Mucosal imaging advanced technologies in the gastrointestinal tract

Abstract The use of advanced imaging technologies to enhance visualization the gastrointestinal mucosa has evolved from being an experimental tool to a valuable adjunct in diagnostic and therapeutic endoscopy. Digital chromoendoscopy including narrow band imaging (NBI) has been incorporated into standard endoscopy systems as a practical instrument used to enhance the mucosal surface and microvasculature. NBI is now routinely used to evaluate mucosal irregularities associated with Barrett's esophagus dysplasia. A recent review of the literature suggests that NBI can be used to evaluate colorectal polyps and its use may even change our clinical management of diminutive polyps. Other technologies, such as confocal laser endomicroscopy (CLE) and optical coherence tomography require independent imaging systems with probes that can be deployed through an endoscope׳s instrument channel. The incorporation of these technologies into clinical practice has been limited by cost and need for expertise in image interpretation. High-magnification imaging with CLE can evaluate mucosal changes that are both sensitive and specific to various disease processes. CLE probes have a small field of view that makes evaluation of large areas of the gastrointestinal tract time consuming. A second-generation optical coherence tomography system also known as volumetric laser endomicroscopy is capable of wide-field cross-sectional imaging of the human esophagus. New technologies, including second-generation digital chromoendoscopy blue-laser imaging are currently under study. Development and utilization of advanced imaging technologies has been critical in the rapid pace of advances in diagnostic and therapeutic endoscopy in the past decade.

[1]  Mari Mino-Kenudson,et al.  Identifying intestinal metaplasia at the squamocolumnar junction by using optical coherence tomography. , 2007, Gastrointestinal endoscopy.

[2]  Michael Vieth,et al.  In vivo histology of Barrett's esophagus and associated neoplasia by confocal laser endomicroscopy. , 2006, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[3]  X. Zuo,et al.  Diagnostic value of confocal laser endomicroscopy for gastric superficial cancerous lesions , 2010, Gut.

[4]  C. Hawkey,et al.  Narrow band imaging for characterization of high grade dysplasia and specialized intestinal metaplasia in Barrett’s esophagus: a meta-analysis , 2010, Endoscopy.

[5]  Shinji Tanaka,et al.  Endoscopic prediction of deep submucosal invasive carcinoma: validation of the narrow-band imaging international colorectal endoscopic (NICE) classification. , 2013, Gastrointestinal endoscopy.

[6]  M. Wallace,et al.  Accuracy of real-time vs. blinded offline diagnosis of neoplastic colorectal polyps using probe-based confocal laser endomicroscopy: a pilot study , 2012, Endoscopy.

[7]  M. Wallace,et al.  Miami classification for probe-based confocal laser endomicroscopy , 2011, Endoscopy.

[8]  Vani Konda,et al.  ASGE Technology Committee systematic review and meta-analysis assessing the ASGE PIVI thresholds for adopting real-time endoscopic assessment of the histology of diminutive colorectal polyps. , 2015, Gastrointestinal endoscopy.

[9]  M. Leja,et al.  The accuracy of flexible spectral imaging colour enhancement for the diagnosis of gastric intestinal metaplasia: do we still need histology to select individuals at risk for adenocarcinoma? , 2014, European journal of gastroenterology & hepatology.

[10]  S. Staibano,et al.  In vivo characterisation of superficial colorectal neoplastic lesions with high-resolution probe-based confocal laser endomicroscopy in combination with video-mosaicing: a feasibility study to enhance routine endoscopy. , 2010, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

[11]  Shinji Tanaka,et al.  Validation of a simple classification system for endoscopic diagnosis of small colorectal polyps using narrow-band imaging. , 2012, Gastroenterology.

[12]  Haitao Wang,et al.  The Nerve Growth Factor Signaling and Its Potential as Therapeutic Target for Glaucoma , 2014, BioMed research international.

[13]  Douglas K Rex,et al.  Narrow-band imaging without optical magnification for histologic analysis of colorectal polyps. , 2009, Gastroenterology.

[14]  R. Kiesslich,et al.  Local barrier dysfunction identified by confocal laser endomicroscopy predicts relapse in inflammatory bowel disease , 2011, Gut.

[15]  S. Cross,et al.  Confocal chromoscopic endomicroscopy is superior to chromoscopy alone for the detection and characterisation of intraepithelial neoplasia in chronic ulcerative colitis , 2008, Gut.

