Expression of active recombinant human alpha 1-antitrypsin in transgenic rabbits.
暂无分享,去创建一个
R. Bischoff | D. Clesse | L. Houdebine | A. Pavirani | H. Pointu | W. Dalemans | J. Attal | M. Stinnakre | M. Massoud | H. Schultz | Andrea Pavirani | Wilfried Dalemans | Rainer Bischoff | Louis M. Houdebine
[1] A. Balland,et al. Characterization of recombinant human factor IX expressed in transgenic mice and in derived trans‐immortalized hepatic cell lines. , 1990, The EMBO journal.
[2] M. Perricaudet,et al. Expression of human α1‐antitrypsin using a recombinant adenovirus vector , 1990 .
[3] A. Archibald,et al. High-level expression of biologically active human alpha 1-antitrypsin in the milk of transgenic mice. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[4] K. Bürki,et al. Rabbit β-Casein Promoter Directs Secretion of Human Interleukin-2 into the Milk of Transgenic Rabbits , 1990, Bio/Technology.
[5] L. Houdebine,et al. An improvement of the single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. , 1990, BioTechniques.
[6] A. Sepulveda,et al. Development of a transgenic mouse system for the analysis of stages in liver carcinogenesis using tissue-specific expression of SV40 large T-antigen controlled by regulatory elements of the human alpha-1-antitrypsin gene. , 1989, Cancer research.
[7] R. Lathe,et al. Recombinant Proteins of Therapeutic Interest Expressed by Lymphoid Cell Lines Derived from Transgenic Mice , 1989, Nature Biotechnology.
[8] R. Crystal,et al. Recombinant DNA-produced alpha 1-antitrypsin administered by aerosol augments lower respiratory tract antineutrophil elastase defenses in individuals with alpha 1-antitrypsin deficiency. , 1989, The Journal of clinical investigation.
[9] M. Mahmoudi,et al. Comparison of two different hybridization systems in northern transfer analysis. , 1989, BioTechniques.
[10] R. Shen,et al. Tissue-Specific Regulation of Human α1-Antitrypsin Gene Expression in Transgenic Mice , 1989 .
[11] S. Hauser,et al. A simple method for DNA purification from peripheral blood. , 1988, Analytical biochemistry.
[12] J. Carlson,et al. Multiple tissues express alpha 1-antitrypsin in transgenic mice and man. , 1988, The Journal of clinical investigation.
[13] V. Oi,et al. Transgenic rabbits with lymphocytic leukemia induced by the c-myc oncogene fused with the immunoglobulin heavy chain enhancer. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[14] R. Lathe,et al. Gene Transfer into Sheep , 1988, Bio/Technology.
[15] M. Casolaro,et al. Augmentation of lung antineutrophil elastase capacity with recombinant human alpha-1-antitrypsin. , 1987, Journal of applied physiology.
[16] E. Wagner,et al. The human alpha-1-antitrypsin gene is efficiently expressed from two tissue-specific promotors in transgenic mice. , 1987, Nucleic acids research.
[17] R. Crystal,et al. Replacement therapy for alpha 1-antitrypsin deficiency associated with emphysema. , 1987, The New England journal of medicine.
[18] R. Lovell-Badge,et al. Species- and tissue-specific expression of human alpha 1-antitrypsin in transgenic mice. , 1987, Genes & development.
[19] F. DeMayo,et al. Tissue specific expression of the human alpha-1-antitrypsin gene in transgenic mice. , 1987, Nucleic acids research.
[20] R. Palmiter,et al. Genetic engineering of mammalian embryos. , 1986, Journal of animal science.
[21] R. Crystal,et al. Synthesis in E. coli of α1-antitrypsin variants of therapeutic potential for emphysema and thrombosis , 1985, Nature.
[22] R. Lathe,et al. High-level production of biologically active human alpha 1-antitrypsin in Escherichia coli. , 1984, Proceedings of the National Academy of Sciences of the United States of America.
[23] R. Carrell,et al. Structure and variation of human α1–antitrypsin , 1982, Nature.
[24] R. Crystal. The α1-antitrypsin gene and its deficiency states , 1989 .
[25] R. Lovell-Badge,et al. Widespread expression of human alpha 1-antitrypsin in transgenic mice revealed by in situ hybridization. , 1989, Genes & development.
[26] R. Crystal,et al. Fate of aerosolized recombinant DNA-produced alpha 1-antitrypsin: use of the epithelial surface of the lower respiratory tract to administer proteins of therapeutic importance. , 1989, Proceedings of the National Academy of Sciences of the United States of America.