Growth control by the retinoblastoma gene family.

[1]  J. Harbour,et al.  The Rb/E2F pathway: expanding roles and emerging paradigms. , 2000, Genes & development.

[2]  C. Sherr.  The Pezcoller lecture: cancer cell cycles revisited. , 2000, Cancer research.

[3]  K. Ichimura,et al.  Structure of the human retinoblastoma-related p107 gene and its intragenic deletion in a B-cell lymphoma cell line. , 2000, Gene.

[4]  C. Cinti,et al.  Genetic alterations disrupting the nuclear localization of the retinoblastoma-related gene RB2/p130 in human tumor cell lines and primary tumors. , 2000, Cancer research.

[5]  S. Pileri,et al.  Retinoblastoma-related p107 and pRb2/p130 proteins in malignant lymphomas: distinct mechanisms of cell growth control. , 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

[6]  A. Giordano,et al.  Differential expression of the retinoblastoma gene family members in choroidal melanoma: prognostic significance. , 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

[7]  T. Jacks,et al.  The retinoblastoma gene family: cousins with overlapping interests. , 1998, Trends in genetics : TIG.

[8]  A. Giordano,et al.  Expression of the retinoblastoma-related gene Rb2/p130 correlates with clinical outcome in endometrial cancer. , 1998, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[9]  A. Giordano,et al.  Differential expression of Rb2/p130 and p107 in normal human tissues and in primary lung cancer. , 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.

[10]  N. Tommerup,et al.  Loss of the retinoblastoma protein-related p130 protein in small cell lung carcinoma. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[11]  M. Strauss,et al.  The retinoblastoma protein: a master regulator of cell cycle, differentiation and apoptosis. , 1997, European journal of biochemistry.

[12]  D. Ribatti,et al.  RB1 oncosuppressor gene over-expression inhibits tumor progression and induces melanogenesis in metastatic melanoma cells. , 1996, Oncogene.

[13]  A. Giordano,et al.  Retinoblastoma protein family in cell cycle and cancer: A review , 1996, Journal of cellular biochemistry.

[14]  P. Starostik,et al.  Transcriptional repression and growth suppression by the p107 pocket protein , 1996, Molecular and cellular biology.

[15]  R. Beijersbergen,et al.  Cell cycle regulation by the retinoblastoma family of growth inhibitory proteins. , 1996, Biochimica et biophysica acta.

[16]  P. Dirks,et al.  Activity of the retinoblastoma family proteins, pRB, p107, and p130, during cellular proliferation and differentiation. , 1996, Critical reviews in biochemistry and molecular biology.

[17]  A. Giordano,et al.  Functional analysis of pRb2/p130 interaction with cyclins. , 1996, Cancer research.

[18]  P. Claudio,et al.  The Rb2/p130 gene product is a nuclear protein whose phosphorylation is cycle regulated , 1995, Journal of cellular biochemistry.

[19]  A. Floridi,et al.  The retinoblastoma gene product in acute myeloid leukemia: a possible involvement in promyelocytic leukemia. , 1995, Cancer research.

[20]  J. Bartek,et al.  Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16 , 1995, Nature.

[21]  R. Kerkhoven,et al.  Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes. , 1995, Genes & development.

[22]  R. Weinberg,et al.  The retinoblastoma protein and cell cycle control , 1995, Cell.

[23]  G. Skuse,et al.  Viral oncoprotein binding to pRB, p107, p130, and p300. , 1995, Virus research.

[24]  G. Condorelli,et al.  p130/pRb2 has growth suppressive properties similar to yet distinctive from those of retinoblastoma family members pRb and p107. , 1994, Cancer research.

[25]  M. Ewen,et al.  The cell cycle and the retinoblastoma protein family , 1994, Cancer and Metastasis Reviews.

[26]  F. Martelli,et al.  Defective human retinoblastoma protein identified by lack of interaction with the E1A oncoprotein. , 1994, Cancer research.

[27]  R. Weinberg,et al.  Tumor suppressor genes. , 1994, Current opinion in genetics & development.

[28]  W. Lee,et al.  The retinoblastoma gene product is a cell cycle-dependent, nuclear matrix-associated protein. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[29]  K. Klinga-Levan,et al.  The retinoblastoma-related gene, RB2, maps to human chromosome 16q12 and rat chromosome 19. , 1993, Oncogene.

[30]  R. Weinberg,et al.  Cell cycle-specific association of E2F with the p130 E1A-binding protein. , 1993, Genes & development.

