Tetrandrine Inhibits Wnt/β-Catenin Signaling and Suppresses Tumor Growth of Human Colorectal Cancer
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T. He | Q. Shi | Jikun Shen | Yang Bi | H. Luu | Ni Tang | Jinyong Luo | R. Haydon | Jian-Li Gao | Stephanie H Kim | Xing Liu | Bai-Cheng He | Qing Luo | Yanhong Gao | Bing-qiang Zhang | E. Wagner | Ke-Qin Yang | Qixin Zhou | G. Luther | Enyi Huang | Yingming Zhao | Ning Hu | Linyuan Wang | Mi Li | Keqin Yang | Eric R. Wagner
[1] Baorui Liu,et al. Enhanced cytotoxicity and activation of ROS-dependent c-Jun NH2-terminal kinase and caspase-3 by low doses of tetrandrine-loaded nanoparticles in Lovo cells--a possible Trojan strategy against cancer. , 2010, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
[2] T. He,et al. TGFβ/BMP Type I Receptors ALK1 and ALK2 Are Essential for BMP9-induced Osteogenic Signaling in Mesenchymal Stem Cells* , 2010, The Journal of Biological Chemistry.
[3] T. He,et al. Synergistic Antitumor Effect of the Activated PPARγ and Retinoid Receptors on Human Osteosarcoma , 2010, Clinical Cancer Research.
[4] Yun Chen,et al. Tetrandrine induces apoptosis and growth suppression of colon cancer cells in mice. , 2010, Cancer letters.
[5] T. He,et al. BMP‐9‐induced osteogenic differentiation of mesenchymal progenitors requires functional canonical Wnt/β‐catenin signalling , 2009, Journal of cellular and molecular medicine.
[6] Yun Chen,et al. Tetrandrine suppresses tumor growth and angiogenesis of gliomas in rats , 2009, International journal of cancer.
[7] D. Newman,et al. Impact of natural products on developing new anti-cancer agents. , 2009, Chemical reviews.
[8] T. He,et al. Establishment and characterization of a new highly metastatic human osteosarcoma cell line , 2009, Clinical & Experimental Metastasis.
[9] M. Cho,et al. Synergistic effect of ERK inhibition on tetrandrine-induced apoptosis in A549 human lung carcinoma cells , 2009, Journal of veterinary science.
[10] T. He,et al. Hey1 Basic Helix-Loop-Helix Protein Plays an Important Role in Mediating BMP9-induced Osteogenic Differentiation of Mesenchymal Progenitor Cells* , 2009, Journal of Biological Chemistry.
[11] A. Montag,et al. Osteogenic BMPs promote tumor growth of human osteosarcomas that harbor differentiation defects , 2008, Laboratory Investigation.
[12] Baorui Liu,et al. Anticancer effect of tetrandrine on primary cancer cells isolated from ascites and pleural fluids. , 2008, Cancer letters.
[13] T. He,et al. S100A6 Expression and Function in Human Osteosarcoma , 2008, Clinical orthopaedics and related research.
[14] R. Shao,et al. Involvement of PI3K/AKT/GSK3ß pathway in tetrandrine-induced G1 arrest and apoptosis , 2008, Cancer biology & therapy.
[15] M. Nomura,et al. Inhibition of tetrandrine on epidermal growth factor-induced cell transformation and its signal transduction. , 2007, Anticancer research.
[16] T. He,et al. Wnt signaling and human diseases: what are the therapeutic implications? , 2007, Laboratory Investigation.
[17] A. Montag,et al. CCN1/Cyr61 Is Regulated by the Canonical Wnt Signal and Plays an Important Role in Wnt3A-Induced Osteoblast Differentiation of Mesenchymal Stem Cells , 2006, Molecular and Cellular Biology.
[18] F. Gao,et al. Combination of tetrandrine as a potential-reversing agent with daunorubicin, etoposide and cytarabine for the treatment of refractory and relapsed acute myelogenous leukemia. , 2006, Leukemia research.
[19] C. Heizmann,et al. Increased expression of S100A6 is associated with decreased metastasis and inhibition of cell migration and anchorage independent growth in human osteosarcoma. , 2005, Cancer letters.
[20] E. Chu,et al. Current therapies for advanced colorectal cancer. , 2005, Oncology.
[21] F. Koehn,et al. The evolving role of natural products in drug discovery , 2005, Nature Reviews Drug Discovery.
[22] A. Montag,et al. Connective Tissue Growth Factor (CTGF) Is Regulated by Wnt and Bone Morphogenetic Proteins Signaling in Osteoblast Differentiation of Mesenchymal Stem Cells* , 2004, Journal of Biological Chemistry.
[23] Y. Pommier,et al. Tetrandrine Induces Early G1 Arrest in Human Colon Carcinoma Cells by Down-Regulating the Activity and Inducing the Degradation of G1-S–Specific Cyclin-Dependent Kinases and by Inducing p53 and p21Cip1 , 2004, Cancer Research.
[24] C. Iadecola,et al. Herbal alkaloid tetrandrine: fron an ion channel blocker to inhibitor of tumor proliferation. , 2004, Trends in pharmacological sciences.
[25] Seon-Hee Oh,et al. Induction of apoptosis in human hepatoblastoma cells by tetrandrine via caspase-dependent Bid cleavage and cytochrome c release. , 2003, Biochemical pharmacology.
[26] J. Szatkowski,et al. Tyrosine kinase inhibitor STI-571/Gleevec down-regulates the beta-catenin signaling activity. , 2003, Cancer letters.
[27] A. Montag,et al. Cytoplasmic and/or nuclear accumulation of the β‐catenin protein is a frequent event in human osteosarcoma , 2002, International journal of cancer.
[28] Yung-Hyun Choi,et al. Tetrandrine-induced cell cycle arrest and apoptosis in A549 human lung carcinoma cells. , 2002, International journal of oncology.
[29] Hongwei Cheng,et al. Fluorescence-Based Functional Assay for Wnt/β-Catenin Signaling Activity , 2002 .
[30] K. Kinzler,et al. Targeted inactivation of CTNNB1 reveals unexpected effects of β-catenin mutation , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[31] A. Montag,et al. Nuclear receptor agonists as potential differentiation therapy agents for human osteosarcoma. , 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.
[32] John Mann,et al. Natural products in cancer chemotherapy: past, present and future , 2002, Nature Reviews Cancer.
[33] A. Sparks,et al. Identification of c-MYC as a target of the APC pathway. , 1998, Science.
[34] M. Ishiyama,et al. A combined assay of cell viability and in vitro cytotoxicity with a highly water-soluble tetrazolium salt, neutral red and crystal violet. , 1996, Biological & pharmaceutical bulletin.
[35] K. Kinzler,et al. Lessons from Hereditary Colorectal Cancer , 1996, Cell.
[36] D. Himmel,et al. Interaction of tetrandrine with slowly inactivating calcium channels. Characterization of calcium channel modulation by an alkaloid of Chinese medicinal herb origin. , 1988, The Journal of biological chemistry.
[37] L. Chiang,et al. Antiproliferative and apoptotic effects of tetrandrine on different human hepatoma cell lines. , 2006, The American journal of Chinese medicine.
[38] A. Montag,et al. An Orthotopic Model of Human Osteosarcoma Growth and Spontaneous Pulmonary Metastasis , 2005, Clinical & Experimental Metastasis.
[39] Q. Zhou,et al. Fluorescence-based functional assay for Wnt/beta-catenin signaling activity. , 2002, BioTechniques.
[40] K. Kinzler,et al. Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation. , 2002, Proceedings of the National Academy of Sciences of the United States of America.