Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions.
暂无分享,去创建一个
[1] Yan Xu,et al. Formation of the G-quadruplex and i-motif structures in retinoblastoma susceptibility genes (Rb) , 2006, Nucleic acids research.
[2] Shankar Balasubramanian,et al. G-quadruplexes in promoters throughout the human genome , 2006, Nucleic acids research.
[3] T. Littlewood,et al. Action of Myc in vivo - proliferation and apoptosis. , 2000, Current opinion in genetics & development.
[4] S. Maiti,et al. Thermodynamics of i-tetraplex formation in the nuclease hypersensitive element of human c-myc promoter. , 2004, Biochemical and biophysical research communications.
[5] J. Feigon,et al. Three-dimensional solution structure of the thrombin-binding DNA aptamer d(GGTTGGTGTGGTTGG). , 1994, Journal of molecular biology.
[6] S. Balasubramanian,et al. Single-molecule conformational analysis of G-quadruplex formation in the promoter DNA duplex of the proto-oncogene c-kit. , 2007, Journal of the American Chemical Society.
[7] Michael Fry,et al. Tetraplex DNA and its interacting proteins. , 2007, Frontiers in bioscience : a journal and virtual library.
[8] N. Maizels,et al. Gene function correlates with potential for G4 DNA formation in the human genome , 2006, Nucleic acids research.
[9] W. Doerfler,et al. A 5′-CG-3′-rich region in the promoter of the transcriptionally frequently silenced RET protooncogene lacks methylated cytidine residues , 1998, Oncogene.
[10] Sarah W. Burge,et al. Quadruplex DNA: sequence, topology and structure , 2006, Nucleic acids research.
[11] M. Shibuya,et al. Characterization of the Promoter Region of the Human c‐kit Proto‐oncogene , 1993, Japanese journal of cancer research : Gann.
[12] H. Kim,et al. Platelet-derived growth factor signaling and human cancer. , 2003, Journal of biochemistry and molecular biology.
[13] N. Maizels,et al. Conserved elements with potential to form polymorphic G-quadruplex structures in the first intron of human genes , 2008, Nucleic acids research.
[14] L. Hurley,et al. Deconvoluting the structural and drug-recognition complexity of the G-quadruplex-forming region upstream of the bcl-2 P1 promoter. , 2006, Journal of the American Chemical Society.
[15] L. Hurley,et al. The dynamic character of the G-quadruplex element in the c-MYC promoter and modification by TMPyP4. , 2004, Journal of the American Chemical Society.
[16] M. Henriksson,et al. c-myc Suppression in Burkitt's lymphoma cells. , 2002, Biochemical and biophysical research communications.
[17] N. Jing,et al. Structure-Activity of Tetrad-forming Oligonucleotides as a Potent Anti-HIV Therapeutic Drug* , 1998, The Journal of Biological Chemistry.
[18] S. Cogoi,et al. G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription , 2006, Nucleic acids research.
[19] R. Quatrano. Genomics , 1998, Plant Cell.
[20] M. Lieber,et al. DNA structure and human diseases. , 2007, Frontiers in bioscience : a journal and virtual library.
[21] S. Neidle,et al. Highly prevalent putative quadruplex sequence motifs in human DNA , 2005, Nucleic acids research.
[22] L. Hurley,et al. Characterization of the G-quadruplexes in the duplex nuclease hypersensitive element of the PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4 , 2007, Nucleic acids research.
[23] I Berger,et al. In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[24] M. Groudine,et al. Control of c-myc regulation in normal and neoplastic cells. , 1991, Advances in cancer research.
[25] A. Firulli,et al. DNA triplexes and regulation of the c-myc gene. , 1994, Gene.
[26] Z. Wang,et al. Promoter region of the human platelet-derived growth factor A-chain gene. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[27] Jean-Louis Mergny,et al. Quartets in G‐major , 2007, EMBO reports.
[28] D. Levens,et al. The functional response of upstream DNA to dynamic supercoiling in vivo , 2008, Nature Structural &Molecular Biology.
