Does This Infant Have Pneumonia

Acute lower respiratory tract illness is common among children seen in primary care. We reviewed the accuracy and precision of the clinical examination in detecting pneumonia in children. Although most cases are viral, it is important to identify bacterial pneumonia to provide appropriate therapy. Studies were identified by searching MEDLINE from 1982 to 1995, reviewing reference lists, reviewing a published compendium of studies of the clinical examination, and consulting experts. Observer agreement is good for most signs on the clinical examination. Each study was reviewed by 2 observers and graded for methodologic quality. There is better agreement about signs that can be observed (eg, use of accessory muscles, color, attentiveness; κ, 0.48-0.66) than signs that require auscultation of the chest (eg, adventitious sounds; κ, 0.3). Measurements of the respiratory rate are enhanced by counting for 60 seconds. The best individual finding for ruling out pneumonia is the absence of tachypnea. Chest indrawing, and other signs of increased work of breathing, increases the likelihood of pneumonia. If all clinical signs (respiratory rate, auscultation, and work of breathing) are negative, the chest x-ray findings are unlikely to be positive. Studies are needed to assess the value of clinical findings when they are used together.

[1]  Marsha S. Anderson,et al.  Grunting respirations in infants and children , 1995, Pediatric emergency care.

[2]  M. D. Del Beccaro,et al.  Establishing clinically relevant standards for tachypnea in febrile children younger than 2 years. , 1995, Archives of pediatrics & adolescent medicine.

[3]  Zonghan Zhu,et al.  Respiratory rate and signs in roentgenographically confirmed pneumonia among children in China , 1995, The Pediatric infectious disease journal.

[4]  M. Steinhoff,et al.  Clinical predictors of acute radiological pneumonia and hypoxaemia at high altitude. , 1994, Archives of disease in childhood.

[5]  T. Permutt,et al.  Correcting respiratory rate for the presence of fever. , 1994, Journal of clinical epidemiology.

[6]  S. Redd,et al.  Comparison of the clinical and radiographic diagnosis of paediatric pneumonia. , 1994, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[7]  F. Harrell,et al.  Accuracy of the clinical examination in detecting hypoxemia in infants with respiratory illness. , 1994, The Journal of pediatrics.

[8]  S. Soimakallio,et al.  Comparison of radiological findings and microbial aetiology of childhood pneumonia , 1993, Acta paediatrica.

[9]  S. Gove,et al.  Standardized diagnosis of pneumonia in developing countries. , 1992, The Pediatric infectious disease journal.

[10]  E. Simões,et al.  Respiratory rate: measurement of variability over time and accuracy at different counting periods. , 1991, Archives of disease in childhood.

[11]  P. Bijur,et al.  Is a chest radiograph necessary in the evaluation of every febrile infant less than 8 weeks of age? , 1991, Pediatrics.

[12]  E. Simões,et al.  Respiratory rate and pneumonia in infancy. , 1991, Archives of disease in childhood.

[13]  B. Selwyn The epidemiology of acute respiratory tract infection in young children: comparison of findings from several developing countries. Coordinated Data Group of BOSTID Researchers. , 1990, Reviews of infectious diseases.

[14]  F. Shann,et al.  Clinical findings and severity of acute bronchiolitis , 1990, The Lancet.

[15]  E. Wafula,et al.  The diagnostic value of various features for acute lower respiratory infection among under fives. , 1989, East African medical journal.

[16]  J. Lewtas,et al.  Home air nicotine levels and urinary cotinine excretion in preschool children. , 1989, The American review of respiratory disease.

[17]  R. Turner,et al.  Accuracy of Radiographic Differentiation of Bacterial from Nonbacterial Pneumonia , 1989, Clinical pediatrics.

[18]  D. Isaacs,et al.  Problems in determining the etiology of community-acquired childhood pneumonia. , 1989, The Pediatric infectious disease journal.

[19]  F. Shann CLINICAL SIGNS OF PNEUMONIA IN CHILDREN , 1988, The Lancet.

[20]  C. Hall,et al.  Risk of secondary bacterial infection in infants hospitalized with respiratory syncytial viral infection. , 1988, The Journal of pediatrics.

[21]  G. M. Davis,et al.  Pulmonary and chest wall mechanics in the control of respiration in the newborn. , 1987, Clinics in perinatology.

[22]  J. Hoffman,et al.  Correlation of pulmonary signs and symptoms with chest radiographs in the pediatric age group. , 1986, Annals of emergency medicine.

[23]  S. Kirchner,et al.  Diagnostic imaging in children with acute chest and abdominal disorders. , 1985, Pediatric clinics of North America.

[24]  R A Greenes,et al.  Assessment of Diagnostic Technologies: Methodology for Unbiased Estimation from Samples of Selectively Verified Patients , 1985, Investigative radiology.

[25]  J R Alexander,et al.  Sequential 22-hour profiles of breathing patterns and heart rate in 110 full-term infants during their first 6 months of life. , 1984, Pediatrics.

[26]  P. A. R. Koopman,et al.  Confidence intervals for the ratio of two binomial proportions , 1984 .

[27]  J. Leventhal Clinical Predictors of Pneumonia As a Guide to Ordering Chest Roentgenograms , 1982, Clinical pediatrics.

[28]  R. Ablow,et al.  Radiographic Findings and Etiologic Diagnosis in Ambulatory Childhood Pneumonias , 1981, Clinical pediatrics.

[29]  A. M. Collier,et al.  The etiologic and epidemiologic spectrum of bronchiolitis in pediatric practice. , 1979, The Journal of pediatrics.

[30]  M. Sterman,et al.  Polygraphic Studies of Normal Infants during the First Six Months of Life. I. Heart Rate and Variability as a Function of State , 1976, Pediatric Research.

[31]  K. Connolly,et al.  The Relation of Respiration Rate and Heart Rate to Sleep States in the Human Newborn , 1971, Developmental medicine and child neurology.

[32]  E J Campbell,et al.  Physical signs of diffuse airways obstruction and lung distension , 1969, Thorax.

[33]  A. Iliff,et al.  Pulse rate, respiratory rate, and body temperature of children between two months and eighteen years of age. , 1952, Child development.

[34]  S. Redd,et al.  Clinical signs of pneumonia in children attending a hospital outpatient department in Lesotho. , 1994, Bulletin of the World Health Organization.

[35]  R. Black,et al.  Assessment of respiratory rate and chest indrawing in children with ARI by primary care physicians in Egypt. , 1993, Bulletin of the World Health Organization.

[36]  E. Wang,et al.  Observer agreement for respiratory signs and oximetry in infants hospitalized with lower respiratory infections. , 1992, The American review of respiratory disease.

[37]  K. McConnochie,et al.  Lower respiratory tract illness in the first two years of life: epidemiologic patterns and costs in a suburban pediatric practice. , 1988, American journal of public health.

[38]  L. Swischuk,et al.  Roentgenographic features of common pediatric viral respiratory tract infections. , 1988, American journal of diseases of children.

[39]  P. Gardner,et al.  The radiological findings in respiratory syncytial virus infection in children , 1974, Pediatric radiology.