in the rabbit. , 1991, Journal of molecular and cellular cardiology.

[268]  H. Schunkert,et al.  Increased rat cardiac angiotensin converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy. Effects on coronary resistance, contractility, and relaxation. , 1990, The Journal of clinical investigation.

[269]  R. Garcia,et al.  Simple, rapid, and effective method of producing aortocaval shunts in the rat. , 1990, Cardiovascular research.

[270]  M. Böhm,et al.  Evidence against spare or uncoupled β-adrenoceptors in the human heart* , 1990 .

[271]  A. Gerdes,et al.  Right ventricular performance after monocrotaline-induced pulmonary hypertension. , 1989, The American journal of physiology.

[272]  C. Liew,et al.  Construction of cosmid genomic libraries for the normal and myopathic Syrian hamsters. , 1987, Biochemistry and cell biology = Biochimie et biologie cellulaire.

[273]  M. Fregly,et al.  Mineralocorticoids modulate central angiotensin II receptors in rats , 1986, Brain Research.

[274]  C. Johnston,et al.  Adriamycin cardiomyopathy in the rabbit: an animal model of low output cardiac failure with activation of vasoconstrictor mechanisms. , 1985, Cardiovascular research.

[275]  E. G. Hunter,et al.  Cardiomyopathic hamsters, CHF 146 and CHF 147: a preliminary study. , 1984, Canadian journal of physiology and pharmacology.

[276]  C. Porter,et al.  Differential effects of diltiazem and nitroprusside on left ventricular function in experimental chronic volume overload. , 1983, Circulation.

[277]  A. Matsumori,et al.  An Experimental Model for Congestive Heart Failure After Encephalomyocarditis Virus Myocarditis in Mice , 1982, Circulation.

[278]  M. Pfeffer,et al.  Regression of left ventricular hypertrophy and prevention of left ventricular dysfunction by captopril in the spontaneously hypertensive rat. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[279]  E. Frohlich,et al.  Regression of Left Ventricular Hypertrophy in Two‐Kidney, One Clip Goldblatt Hypertension , 1982, Hypertension.

[280]  S. Oparil,et al.  Importance of Renal Sympathetic Tone in the Development of DOCA‐Salt Hypertension in the Rat , 1980, Hypertension.

[281]  M. Pfeffer,et al.  Cardiac function and morphology with aging in the spontaneously hypertensive rat. , 1979, The American journal of physiology.

[282]  F. Leenen,et al.  Plasma renin activity and sodium, potassium and water excretion during reversal of hypertension in the one-clip two-kidney hypertensive rat. , 1979, Clinical science.

[283]  M. Pfeffer,et al.  Myocardial Infarct Size and Ventricular Function in Rats , 1979, Circulation research.

[284]  G. Jasmin,et al.  CARDIOMYOPATHY OF HAMSTER DYSTROPHY * , 1979, Annals of the New York Academy of Sciences.

[285]  F. Homburger.  MYOPATHY OF HAMSTER DYSTROPHY: HISTORY AND MORPHOLOGIC ASPECTS , 1979, Annals of the New York Academy of Sciences.

[286]  Randolph P. Martin,et al.  Early anthracycline cardiotoxicity. , 1978, The American journal of medicine.

[287]  F. Leenen,et al.  Plasma Renin and Sodium Balance During Development of Moderate and Severe Renal Hypertension in Rats , 1975, Circulation research.

[288]  J. Pitha,et al.  A clinicopathologic analysis of adriamycin cardiotoxicity , 1973, Cancer.

[289]  H. B. Stoner,et al.  Pulmonary oedema in rats given monocrotaline pyrrole , 1972, The Journal of pathology.

[290]  C. Rerup.  Drugs producing diabetes through damage of the insulin secreting cells. , 1970, Pharmacological reviews.

[291]  D. Heath,et al.  Electron microscopy of Crotalaria pulmonary hypertension , 1969, Thorax.

[292]  G. Zbinden,et al.  PHARMACOLOGICAL STUDIES ON HEART MUSCLE LESIONS INDUCED BY ISOPROTERENOL , 1969, Annals of the New York Academy of Sciences.

[293]  J. R. Baker,et al.  HEREDITARY MYOPATHY IN THE SYRIAN HAMSTER: STUDIES ON PATHOGENESIS * , 1966, Annals of the New York Academy of Sciences.

[294]  V. Ferrans,et al.  Electron microscopic observations on lysosomes and related cytoplasmic components of normal and pathological cardiac muscle , 1965, The Anatomical record.

[295]  G. Zbinden,et al.  ISOPROTERENOL-INDUCED HEART NECROSIS, AN EXPERIMENTAL MODEL FOR THE STUDY OF ANGINA PECTORIS AND MYOCARDIAL INFARCT. , 1963, Revue canadienne de biologie.

[296]  N. Rakieten,et al.  Studies on the diabetogenic action of streptozotocin (NSC-37917). , 1963, Cancer chemotherapy reports.

[297]  J. Baker,et al.  New hereditary disease of Syrian hamsters. Primary, generalized polymyopathy and cardiac necrosis. , 1962, Archives of internal medicine.

[298]  LEWIS K. DAHL,et al.  Role of Genetic Factors in Susceptibility to Experimental Hypertension due to Chronic Excess Salt Ingestion , 1962, Nature.