[29] P. Leder,et al. Chromatin structure and protein binding in the putative regulatory region of the c-myc gene in burkitt lymphoma , 1984, Cell.
[30] M. Cole,et al. The Myc oncoprotein: a critical evaluation of transactivation and target gene regulation , 1999, Oncogene.
[31] A. Tulinsky,et al. The structure of alpha-thrombin inhibited by a 15-mer single-stranded DNA aptamer. , 1994, The Journal of biological chemistry.
[32] Haiyong Han,et al. The cationic porphyrin TMPyP4 down-regulates c-MYC and human telomerase reverse transcriptase expression and inhibits tumor growth in vivo. , 2002, Molecular cancer therapeutics.
[33] J. Ostrowski,et al. Diverse molecular interactions of the hnRNP K protein , 1997, FEBS letters.
[34] Laurence H. Hurley,et al. Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents , 2005, Nucleic acids research.
[35] J. Feigon,et al. Thrombin-binding DNA aptamer forms a unimolecular quadruplex structure in solution. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[36] J. Hayman,et al. Myb expression is higher in malignant human colonic carcinoma and premalignant adenomatous polyps than in normal mucosa. , 1992, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[37] Roger A. Jones,et al. Solution structure of the biologically relevant G-quadruplex element in the human c-MYC promoter. Implications for G-quadruplex stabilization. , 2005, Biochemistry.
[38] Danzhou Yang,et al. Structure of the Biologically Relevant G-Quadruplex in The c-MYC Promoter , 2006, Nucleosides, nucleotides & nucleic acids.
[39] D. Bearss,et al. Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[40] C. C. Hardin,et al. Telomeric DNA oligonucleotides form novel intramolecular structures containing guanine·guanine base pairs , 1987, Cell.
[41] Sarah W. Burge,et al. Structure of an unprecedented G-quadruplex scaffold in the human c-kit promoter. , 2007, Journal of the American Chemical Society.
[42] Dipankar Sen,et al. A sodium-potassium switch in the formation of four-stranded G4-DNA , 1990, Nature.
[43] L. Mulligan,et al. Sp1 and Sp3 transactivate the RET proto-oncogene promoter. , 2000, Gene.
[44] Max A. Keniry,et al. Quadruplex structures in nucleic acids , 2000, Biopolymers.
[45] Yan Xu,et al. Highly efficient photochemical 2'-deoxyribonolactone formation at the diagonal loop of a 5-iodouracil-containing antiparallel G-quartet. , 2004, Journal of the American Chemical Society.
[46] B. Meunier,et al. Oxidative damage generated by an oxo-metalloporphyrin onto the human telomeric sequence. , 2000, Biochemistry.
[47] E. Reddy,et al. The myb gene family in cell growth, differentiation and apoptosis , 1999, Oncogene.
[48] Binding of single-stranded oligonucleotides to a non-B-form DNA structure results in loss of promoter activity of the platelet-derived growth factor A-chain gene. , 1992, The Journal of biological chemistry.
[49] G. Semenza,et al. Structural and functional analysis of hypoxia-inducible factor 1. , 1997, Kidney international.
[50] Keith R Fox,et al. Influence of loop size on the stability of intramolecular DNA quadruplexes. , 2004, Nucleic acids research.
[51] P. V. von Hippel,et al. The role of DNA structure in genetic regulation. , 1977, CRC critical reviews in biochemistry.
[52] J. Feigon,et al. The selectivity for K+ versus Na+ in DNA quadruplexes is dominated by relative free energies of hydration: a thermodynamic analysis by 1H NMR. , 1996, Biochemistry.
[53] Shankar Balasubramanian,et al. Prevalence of quadruplexes in the human genome , 2005, Nucleic acids research.
[54] Roger A. Jones,et al. NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region , 2006, Nucleic acids research.
[55] H. Krutzsch,et al. Cellular Nucleic Acid Binding Protein Regulates the CT Element of the Human c- myc Protooncogene (*) , 1995, The Journal of Biological Chemistry.
