Union-intersection principle and constrained statistical inference

Abstract Most statistical models arising in real life applications as well as in interdisciplinary research are complex in their designs, sampling plans, and associated probability laws, which in turn are often constrained by inequality, order, functional, shape or other restraints. Optimality of conventional likelihood ratio based statistical inference may not be tenable here, although the use of restricted or quasi-likelihood has spurred in such environments. S.N. Roy's ingenious union–intersection principle provides an alternative avenue, often having some computational advantages, increased scope of adaptability, and flexibility beyond conventional likelihood paradigms. This scenario is appraised here with some illustrative examples, and with some interesting problems of inference on stochastic ordering (dominance) in parametric as well as beyond parametric setups.

[1]  P. Sen,et al.  High-Dimension, Low–Sample Size Perspectives in Constrained Statistical Inference , 2007 .

[2]  Ajaya K. Gupta Advances in Multivariate Statistical Analysis , 1987 .

[3]  J. Roy,et al.  STEP-DOWN PROCEDURE IN MULTIVARIATE ANALYSIS , 1958 .

[4]  G. S. Mudholkar,et al.  Robust finite-intersection tests for homogeneity of ordered variances , 1995 .

[5]  A. Forcina,et al.  A Unified Approach to Likelihood Inference on Stochastic Orderings in a Nonparametric Context , 1998 .

[6]  K. K. Lan,et al.  Discrete sequential boundaries for clinical trials , 1983 .

[7]  Govind S. Mudholkar,et al.  A Simple Approach to Testing Homogeneity of Order-Constrained Means , 1993 .

[8]  J. N. Srivastava,et al.  Analysis and design of certain quantitative multiresponse experiments , 1971 .

[9]  R. Simes,et al.  An improved Bonferroni procedure for multiple tests of significance , 1986 .

[10]  Govind S. Mudholkar,et al.  A class of tests for equality of ordered means , 1989 .

[11]  P. Sen Some remarks on Simes-type multiple tests of significance , 1999 .

[12]  Y. Benjamini,et al.  Controlling the false discovery rate: a practical and powerful approach to multiple testing , 1995 .

[13]  R. Wijsman,et al.  Constructing All Smallest Simultaneous Confidence Sets in a Given Class with Applications to MANOVA , 1979 .

[14]  Pranab Kumar Sen,et al.  Nonparametric Testing Under Progressive Censoring* , 1973 .

[15]  S. N. Roy On a Heuristic Method of Test Construction and its use in Multivariate Analysis , 1953 .

[16]  P. Sen A fisherian detour of the step-down procedure , 1981 .

[17]  S. Kullback,et al.  Some Aspects of Multivariate Analysis. , 1958 .

[18]  P. Sen,et al.  Restricted canonical correlations , 1994 .

[19]  Paramsothy Silvapulle,et al.  A Score Test against One-Sided Alternatives , 1995 .

[20]  M. Tsai Maximum likelihood estimation of covariance matrices under simple tree ordering , 2004 .

[21]  David R. Cox,et al.  Regression models and life tables (with discussion , 1972 .

[22]  Sanat K. Sarkar,et al.  FDR-CONTROLLING STEPWISE PROCEDURES AND THEIR FALSE NEGATIVES RATES , 2004 .

[23]  S S Ellenberg,et al.  Placebo-Controlled Trials and Active-Control Trials in the Evaluation of New Treatments. Part 1: Ethical and Scientific Issues , 2000, Annals of Internal Medicine.

[24]  A note on the monotonicity of the critical values of a step-up test , 2000 .

[25]  P. Sen,et al.  Asymptotically optimal tests for parametric functions against ordered functional alternatives , 2005 .

[26]  P. Sen NONPARAMETRIC TESTS FOR ORDERED DIVERSITY IN A GENOMIC SEQUENCE , 2005 .

[27]  Pranab Kumar Sen,et al.  On the Theory of Rank Order Tests for Location in the Multivariate One Sample Problem , 1967 .

[28]  G. S. Mudholkar,et al.  Testing significance of a mean vector—A possible alternative to Hotelling'sT2 , 1980 .

[29]  F. T. Wright,et al.  Order restricted statistical inference , 1988 .

[30]  Alexander Shapiro,et al.  On the asymptotics of constrained local M-estimators , 2000 .

[31]  Y. Hochberg A sharper Bonferroni procedure for multiple tests of significance , 1988 .

[32]  S. Sarkar Some probability inequalities for ordered $\rm MTP\sb 2$ random variables: a proof of the Simes conjecture , 1998 .

[33]  A. Wald Tests of statistical hypotheses concerning several parameters when the number of observations is large , 1943 .

[34]  P. Sen SURVIVAL ANALYSIS: PARAMETRICS TO SEMIPARAMETRICS TO PHARMACOGENOMICS , 2001 .

[35]  Samuel Karlin,et al.  A First Course on Stochastic Processes , 1968 .

[36]  Pranab Kumar Sen,et al.  Sequential Nonparametrics: Invariance Principles and Statistical Inference , 1981 .

[37]  Michael D. Perlman,et al.  One-Sided Testing Problems in Multivariate Analysis , 1969 .

[38]  S. Sarkar,et al.  The Simes Method for Multiple Hypothesis Testing with Positively Dependent Test Statistics , 1997 .

[39]  P. Sen Multiple comparisons in interim analysis , 1999 .

[40]  P. Sen,et al.  Constrained Statistical Inference: Inequality, Order, and Shape Restrictions , 2001 .

[41]  David M. De Long Crossing probabilities for a square root boundary by a bessel process , 1981 .

[42]  G. S. Mudholkar,et al.  ROBUST TESTS FOR THE SIGNIFICANCE OF ORTHANT RESTRICTED MEAN VECTOR , 2001 .

[43]  S. Sarkar Some Results on False Discovery Rate in Stepwise multiple testing procedures , 2002 .

[44]  A. W. Kemp,et al.  Contributions to Statistics: Essays in Honour of Norman Lloyd Johnson. , 1984 .

[45]  J. Kalbfleisch Statistical Inference Under Order Restrictions , 1975 .

[46]  Mervyn J. Silvapulle,et al.  A Hotelling's T 2 -type statistic for testing against one-sided hypotheses , 1995 .

[47]  Pranab Kumar Sen,et al.  Two-Stage Likelihood Ratio and Union-Intersection Tests for One-Sided Alternatives Multivariate Mean with Nuisance Dispersion Matrix , 1999 .