Myocardial velocity gradients detected by Doppler imaging.

Using a scanner whose colour Doppler mode has been adapted to display tissue motion (instead of blood flow), velocity gradients have been detected across the myocardium. A velocity gradient is a gradual spatial change in the value of velocity estimates. Velocity gradients have potential for assessing regional myocardial contractility. 28 M-mode scans were performed on nine normal volunteers at different locations in the left-ventricle posterior wall. In each case simultaneous Doppler M-mode and pulse-echo M-mode images were obtained. Doppler velocity gradient (DVG) was calculated from Doppler M-mode images and rate of change of wall thickness (RCWT) was calculated from pulse-echo M-mode images. In all Doppler M-mode images statistically significant velocity gradients were observed. In all but one scan, cyclically consistent peaks in DVG occur relative to the electrocardiogram waveform. 99% of systolic and 89% of early diastolic peaks in RCWT have a corresponding peak in DVG. Velocity gradients are consistent with wall thickness changes, suggesting that they have potential for assessment of myocardial contractility.

[1]  H J Gelberg Regional left ventricular wall motion. , 1980, Circulation.

[2]  G M Hutchins,et al.  Two‐dimensional Echocardiography and Infarct Size: Relationship of Regional Wall Motion and Thickening to the Extent of Myocardial Infarction in the Dog , 1981, Circulation.

[3]  A E Becker,et al.  Left ventricular fibre architecture in man. , 1981, British heart journal.

[4]  G. Maurer,et al.  Quantitation of Regional Cardiac Function by Two–dimensional Echocardiography: I. Patterns of Contraction in the Normal Left Ventricle , 1983, Circulation.

[5]  M. Nieminen,et al.  Quantitative detection of regional left ventricular contraction abnormalities by 2-dimensional echocardiography. Comparison of myocardial thickening and thinning and endocardial motion in a canine model. , 1983, The American journal of cardiology.

[6]  K. Gallagher,et al.  Decreased systolic wall thickening in myocardium adjacent to ischemic zones in conscious swine during brief coronary artery occlusion. , 1984, American heart journal.

[7]  J. Ross,et al.  Ischemic myocardial dysfunction assessed by temporal Fourier transform of regional myocardial wall thickening. , 1987, American heart journal.

[8]  G R Sutherland,et al.  Colour Doppler velocity imaging of the myocardium. , 1992, Ultrasound in medicine & biology.

[9]  G. Heusch,et al.  Time course and mechanisms of contractile dysfunction during acute myocardial ischemia. , 1993, Circulation.

[10]  G. Sutherland,et al.  Myocardial imaging by color-Doppler coded velocity mapping — from regional contraction to tissue characterization? , 1993 .

[11]  G. Sutherland,et al.  Potential applications of color-Doppler imaging of the myocardium in assessing contractility and perfusion , 1993 .