Klebsiella in faecal flora of renal-transplant patients.

Abstract The incidence and number of Klebsiella in the faecal flora were examined in ten patients who received renal transplants. The faeces were examined while patients were both in and out of hospital during haemodialysis and before and after transplantation, for 2-13 months. The administration of antibiotics to treat infections was associated with a significant increase in the incidence and numbers of Klebsiella in the faecal flora. Patients in hospital did not have a significantly higher incidence or number of Klebsiella in the faeces than outpatients. A wide range of serotypes was present in the faeces, the environment, and in Klebsiella infections and no particular strains predominated in this group of patients. Food was considered to be a likely source of the Klebsiella in the faecal flora. Large numbers of Klebsiella were found in milk shakes mixed with a contaminated mixer. Other foods also contained Klebsiella. The serotypes isolated from a small number of infections had been isolated previously from the patient's faeces in three of five instances. On one other occasion the source of the Klebsiella was considered to be the nasal flora of a nurse.

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