[16]  P. Sharma,et al.  A multicenter validation of an endoscopic classification with narrow band imaging for gastric precancerous and cancerous lesions , 2012, Endoscopy.

[17]  Sharmila Anandasabapathy,et al.  In vivo endomicroscopy improves detection of Barrett's esophagus-related neoplasia: a multicenter international randomized controlled trial (with video). , 2014, Gastrointestinal endoscopy.

[18]  J. Bond.  Polyp guideline: diagnosis, treatment, and surveillance for patients with colorectal polyps , 2000, American Journal of Gastroenterology.

[19]  Gregory Zuccaro,et al.  In vivo colonoscopic optical coherence tomography for transmural inflammation in inflammatory bowel disease. , 2004, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[20]  Q Wang,et al.  Differentiation of colonic polyps by confocal laser endomicroscopy. , 2011, Endoscopy.

[21]  X. Zuo,et al.  Confocal endomicroscopy for in vivo prediction of completeness after endoscopic mucosal resection , 2011, Surgical Endoscopy.

[22]  Alan Barkun,et al.  SCENIC international consensus statement on surveillance and management of dysplasia in inflammatory bowel disease. , 2015, Gastrointestinal endoscopy.

[23]  R. Odze,et al.  Buried Metaplasia After Endoscopic Ablation of Barrett's Esophagus: A Systematic Review , 2011, The American Journal of Gastroenterology.

[24]  E. Dekker,et al.  Narrow-band imaging versus high-definition endoscopy for the diagnosis of neoplasia in ulcerative colitis. , 2011, Endoscopy.

[25]  Kenneth K Wang,et al.  Development of subsquamous high-grade dysplasia and adenocarcinoma after successful radiofrequency ablation of Barrett's esophagus. , 2012, Gastroenterology.

[26]  Xiu-Li Zuo,et al.  Classification of Inflammation Activity in Ulcerative Colitis by Confocal Laser Endomicroscopy , 2010, The American Journal of Gastroenterology.

[27]  Michael B Wallace,et al.  Real-time increased detection of neoplastic tissue in Barrett's esophagus with probe-based confocal laser endomicroscopy: final results of an international multicenter, prospective, randomized, controlled trial. , 2011, Gastrointestinal endoscopy.

[28]  Xiaojing Wu,et al.  Quantitative Diagnosis of Colorectal Polyps by Spectral Domain Optical Coherence Tomography , 2014, BioMed research international.

[29]  B E Bouma,et al.  Diagnosis of specialized intestinal metaplasia by optical coherence tomography. , 2001, Gastroenterology.

[30]  Anne-Fré Swager,et al.  Detection of buried Barrett's glands after radiofrequency ablation with volumetric laser endomicroscopy. , 2016, Gastrointestinal endoscopy.

[31]  O. Maeda,et al.  Confocal endomicroscopy in patients with ulcerative colitis , 2008, Journal of gastroenterology and hepatology.

[32]  Qin Huang,et al.  Characterization of buried glands before and after radiofrequency ablation by using 3-dimensional optical coherence tomography (with videos). , 2012, Gastrointestinal endoscopy.

[33]  Y. Bao,et al.  An Investigation of Cigarettes Smoking Behavior and Nicotine Dependence among Chinese Methamphetamine Users in Two Provinces , 2014, BioMed research international.

[34]  R. Kiesslich,et al.  Chromoscopy-guided endomicroscopy increases the diagnostic yield of intraepithelial neoplasia in ulcerative colitis. , 2007, Gastroenterology.

[35]  Marcia Irene Canto,et al.  Confocal laser endomicroscopy in Barrett's esophagus and endoscopically inapparent Barrett's neoplasia: a prospective, randomized, double-blind, controlled, crossover trial. , 2009, Gastrointestinal endoscopy.

[36]  H. Tajiri,et al.  High-definition endoscopy and magnifying endoscopy combined with narrow band imaging in gastric cancer. , 2010, Gastroenterology clinics of North America.

[37]  M. Leja,et al.  Systematic review of the diagnosis of gastric premalignant conditions and neoplasia with high-resolution endoscopic technologies , 2013, Scandinavian journal of gastroenterology.

[38]  Silvia Sanduleanu,et al.  In vivo diagnosis and classification of colorectal neoplasia by chromoendoscopy-guided confocal laser endomicroscopy. , 2010, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[39]  Kenneth K Wang,et al.  Updated Guidelines 2008 for the Diagnosis, Surveillance and Therapy of Barrett's Esophagus , 1998, The American Journal of Gastroenterology.

