Siponimod vs placebo in active secondary progressive multiple sclerosis: a post hoc analysis from the phase 3 EXPAND study
暂无分享,去创建一个
D. Arnold | L. Kappos | P. Vermersch | A. Bar-Or | R. Gold | F. Dahlke | G. Giovannoni | R. Fox | I. Penner | B. Cree | R. Benedict | N. Rouyrre | T. Hach | S. Ritter | D. Piani-Meier | Ajay Kilaru | Göril Karlsson
[1] R. Gold,et al. 114 Effect of siponimod on cognitive processing speed in SPMS patients with active and non-active disease , 2022, Journal of Neurology, Neurosurgery, and Psychiatry.
[2] D. Arnold,et al. Long-term efficacy and safety of siponimod in patients with secondary progressive multiple sclerosis: Analysis of EXPAND core and extension data up to >5 years , 2022, Multiple sclerosis.
[3] D. Arnold,et al. Effect of siponimod on magnetic resonance imaging measures of neurodegeneration and myelination in secondary progressive multiple sclerosis: Gray matter atrophy and magnetization transfer ratio analyses from the EXPAND phase 3 trial , 2022, Multiple sclerosis.
[4] E. Briard,et al. Siponimod (BAF312) penetrates, distributes, and acts in the central nervous system: Preclinical insights , 2021, Multiple sclerosis journal - experimental, translational and clinical.
[5] Thomas E. Nichols,et al. Characterisation of MS phenotypes across the age span using a novel data set integrating 34 clinical trials (NO.MS cohort): Age is a key contributor to presentation , 2021, Multiple sclerosis.
[6] L. Kappos,et al. Siponimod and Cognition in Secondary Progressive Multiple Sclerosis , 2020, Neurology.
[7] Baldur P Magnusson,et al. Siponimod: Disentangling disability and relapses in secondary progressive multiple sclerosis , 2020, Multiple sclerosis.
[8] J. DeLuca,et al. Cognitive impairment in multiple sclerosis: clinical management, MRI, and therapeutic avenues , 2020, The Lancet Neurology.
[9] R. Viterbo,et al. Associations between cognitive impairment at onset and disability accrual in young people with multiple sclerosis , 2019, Scientific Reports.
[10] B. Demeneix,et al. The Xenopus tadpole: An in vivo model to screen drugs favoring remyelination , 2018, Multiple sclerosis.
[11] Ludwig Kappos,et al. Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study , 2018, The Lancet.
[12] C. Oreja-Guevara,et al. Functional Components of Cognitive Impairment in Multiple Sclerosis: A Cross-Sectional Investigation , 2017, Front. Neurol..
[13] M. Trojano,et al. Age and disability drive cognitive impairment in multiple sclerosis across disease subtypes , 2017, Multiple sclerosis.
[14] M. Calabrese,et al. Cognitive impairment predicts disability progression and cortical thinning in MS: An 8-year study , 2017, Multiple sclerosis.
[15] H. Genova,et al. Information processing speed in multiple sclerosis: Past, present, and future , 2017, Multiple sclerosis.
[16] Lynn D. Hudson,et al. Validity of the Symbol Digit Modalities Test as a cognition performance outcome measure for multiple sclerosis , 2017, Multiple sclerosis.
[17] D. Centonze,et al. Siponimod (BAF312) prevents synaptic neurodegeneration in experimental multiple sclerosis , 2016, Journal of Neuroinflammation.
[18] F. Zipp,et al. Secondary Progression in Multiple Sclerosis: Neuronal Exhaustion or Distinct Pathology? , 2016, Trends in Neurosciences.
[19] K. Dev,et al. The dual S1PR1/S1PR5 drug BAF312 (Siponimod) attenuates demyelination in organotypic slice cultures , 2016, Journal of Neuroinflammation.
[20] V. Planche,et al. Cognitive impairment in a population‐based study of patients with multiple sclerosis: differences between late relapsing−remitting, secondary progressive and primary progressive multiple sclerosis , 2016, European journal of neurology.
[21] A. Glabinski,et al. Neural Plasticity in Multiple Sclerosis: The Functional and Molecular Background , 2015, Neural plasticity.
[22] F. Jacques. Defining the clinical course of multiple sclerosis: The 2013 revisions , 2015, Neurology.
[23] N. Gray,et al. The selective sphingosine 1-phosphate receptor modulator BAF312 redirects lymphocyte distribution and has species-specific effects on heart rate , 2012, British journal of pharmacology.
[24] M. Rovaris,et al. Secondary progressive multiple sclerosis: current knowledge and future challenges , 2006, The Lancet Neurology.
[25] J. Baskerville,et al. The natural history of multiple sclerosis: a geographically based study 9: observations on the progressive phase of the disease. , 2006, Brain : a journal of neurology.
[26] Hans Lassmann,et al. Cortical demyelination and diffuse white matter injury in multiple sclerosis. , 2005, Brain : a journal of neurology.
[27] M. Pangalos,et al. Edg8/S1P5: An Oligodendroglial Receptor with Dual Function on Process Retraction and Cell Survival , 2005, The Journal of Neuroscience.
[28] D. Holdstock. Past, present--and future? , 2005, Medicine, conflict, and survival.
[29] R. Proia,et al. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1 , 2004, Nature.
[30] T. Fog,et al. [Multiple sclerosis; review]. , 1954, Maanedsskrift for praktisk laegegerning og social Medicin.