Directed Evolution : Novel and Improved Enzymes
暂无分享,去创建一个
[1] Marc Ostermeier,et al. A combinatorial approach to hybrid enzymes independent of DNA homology , 1999, Nature Biotechnology.
[2] Jared R. Leadbetter,et al. Dual selection enhances the signaling specificity of a variant of the quorum-sensing transcriptional activator LuxR , 2006, Nature Biotechnology.
[3] Min Li. Applications of display technology in protein analysis , 2000, Nature Biotechnology.
[4] T. Terwilliger,et al. Engineering soluble proteins for structural genomics , 2002, Nature Biotechnology.
[5] Huimin Zhao,et al. Directed evolution of enzymes and biosynthetic pathways. , 2006, Current opinion in microbiology.
[6] W. Stemmer. Rapid evolution of a protein in vitro by DNA shuffling , 1994, Nature.
[7] S. Kauffman,et al. Towards a general theory of adaptive walks on rugged landscapes. , 1987, Journal of theoretical biology.
[8] W. Stemmer,et al. DNA shuffling of a family of genes from diverse species accelerates directed evolution , 1998, Nature.
[9] Gerd Folkers,et al. Directed evolution of thymidine kinase for AZT phosphorylation using DNA family shuffling , 1999, Nature Biotechnology.
[10] Huimin Zhao,et al. Recent advances in biocatalysis by directed enzyme evolution. , 2006, Combinatorial chemistry & high throughput screening.
[11] Costas D. Maranas,et al. Computational challenges in combinatorial library design for protein engineering , 2004 .
[12] F. Arnold. Design by Directed Evolution , 1998 .
[13] G. Gilardi,et al. Directed evolution of enzymes for product chemistry. , 2004, Natural product reports.
[14] F. Arnold,et al. Optimizing industrial enzymes by directed evolution. , 1997, Advances in biochemical engineering/biotechnology.
[15] C. Schmidt-Dannert,et al. Alteration of product specificity of Aeropyrum pernix farnesylgeranyl diphosphate synthase (Fgs) by directed evolution. , 2004, Protein engineering, design & selection : PEDS.
[16] Mark J. Olsen,et al. Function-based isolation of novel enzymes from a large library , 2000, Nature Biotechnology.
[17] Gavin J. Williams,et al. Modifying the stereochemistry of an enzyme-catalyzed reaction by directed evolution , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[18] C D Maranas,et al. Creating multiple-crossover DNA libraries independent of sequence identity , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[19] Howard M. Shapiro,et al. Practical Flow Cytometry , 1985 .
[20] C. Schmidt-Dannert. Directed evolution of single proteins, metabolic pathways, and viruses. , 2001, Biochemistry.
[21] Matthias Paschke,et al. Phage display systems and their applications , 2006, Applied Microbiology and Biotechnology.
[22] David R. Liu,et al. Nucleic acid evolution and minimization by nonhomologous random recombination , 2002, Nature Biotechnology.
[23] Huimin Zhao,et al. Directed evolution of specific receptor-ligand pairs for use in the creation of gene switches. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[24] T. Eggert,et al. Enantioselective biocatalysis optimized by directed evolution. , 2004, Current opinion in biotechnology.
[25] F. Arnold,et al. Directed evolution of a thermostable esterase. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[26] 大植 慎也. Redesigning the substrate specificity of an enzyme by cumulative effects of the mutations of non-active site residues , 1999 .
[27] G. Winter,et al. A strategy for the isolation of catalytic activities from repertoires of enzymes displayed on phage. , 1999, Journal of molecular biology.
[28] Huimin Zhao,et al. Directed Evolution of a Thermostable Phosphite Dehydrogenase for NAD(P)H Regeneration , 2005, Applied and Environmental Microbiology.
[29] Frances H. Arnold,et al. Directed enzyme evolution : screening and selection methods , 2003 .
[30] Huimin Zhao,et al. Directed Evolution: Novel and Improved Enzymes , 2008 .
[31] W. Stemmer,et al. Directed evolution of proteins by exon shuffling , 2001, Nature Biotechnology.
