Celastrus Orbiculatus Thunb Extract Targeting DJ-1 Inhibits Non-Small-Cell Lung Cancer Invasion and Metastasis Through Mitochondrial-Induced ROS Accumulation

[1]  A. Jemal,et al.  Cancer statistics, 2023 , 2023, CA: a cancer journal for clinicians.

[2]  Ying Cheng,et al.  Toripalimab Plus Chemotherapy for Patients With Treatment-Naive Advanced Non–Small-Cell Lung Cancer: A Multicenter Randomized Phase III Trial (CHOICE-01) , 2022, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[3]  H. Ovaa,et al.  Chemical Toolkit for PARK7: Potent, Selective, and High-Throughput , 2022, Journal of medicinal chemistry.

[4]  M. Grãos,et al.  Modulation of signaling pathways by DJ-1: An updated overview , 2022, Redox biology.

[5]  O. Buneeva,et al.  DJ-1 Protein and Its Role in the Development of Parkinson’s Disease: Studies on Experimental Models , 2021, Biochemistry (Moscow).

[6]  S. Pauklin,et al.  ROS and TGFβ: from pancreatic tumour growth to metastasis , 2021, Journal of experimental & clinical cancer research : CR.

[7]  Yayun Qian,et al.  COE Inhibits Vasculogenic Mimicry by Targeting EphA2 in Hepatocellular Carcinoma, a Research Based on Proteomics Analysis , 2021, Frontiers in Pharmacology.

[8]  Liu Gaofeng,et al.  Traditional Chinese medicine and lung cancer--From theory to practice. , 2021, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[9]  A. Whitworth,et al.  DJ-1: A promising therapeutic candidate for ischemia-reperfusion injury , 2021, Redox biology.

[10]  N. Hattori,et al.  Identification of Disease-Associated Variants by Targeted Gene Panel Resequencing in Parkinson's Disease , 2020, Frontiers in Neurology.

[11]  Lei Zhou,et al.  Multidisciplinary and Comprehensive Chinese Medicine for Advanced Non-Small Cell Lung Cancer Patients: A Retrospective Study of 855 Cases , 2020, Chinese Journal of Integrative Medicine.

[12]  Yang Li,et al.  Artificial intelligence in gastric cancer: a systematic review , 2020, Journal of Cancer Research and Clinical Oncology.

[13]  E. Tan,et al.  Historical Perspective: Models of Parkinson’s Disease , 2020, International journal of molecular sciences.

[14]  Xiongwei Zhu,et al.  DJ-1 regulates the integrity and function of ER-mitochondria association through interaction with IP3R3-Grp75-VDAC1 , 2019, Proceedings of the National Academy of Sciences.

[15]  Q. Zhang,et al.  Traditional uses, secondary metabolites, and pharmacology of Celastrus species - a review. , 2019, Journal of ethnopharmacology.

[16]  Joel S. Bader,et al.  E-cadherin is required for metastasis in multiple models of breast cancer , 2019, Nature.

[17]  Li-Zhu Lin,et al.  Association between Chinese Medicine Therapy and Survival Outcomes in Postoperative Patients with NSCLC: A Multicenter, Prospective, Cohort Study , 2019, Chinese Journal of Integrative Medicine.

[18]  Li Tao,et al.  Cytotoxic abietane and kaurane diterpenoids from Celastrus orbiculatus , 2019, Journal of Natural Medicines.

[19]  K. Kerr,et al.  Comparing and contrasting predictive biomarkers for immunotherapy and targeted therapy of NSCLC , 2019, Nature Reviews Clinical Oncology.

[20]  Yitao Wang,et al.  DJ-1 promotes colorectal cancer progression through activating PLAGL2/Wnt/BMP4 axis , 2018, Cell Death & Disease.

[21]  Xia-Wei Zhang,et al.  Chinese Herbal Medicine for Advanced Non-Small-Cell Lung Cancer: A Systematic Review and Meta-Analysis. , 2018, The American journal of Chinese medicine.

[22]  J. Chan,et al.  Activation of endogenous antioxidants as a common therapeutic strategy against cancer, neurodegeneration and cardiovascular diseases: A lesson learnt from DJ-1. , 2015, Pharmacology & therapeutics.

[23]  Bo Yang,et al.  DJ-1 as a human oncogene and potential therapeutic target. , 2015, Biochemical pharmacology.

[24]  T. Mak,et al.  Modulation of oxidative stress as an anticancer strategy , 2013, Nature Reviews Drug Discovery.

[25]  A. M. van der Bliek,et al.  Mitochondrial Fission, Fusion, and Stress , 2012, Science.

[26]  J. Nunnari,et al.  Mitochondria: In Sickness and in Health , 2012, Cell.

[27]  S. Courtneidge,et al.  The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function , 2011, Nature Reviews Molecular Cell Biology.

[28]  Peng Huang,et al.  Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? , 2009, Nature Reviews Drug Discovery.

[29]  T. Mak,et al.  DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2 , 2006, Proceedings of the National Academy of Sciences.

[30]  M. Cameron Sullards,et al.  Oxidative Damage of DJ-1 Is Linked to Sporadic Parkinson and Alzheimer Diseases* , 2006, Journal of Biological Chemistry.

[31]  Wenbo Zhou,et al.  DJ-1 Up-regulates Glutathione Synthesis during Oxidative Stress and Inhibits A53T α-Synuclein Toxicity* , 2005, Journal of Biological Chemistry.

[32]  T. Mak,et al.  DJ-1, a novel regulator of the tumor suppressor PTEN. , 2005, Cancer cell.

[33]  Patrizia Rizzu,et al.  Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism , 2002, Science.

[34]  G. Di Trapani,et al.  The Multifaceted Roles of DJ-1 as an Antioxidant. , 2017, Advances in experimental medicine and biology.

[35]  Qiaojun He,et al.  DJ-1 as a Therapeutic Target Against Cancer. , 2017, Advances in experimental medicine and biology.

[36]  Liquid Biopsies Non-small-cell lung cancer , 2015, Nature Reviews Disease Primers.

[37]  V. A. Flørenes,et al.  Expression and clinical role of DJ-1, a negative regulator of PTEN, in ovarian carcinoma. , 2008, Human pathology.