[31]  A. Duncan,et al.  The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E. , 1993, Genes & development.

[32]  G. Hannon,et al.  Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins. , 1993, Genes & development.

[33]  A. Giordano,et al.  Cloning of a new member of the retinoblastoma gene family (pRb2) which binds to the E1A transforming domain. , 1993, Oncogene.

[34]  B. Gallie,et al.  A bipartite nuclear localization signal in the retinoblastoma gene product and its importance for biological activity , 1993, Molecular and cellular biology.

[35]  M. Ewen,et al.  Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein. , 1993, Genes & development.

[36]  K. Münger,et al.  Homologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteins , 1992, Journal of virology.

[37]  S. Reed,et al.  Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p107 and E2F in a temporally distinct manner. , 1992, Genes & development.

[38]  O. Olopade,et al.  Molecular analysis of deletions of the short arm of chromosome 9 in human gliomas. , 1992, Cancer research.

[39]  M. Ewen,et al.  Interaction between human cyclin A and adenovirus E1A-associated p107 protein. , 1992, Science.

[40]  R. Weinberg,et al.  Tumor suppressor genes. , 1991, Science.

[41]  Y. Qian,et al.  The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle , 1991, Cell.

[42]  E. Marsilio,et al.  The T/t common region of simian virus 40 large T antigen contains a distinct transformation-governing sequence , 1991, Journal of virology.

[43]  M. Ewen,et al.  Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein , 1991, Cell.

[44]  R. Weinberg,et al.  G1/S phosphorylation of the retinoblastoma protein is associated with an altered affinity for the nuclear compartment , 1991, Cell.

[45]  D. Rappolee,et al.  A single Cys706 to Phe substitution in the retinoblastoma protein causes the loss of binding to SV40 T antigen. , 1990, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[46]  E. Buckley,et al.  Oncogenic point mutations in the human retinoblastoma gene: their application to genetic counseling. , 1989, The New England journal of medicine.

[47]  David M. Livingston,et al.  The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element , 1989, Cell.

[48]  E. Harlow,et al.  The retinoblastoma protein is phosphorylated during specific phases of the cell cycle , 1989, Cell.

[49]  Phang-lang Chen,et al.  Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation , 1989, Cell.

[50]  N. Dyson,et al.  The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus , 1989, Cell.

[51]  K. Münger,et al.  The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. , 1989, Science.

[52]  Wen-Hwa Lee,et al.  SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene , 1988, Cell.

[53]  Stephen H. Friend,et al.  Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product , 1988, Nature.

[54]  Wen-Hwa Lee,et al.  The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity , 1987, Nature.

[55]  B R Franza,et al.  Association of adenovirus early-region 1A proteins with cellular polypeptides , 1986, Molecular and cellular biology.

[56]  K. Maruyama,et al.  Adenovirus E1A coding sequences that enable ras and pmt oncogenes to transform cultured primary cells , 1986, Molecular and cellular biology.

[57]  A. Ting,et al.  A Technique for Lymphocyte Preparation from Stored Heparinized Blood 1 , 1971, Vox sanguinis.

[58]  U. K. Laemmli,et al.  Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 , 1970, Nature.

[59]  C. Cinti,et al.  Expression of cell-cycle–associated proteins pRB2/p130 and p27kip1 in vulvar squamous cell carcinomas , 2001 .

[60]  C. Cinti,et al.  Mutations in the retinoblastoma-related gene RB2/p130 in primary nasopharyngeal carcinoma. , 2000, Cancer research.

[61]  M. Kasten,et al.  The RB family of cell cycle regulatory factors. , 1998, Journal of cellular biochemistry. Supplement.

[62]  A. Giordano,et al.  Simian virus 40-like DNA sequences and large-T antigen-retinoblastoma family protein pRb2/p130 interaction in human mesothelioma. , 1998, Developments in biological standardization.

[63]  A. Giordano,et al.  Cyclins, cyclin-dependent kinases and cdk inhibitors: implications in cell cycle control and cancer. , 1995, Critical reviews in eukaryotic gene expression.

[64]  D. Riley,et al.  The retinoblastoma protein: more than a tumor suppressor. , 1994, Annual review of cell biology.

[65]  W. Lee,et al.  C-terminal truncation of the retinoblastoma gene product leads to functional inactivation. , 1990, Proceedings of the National Academy of Sciences of the United States of America.