[32] Loren L Looger,et al. Computational Design of a Biologically Active Enzyme , 2004, Science.
[33] Frances H. Arnold,et al. Molecular evolution by staggered extension process (StEP) in vitro recombination , 1998, Nature Biotechnology.
[34] H. Suenaga,et al. Enhanced degradation of polychlorinated biphenyls by directed evolution of biphenyl dioxygenase , 1998, Nature Biotechnology.
[35] Dan S. Tawfik,et al. Directed evolution of an extremely fast phosphotriesterase by in vitro compartmentalization , 2003, The EMBO journal.
[36] F. Arnold,et al. Evolving strategies for enzyme engineering. , 2005, Current opinion in structural biology.
[37] Volker Sieber,et al. Libraries of hybrid proteins from distantly related sequences , 2001, Nature Biotechnology.
[38] J. Liao,et al. Alteration of Product Specificity of Rhodobacter sphaeroides Phytoene Desaturase by Directed Evolution* , 2001, The Journal of Biological Chemistry.
[39] Thomas E. Ferrin,et al. Designed divergent evolution of enzyme function , 2006, Nature.
[40] Marc Ostermeier,et al. Directed evolution of protein switches and their application to the creation of ligand-binding proteins. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[41] Sung-Hun Nam,et al. Design and Evolution of New Catalytic Activity with an Existing Protein Scaffold , 2006, Science.
[42] D. Goeddel,et al. A method for random mutagenesis of a defined DNA segment using a modified polymerase chain reaction , 1989 .
[43] D. Mills,et al. An extracellular Darwinian experiment with a self-duplicating nucleic acid molecule. , 1967, Proceedings of the National Academy of Sciences of the United States of America.
[44] S. Benkovic,et al. Rapid generation of incremental truncation libraries for protein engineering using alpha-phosphothioate nucleotides. , 2001, Nucleic acids research.
[45] J. Reymond,et al. High-throughput screening for biocatalysts. , 2001, Current opinion in biotechnology.
[46] P G Schultz,et al. A method for directed evolution and functional cloning of enzymes. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[47] G. Winter,et al. A method for the selection of catalytic activity using phage display and proximity coupling. , 1999, Angewandte Chemie.
[48] J. Seffernick,et al. Novel enzyme activities and functional plasticity revealed by recombining highly homologous enzymes. , 2001, Chemistry & biology.
[49] Dan S. Tawfik,et al. Man-made cell-like compartments for molecular evolution , 1998, Nature Biotechnology.
[50] M. Nardini,et al. Directed evolution of an enantioselective lipase. , 2000, Chemistry & biology.
[51] Jon E. Ness,et al. DNA shuffling of subgenomic sequences of subtilisin , 1999, Nature Biotechnology.
[52] Dan S. Tawfik,et al. Evolution of new protein topologies through multistep gene rearrangements , 2006, Nature Genetics.
[53] Jeremy Minshull,et al. Evolutionary potential of (beta/alpha)8-barrels: functional promiscuity produced by single substitutions in the enolase superfamily. , 2003, Biochemistry.
[54] Christian Wandrey,et al. Industrial Biocatalysis: Past, Present, and Future , 2000 .
[55] Andreas Vogel,et al. Expanding the range of substrate acceptance of enzymes: combinatorial active-site saturation test. , 2005, Angewandte Chemie.
[56] Anthony J. Wilkinson,et al. Protein engineering 20 years on , 2002, Nature Reviews Molecular Cell Biology.
[57] G. Grisetti,et al. Further Reading , 1984, IEEE Spectrum.
[58] A. Griffiths,et al. High-throughput screening of enzyme libraries: in vitro evolution of a beta-galactosidase by fluorescence-activated sorting of double emulsions. , 2005, Chemistry & biology.
[59] Frances H Arnold,et al. Why high-error-rate random mutagenesis libraries are enriched in functional and improved proteins. , 2004, Journal of molecular biology.
[60] T. Terwilliger,et al. Rapid protein-folding assay using green fluorescent protein , 1999, Nature Biotechnology.
[61] Dan S. Tawfik,et al. The 'evolvability' of promiscuous protein functions , 2005, Nature Genetics.