[56] R. Wells,et al. Unusual DNA Structures , 2011, Springer New York.
[57] D. Patel,et al. Identifying hydrogen bond alignments in multistranded DNA architectures by NMR. , 2002, Accounts of chemical research.
[58] M. Hogan,et al. DNA structure equilibria in the human c-myc gene. , 1987, Biochemistry.
[59] J. Abbruzzese,et al. Constitutive Sp1 activity is essential for differential constitutive expression of vascular endothelial growth factor in human pancreatic adenocarcinoma. , 2001, Cancer research.
[60] L. Hurley,et al. The proximal promoter region of the human vascular endothelial growth factor gene has a G-quadruplex structure that can be targeted by G-quadruplex–interactive agents , 2008, Molecular Cancer Therapeutics.
[61] R. Larson,et al. Studies of the human c-myb gene and its product in human acute leukemias. , 1986, Science.
[62] S. J. Flint,et al. Site-specific oligonucleotide binding represses transcription of the human c-myc gene in vitro. , 1988, Science.
[63] K Walsh,et al. MyoD binds to the guanine tetrad nucleic acid structure. , 1992, The Journal of biological chemistry.
[64] G. Siemeister,et al. Sp1 recognition sites in the proximal promoter of the human vascular endothelial growth factor gene are essential for platelet-derived growth factor-induced gene expression , 1997, Oncogene.
[65] Ove Sten-Knudsen,et al. Biological membranes : theory of transport, potentials and electrical impulses , 2002 .
[66] John B. Shoven,et al. I , Edinburgh Medical and Surgical Journal.
[67] S. Balasubramanian,et al. DNA Quadruplexes and Gene Regulation , 2006 .
[68] D. Patel,et al. Solution structure of the Tetrahymena telomeric repeat d(T2G4)4 G-tetraplex. , 1994, Structure.
[69] L. Hurley,et al. Formation of pseudosymmetrical G-quadruplex and i-motif structures in the proximal promoter region of the RET oncogene. , 2007, Journal of the American Chemical Society.
[70] S. J. Flint,et al. A nuclease-hypersensitive element of the human c-myc promoter interacts with a transcription initiation factor , 1989, Molecular and cellular biology.
[71] Jeffery T. Davis. G-Quartets 40 Years Later: From 5′-GMP to Molecular Biology and Supramolecular Chemistry , 2004 .
[72] E. Henderson,et al. A protein from Tetrahymena thermophila that specifically binds parallel-stranded G4-DNA. , 1994, Biochemistry.
[73] R. Tauler,et al. Solution equilibria of the i-motif-forming region upstream of the B-cell lymphoma-2 P1 promoter. , 2007, Biochimie.
[74] Stephen Neidle,et al. A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene. , 2006, Biochemistry.
[75] S. Balasubramanian,et al. Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: small molecule regulation of c-kit oncogene expression. , 2007, Journal of the American Chemical Society.
[76] D. Bonthron,et al. Platelet-derived growth factor A-chain gene transcription is mediated by positive and negative regulatory regions in the promoter. , 1994, The Biochemical journal.
[77] R. Wells,et al. Non-B DNA conformations, mutagenesis and disease. , 2007, Trends in biochemical sciences.
[78] K. Anderson,et al. Telomerase inhibition and cell growth arrest by G-quadruplex interactive agent in multiple myeloma. , 2003, Molecular cancer therapeutics.
[79] G. Krystal,et al. Selective Sp1 binding is critical for maximal activity of the human c-kit promoter. , 1998, Blood.
[80] M. Katahira,et al. Intramolecular Higher Order Packing of Parallel Quadruplexes Comprising a G:G:G:G Tetrad and a G(:A):G(:A):G(:A):G Heptad of GGA Triplet Repeat DNA* , 2003, Journal of Biological Chemistry.
[81] T. Simonsson,et al. G-Quadruplex DNA Structures Variations on a Theme , 2001, Biological chemistry.
[82] T. Deuel,et al. Functional analysis of the human platelet-derived growth factor A-chain promoter region. , 1992, The Journal of biological chemistry.
