论文信息 - Complexes de polypeptides cbl-b et methodes associees

Complexes de polypeptides cbl-b et methodes associees

L'invention concerne des nouveaux complexes de polypeptides Cbl-b et des proteines associees a Cbl-b. L'invention concerne egalement des methodes et des compositions destinees au traitement de maladies liees a Cbl-b, telles que des troubles viraux.

D. Taglicht | H. Barr | S. Tuvia | I. Alroy | Yuval Reiss

[1] C. Elly,et al. Cbl-b, a RING-type E3 Ubiquitin Ligase, Targets Phosphatidylinositol 3-Kinase for Ubiquitination in T Cells* , 2001, The Journal of Biological Chemistry.

[2] M. Barbacid,et al. Cbl-b, a member of the Sli-1/c-Cbl protein family, inhibits Vav-mediated c-Jun N-terminal kinase activation , 1997, Oncogene.