[40]  C. Lightdale,et al.  The safety of intravenous fluorescein for confocal laser endomicroscopy in the gastrointestinal tract , 2010, Alimentary pharmacology & therapeutics.

[41]  Mari Mino-Kenudson,et al.  Optical coherence tomography to identify intramucosal carcinoma and high-grade dysplasia in Barrett's esophagus. , 2006, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[42]  Sarah K. McGill,et al.  Narrow band imaging to differentiate neoplastic and non-neoplastic colorectal polyps in real time: a meta-analysis of diagnostic operating characteristics , 2013, Gut.

[43]  Paul Fockens,et al.  Standard endoscopy with random biopsies versus narrow band imaging targeted biopsies in Barrett's oesophagus: a prospective, international, randomised controlled trial , 2012, Gut.

[44]  Elena V. Zagaynova,et al.  Optical coherence tomography of the esophagus and proximal stomach in health and disease , 2001 .

[45]  T. Tong,et al.  Detection of Colorectal Adenoma by Narrow Band Imaging (HQ190) vs. High-Definition White Light Colonoscopy: A Randomized Controlled Trial , 2014, The American Journal of Gastroenterology.

[46]  K. Garsed,et al.  Narrow-band imaging with magnification in Barrett’s esophagus: validation of a simplified grading system of mucosal morphology patterns against histology , 2008, Endoscopy.

[47]  Charles J. Kahi,et al.  The American Society for Gastrointestinal Endoscopy PIVI (Preservation and Incorporation of Valuable Endoscopic Innovations) on real-time endoscopic assessment of the histology of diminutive colorectal polyps. , 2011, Gastrointestinal endoscopy.

[48]  L. Dinesen,et al.  Meta-analysis of narrow-band imaging versus conventional colonoscopy for adenoma detection. , 2012, Gastrointestinal Endoscopy.

[49]  A. Polglase,et al.  Confocal laser endoscopy for diagnosing intraepithelial neoplasias and colorectal cancer in vivo. , 2004, Gastroenterology.

[50]  Joseph A Izatt,et al.  Criteria for the diagnosis of dysplasia by endoscopic optical coherence tomography. , 2003, Gastrointestinal endoscopy.

[51]  Gregory Zuccaro,et al.  Ex vivo histology-correlated optical coherence tomography in the detection of transmural inflammation in Crohn's disease. , 2004, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[52]  S. Staibano,et al.  Diagnostic accuracy of confocal laser endomicroscopy in diagnosing dysplasia in patients affected by long-standing ulcerative colitis. , 2012, World journal of gastrointestinal endoscopy.

[53]  M. Vieth,et al.  Probe-based confocal laser endomicroscopy compared with standard four-quadrant biopsy for evaluation of neoplasia in Barrett’s esophagus , 2010, Endoscopy.

[54]  Michael B Wallace,et al.  Prospective, controlled tandem endoscopy study of narrow band imaging for dysplasia detection in Barrett's Esophagus. , 2008, Gastroenterology.

[55]  J. Bond.  Polyp Guideline: Diagnosis, Treatment, and Surveillance for Patients With Colorectal Polyps* , 2000 .

[56]  Angela Alibrandi,et al.  Optical Coherence Tomography Evaluation of Ulcerative Colitis: The Patterns and the Comparison with Histology , 2006, The American Journal of Gastroenterology.

[57]  Marlys Anderson,et al.  Comparative diagnostic performance of volumetric laser endomicroscopy and confocal laser endomicroscopy in the detection of dysplasia associated with Barrett's esophagus. , 2016, Gastrointestinal endoscopy.

[58]  X. Zuo,et al.  Confocal laser endomicroscopy for in vivo detection of gastric intestinal metaplasia: a randomized controlled trial , 2014, Endoscopy.

[59]  P. Fockens,et al.  Detection and classification of the mucosal and vascular patterns (mucosal morphology) in Barrett's esophagus by using narrow band imaging. , 2006, Gastrointestinal endoscopy.

[60]  B. Wiedenmann,et al.  Latest generation, wide-angle, high-definition colonoscopes increase adenoma detection rate. , 2012, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[61]  A. Bansal,et al.  The utility of a novel narrow band imaging endoscopy system in patients with Barrett's esophagus. , 2005, Gastrointestinal endoscopy.