Titanium Dioxide, NM-100, NM-101, NM-102, NM-103, NM-104, NM-105: Characterisation and Physico-Chemical Properties

In 2011 the JRC launched a repository for Representative Nanomaterials to support both EU and international research projects, and especially the OECD Working Party on Manufactured Nanomaterials that leads an exploratory programme "Testing a Representative set of Manufactured Nanomaterials", aiming to generate and collect data on characterisation and (eco)toxicological properties to understand relevant end-points as well as the applicability of OECD Test Guidelines for testing nanomaterials. The Repository responds to a need for nanosafety research purposes: availability of nanomaterial from a single production batch to enhance the comparability of results between different research laboratories and projects. The present report presents the physico-chemical characterisation of the titanium dioxide (TiO2) from the JRC repository: NM100, NM-101, NM-102, NM-103, NM-104 and NM-105. NM-105 was selected as principal material for the OECD test programme "Testing a representative set of manufactured nanomaterials". NM-100 is included as a bulk comparator. The results for more than 15 endpoints are described in this report, including physico-chemical properties such as size and size distribution, crystallite size and electron microscopy images. Sample and test item preparation procedures are addressed. The results are based on studies by several European laboratories participating to the NANOGENOTOX Joint Action, and the JRC.. 86291LB-NA-xxxxx-EN-N LB -N A -2 6 6 3 7 EN -N C o m m isio n ’s in -h o u se doi:10.2788/79554 0 ISBN 978-92-79-38188-1 33333838xxxxx-x