[299]  M. A. Head,et al.  Pathological Changes in Rats as a Result of Treatment with Monocrotaline , 1955, British Journal of Cancer.

[300]  M. Dickie,et al.  Obese, a new mutation in the house mouse. , 1950, Obesity research.

[301]  H. Selye.  Production of Nephrosclerosis by Overdosage with Desoxycorticosterone Acetate. , 1942, Canadian Medical Association journal.

[302]  H. Goldblatt,et al.  STUDIES ON EXPERIMENTAL HYPERTENSION , 1934, The Journal of experimental medicine.

[303]  A. Feldman,et al.  Matrix Metalloproteinases in the Progression of Heart Failure , 2012, Drugs.

[304]  Y. Zou,et al.  The therapeutic potential of G-CSF in pressure overload induced ventricular reconstruction and heart failure in mice , 2011, Molecular Biology Reports.

[305]  M. Movsesian,et al.  Phosphodiesterase inhibition in heart failure. , 2011, Handbook of experimental pharmacology.

[306]  D. Mozaffarian,et al.  Executive summary: heart disease and stroke statistics--2010 update: a report from the American Heart Association. , 2010, Circulation.

[307]  D. Lefer,et al.  Myocardial infarction and heart failure in the db/db diabetic mouse. , 2006, American journal of physiology. Heart and circulatory physiology.

[308]  H. Witt,et al.  Microarray analysis to evaluate different animal models for human heart failure. , 2006, Journal of molecular and cellular cardiology.

[309]  S. Neubauer,et al.  Serial high resolution 3D–MRI after aortic banding in mice: band internalization is a source of variability in the hypertrophic response , 2005, Basic Research in Cardiology.

[310]  Seung‐Woo Cho,et al.  Implantation of bone marrow mononuclear cells using injectable fibrin matrix enhances neovascularization in infarcted myocardium. , 2005, Biomaterials.

[311]  Luigi Fratta,et al.  Melusin, a muscle-specific integrin β1–interacting protein, is required to prevent cardiac failure in response to chronic pressure overload , 2003, Nature Medicine.

[312]  E. Creemers,et al.  Deficiency of TIMP-1 exacerbates LV remodeling after myocardial infarction in mice. , 2003, American journal of physiology. Heart and circulatory physiology.

[313]  Xianlin Han,et al.  The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus. , 2002, The Journal of clinical investigation.

[314]  F. Müller,et al.  Junctional sarcoplasmic reticulum transmembrane proteins in the heart , 2002, Basic Research in Cardiology.

[315]  W. Koch,et al.  Genetic Alterations That Inhibit In Vivo Pressure-Overload Hypertrophy Prevent Cardiac Dysfunction Despite Increased Wall Stress , 2002, Circulation.

[316]  E. Schiffrin.  Endothelin: role in experimental hypertension. , 2000, Journal of cardiovascular pharmacology.

[317]  M. Hori,et al.  Development of different phenotypes of hypertensive heart failure: systolic versus diastolic failure in Dahl salt‐sensitive rats , 2000, Journal of hypertension.

[318]  Chekanov Vs.  A stable model of chronic bilateral ventricular insufficiency (dilated cardiomyopathy) induced by arteriovenous anastomosis and doxorubicin administration in sheep. , 1999 .

[319]  H. Schunkert,et al.  Development of heart failure following isoproterenol administration in the rat: role of the renin-angiotensin system. , 1998, Cardiovascular research.

[320]  W. Lineaweaver,et al.  A new heart failure model in rat by an end-to-side femoral vessel anastomosis. , 1998, Cardiovascular research.

[321]  S. Takahashi,et al.  Effects of in vitro and in vivo exposure to doxorubicin (adriamycin) on caffeine-induced Ca2+ release from sarcoplasmic reticulum and contractile protein function in 'chemically-skinned' rabbit ventricular trabeculae. , 1998, Japanese journal of pharmacology.

[322]  M. Kodama,et al.  Expression of inducible nitric oxide synthase in rat experimental autoimmune myocarditis with special reference to changes in cardiac hemodynamics. , 1997, Circulation research.

[323]  C. H. Conrad,et al.  The spontaneously hypertensive rat as a model of the transition from compensated left ventricular hypertrophy to failure. , 1995, Journal of molecular and cellular cardiology.

[324]  H. Ito,et al.  Decreased superoxide dismutase activity and increased superoxide anion production in cardiac hypertrophy of spontaneously hypertensive rats. , 1995, Clinical and experimental hypertension.

[325]  Y. Yamori.  Overview: studies on spontaneous hypertension-development from animal models toward man. , 1991, Clinical and experimental hypertension. Part A, Theory and practice.

[326]  M. Nagano,et al.  Protective effect of ACE- and kininase-inhibitor on the onset of cardiomyopathy. , 1991, Basic research in cardiology.

[327]  J. Cohn.  The Sympathetic Nervous System in Heart Failure , 1989, Journal of cardiovascular pharmacology.

[328]  M. Sasaki,et al.  Development of diabetes in the non-obese NIDDM rat (GK rat). , 1988, Advances in experimental medicine and biology.

[329]  B. E. Watkins,et al.  Effects of continuous converting enzyme blockade on renovascular hypertension in the rat. , 1979, The American journal of physiology.

[330]  N. Rakieten.  Studies on the diabetogenic action of streptozotocin , 1963 .