[83] R. Shafer,et al. Biological aspects of DNA/RNA quadruplexes , 2000, Biopolymers.
[84] E. Raymond,et al. Effects of cationic porphyrins as G-quadruplex interactive agents in human tumor cells. , 1999, Cancer research.
[85] M. Katahira,et al. An intramolecular quadruplex of (GGA)(4) triplet repeat DNA with a G:G:G:G tetrad and a G(:A):G(:A):G(:A):G heptad, and its dimeric interaction. , 2001, Journal of molecular biology.
[86] Stephen Neidle,et al. Putative DNA quadruplex formation within the human c-kit oncogene. , 2005, Journal of the American Chemical Society.
[87] M. Gordon,et al. Renal cell carcinoma: rationale and development of therapeutic inhibitors of angiogenesis. , 2004, Hematology/oncology clinics of North America.
[88] D. Davies,et al. Helix formation by guanylic acid. , 1962, Proceedings of the National Academy of Sciences of the United States of America.
[89] S. Berberich,et al. PuF/NM23-H2/NDPK-B transactivates a human c-myc promoter-CAT gene via a functional nuclease hypersensitive element. , 1995, Oncogene.
[90] Vijay Gokhale,et al. Design and synthesis of an expanded porphyrin that has selectivity for the c-MYC G-quadruplex structure. , 2005, Journal of the American Chemical Society.
[91] P. Bolton,et al. Functional and dysfunctional roles of quadruplex DNA in cells. , 2001, Chemistry & biology.
[92] O. Kranenburg,et al. The KRAS oncogene: past, present, and future. , 2005, Biochimica et biophysica acta.
[93] D. Bearss,et al. The Cationic Porphyrin TMPyP 4 Down-Regulates c-MYC and Human Telomerase Reverse Transcriptase Expression and Inhibits Tumor Growth in Vivo 1 , 2002 .
[94] J. V. Moran,et al. Initial sequencing and analysis of the human genome. , 2001, Nature.
[95] S. Pelengaris,et al. The c-MYC oncoprotein as a treatment target in cancer and other disorders of cell growth , 2003, Expert opinion on therapeutic targets.
[96] D. Chao,et al. BCL-2 family: regulators of cell death. , 1998, Annual review of immunology.
[97] D. V. Von Hoff,et al. Drug targeting of the c-MYC promoter to repress gene expression via a G-quadruplex silencer element. , 2006, Seminars in oncology.
[98] J. Shklover,et al. MyoD uses overlapping but distinct elements to bind E-box and tetraplex structures of regulatory sequences of muscle-specific genes , 2007, Nucleic acids research.
[99] Daekyu Sun,et al. Evidence for the presence of a guanine quadruplex forming region within a polypurine tract of the hypoxia inducible factor 1alpha promoter. , 2005, Biochemistry.
[100] A. Chan,et al. Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivatives. , 2007, Journal of medicinal chemistry.
[101] International Human Genome Sequencing Consortium. Finishing the euchromatic sequence of the human genome , 2004 .
[102] F. Agou,et al. Single Strand DNA Specificity Analysis of Human Nucleoside Diphosphate Kinase B* , 1999, The Journal of Biological Chemistry.
[103] T. Liesegang. A physical map of the human genome. The International Human Genome Mapping Consortium.∗ Nature 2001;409:934–941. , 2001 .
[104] M. Fukayama,et al. C‐kit Gene Abnormalities in Gastrointestinal Stromal Tumors (Tumors of Interstitial Cells of Cajal) , 1999, Japanese journal of cancer research : Gann.
[105] Alastair I.H. Murchie,et al. Retinoblastoma susceptibility genes contain 5' sequences with a high propensity to form guanine-tetrad structures , 1992, Nucleic Acids Res..
[106] D. Haussler,et al. A physical map of the human genome , 2001, Nature.
[107] B. Trask,et al. A High-Resolution Radiation Hybrid Map of the Human Genome Draft Sequence , 2001, Science.
