Olecranon Osteomyelitis due to Actinomyces meyeri: Report of a Culture-Proven Case

Actinomyces meyeri is a Gram positive, strict anaerobic bacterium, which was first described by Meyer in 1911. Primary actinomycotic osteomyelitis is rare and primarily affects the cervicofacial region, including mandible. We present an unusual case of osteomyelitis of a long bone combined with myoabscess due to A. meyeri. A 70-year-old man was admitted for pain and pus discharge of the right elbow. Twenty-five days before admission, he had hit his elbow against a table. MRI of the elbow showed a partial tear of the distal triceps tendon and myositis. He underwent open debridement and partial bone resection for the osteomyelitis of the olecranon. Biopsy showed no sulfur granules, but acute and chronic osteomyelitis. The excised tissue grew A. meyeri and Peptoniphilus asaccharolyticus. Intravenous ceftriaxone was administered and switched to oral amoxicillin. Infection of the extremities of actinomycosis often poses diagnostic difficulties, but it should not be neglected even when the characteristic pathologic findings are not present.

[1]  T. Russo Agents of Actinomycosis , 2015 .

[2]  H. Park,et al.  A Case of Disseminated Infection due to Actinomyces meyeri Involving Lung and Brain , 2014, Infection & chemotherapy.

[3]  L. Boussel,et al.  Actinomycosis: etiology, clinical features, diagnosis, treatment, and management , 2014, Infection and drug resistance.

[4]  V. Cope ACTINOMYCOSIS OF THE CENTRAL NERVOUS SYSTEM , 2013 .

[5]  D. Blair,et al.  Actinomyces meyeri infection: case report and review of the literature. , 2012, The Journal of infection.

[6]  K. Peck,et al.  Osteomyelitis of a long bone due to Fusobacterium nucleatum and Actinomyces meyeri in an immunocompetent adult: A case report and literature review , 2012, BMC Infectious Diseases.

[7]  Kirandeep Gill,et al.  Primary actinomycosis of the foot: a case report and literature review. , 2009, The journal of the American College of Certified Wound Specialists.

[8]  P. Talbot,et al.  Identification of Clinical Isolates ofActinomyces Species by Amplified 16S Ribosomal DNA Restriction Analysis , 2001, Journal of Clinical Microbiology.

[9]  D. Murdoch Gram-Positive Anaerobic Cocci , 1998, Clinical Microbiology Reviews.

[10]  S. Jenkins,et al.  Sclerosing osteomyelitis and Actinomyces naeslundii infection of surrounding tissues. , 1995, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[11]  D. Pang,et al.  Osteomyelitis of the Foot Due to Actinomyces meyeri: A Case Report , 1987, Foot & ankle.

[12]  R. Smego Actinomycosis of the central nervous system. , 1987, Reviews of infectious diseases.

[13]  J. Harrelson,et al.  Primary actinomycosis of an extremity: a case report and review. , 1987, Reviews of infectious diseases.

[14]  H. Larson,et al.  Pathology of the Liver , 1980 .

[15]  John E. Bennett,et al.  Principles and practice of infectious diseases. Vols 1 and 2. , 1979 .

[16]  G. Hodges,et al.  Clindamycin in the treatment of serious anaerobic infections. , 1973, Annals of internal medicine.

[17]  P. Holm Studies on the aetiology of human actinomycosis. , 2009, Acta pathologica et microbiologica Scandinavica. Supplementum.

[18]  P. Holm Studies on the aetiology of human actinomycosis. II. Do the other microbes of actinomycosis possess virulence? , 2009, Acta pathologica et microbiologica Scandinavica.

[19]  P. Holm Studies on the Aetiology of Human Aetinomycosis. I. The " Other Microbes" of Actinomycosis and their Importance. , 1950 .

[20]  R. Klaber Primary Actinomycosis of the Hand , 1933, Proceedings of the Royal Society of Medicine.