[108] A. Varki,et al. Thoughts on the Future of Great Ape Research , 2005, Science.
[109] F. Crick,et al. Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid , 1974, Nature.
[110] T. Simonsson,et al. A nuclease hypersensitive element in the human c-myc promoter adopts several distinct i-tetraplex structures. , 2000, Biochemical and biophysical research communications.
[111] D. Langley,et al. Selective interactions of cationic porphyrins with G-quadruplex structures. , 2001, Journal of the American Chemical Society.
[112] S. Pelengaris,et al. The many faces of c-MYC. , 2003, Archives of biochemistry and biophysics.
[113] J. R. Williamson,et al. G-quartet structures in telomeric DNA. , 1994, Annual review of biophysics and biomolecular structure.
[114] R. Memmott,et al. A novel G-quadruplex-forming GGA repeat region in the c-myb promoter is a critical regulator of promoter activity , 2008, Nucleic acids research.
[115] D. Thiele,et al. Four-stranded nucleic acid structures 25 years later: from guanosine gels to telomer DNA. , 1990, Journal of biomolecular structure & dynamics.
[116] D. Goodsell. The molecular perspective: VEGF and angiogenesis. , 2002, The oncologist.
[117] Yan Lin,et al. Greglist: a database listing potential G-quadruplex regulated genes , 2007, Nucleic Acids Res..
[118] K. Itakura,et al. Binding of THZif-1, a MAZ-like Zinc Finger Protein to the Nuclease-hypersensitive Element in the Promoter Region of the c-MYC Protooncogene* , 1996, The Journal of Biological Chemistry.
[119] G. Parkinson,et al. Sequence occurrence and structural uniqueness of a G-quadruplex in the human c-kit promoter , 2007, Nucleic acids research.
[120] A. Phan,et al. Propeller-type parallel-stranded G-quadruplexes in the human c-myc promoter. , 2004, Journal of the American Chemical Society.
[121] D. V. Von Hoff,et al. Design and synthesis of fluoroquinophenoxazines that interact with human telomeric G-quadruplexes and their biological effects. , 2001, Molecular cancer therapeutics.
[122] Napoleone Ferrara,et al. Vascular endothelial growth factor: basic science and clinical progress. , 2004, Endocrine reviews.
[123] A. Patel,et al. myc function and regulation. , 1992, Annual review of biochemistry.
[124] Nancy D Perrier,et al. RET proto-oncogene: a review and update of genotype-phenotype correlations in hereditary medullary thyroid cancer and associated endocrine tumors. , 2005, Thyroid : official journal of the American Thyroid Association.
[125] T. Tomonaga,et al. Activating transcription from single stranded DNA. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[126] H. Deng,et al. Selective localization and rotational immobilization of univalent cations on quadruplex DNA. , 1993, Biochemistry.
[127] J. Feigon,et al. Multistranded DNA structures. , 1999, Current opinion in structural biology.
[128] R. Wells,et al. Non-B DNA Conformations, Genomic Rearrangements, and Human Disease* , 2004, Journal of Biological Chemistry.
[129] C. Griffin,et al. Expression of the c-myb oncogene in human small cell lung carcinoma. , 1985, Cancer research.
[130] P. Pečinka,et al. DNA tetraplex formation in the control region of c-myc. , 1998, Nucleic acids research.
[131] Structural and functional characterizations of the G-quartet and i-motif elements in retinoblastoma susceptibility genes (Rb). , 2005, Nucleic acids symposium series.
[132] M. Murphy,et al. An S1 nuclease-sensitive homopurine/homopyrimidine domain in the c-Ki-ras promoter interacts with a nuclear factor. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[133] Shankar Balasubramanian,et al. A sequence-independent study of the influence of short loop lengths on the stability and topology of intramolecular DNA G-quadruplexes. , 2008, Biochemistry.
[134] T. Cech,et al. Monovalent cation-induced structure of telomeric DNA: The G-quartet model , 1989, Cell.
[135] L. M. Facchini,et al. The molecular role of Myc in growth and transformation: recent discoveries lead to new insights , 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.