Advanced Mitochondrial Respiration Assay for Evaluation of Mitochondrial Dysfunction in Alzheimer's Disease.

[1]  J. Götz,et al.  Insights into mitochondrial dysfunction: aging, amyloid-β, and tau-A deleterious trio. , 2012, Antioxidants & redox signaling.

[2]  J. Götz,et al.  Mitochondrial dysfunction - the beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid-β toxicity , 2011, Alzheimer's Research & Therapy.

[3]  Lucia Pagani,et al.  Amyloid-Beta Interaction with Mitochondria , 2011, International journal of Alzheimer's disease.

[4]  Jürgen Götz,et al.  Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease , 2011, Nature Reviews Neuroscience.

[5]  Ezzie Hutchinson,et al.  Systems neuroscience: The stress of dieting , 2011, Nature Reviews Neuroscience.

[6]  Jürgen Götz,et al.  Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models , 2010, Cell.

[7]  George Perry,et al.  Alzheimer's disease: diverse aspects of mitochondrial malfunctioning. , 2010, International journal of clinical and experimental pathology.

[8]  F. Müller-Spahn,et al.  Amyloid-beta Leads to Impaired Cellular Respiration, Energy Production and Mitochondrial Electron Chain Complex Activities in Human Neuroblastoma Cells , 2009, Cellular and Molecular Neurobiology.

[9]  M. Fändrich,et al.  Oligomeric and fibrillar species of β-amyloid (Aβ42) both impair mitochondrial function in P301L tau transgenic mice , 2008, Journal of Molecular Medicine.

[10]  J. Götz,et al.  Soluble Beta-Amyloid Leads to Mitochondrial Defects in Amyloid Precursor Protein and Tau Transgenic Mice , 2008, Neurodegenerative Diseases.

[11]  E. Gnaiger Polarographic Oxygen Sensors, the Oxygraph, and High‐Resolution Respirometry to Assess Mitochondrial Function , 2008 .

[12]  P. Reddy,et al.  Mitochondrial dysfunction in aging and Alzheimer's disease: strategies to protect neurons. , 2007, Antioxidants & redox signaling.

[13]  N. Kraut,et al.  Proteomic and functional alterations in brain mitochondria from Tg2576 mice occur before amyloid plaque deposition , 2007, Proteomics.

[14]  J. Götz,et al.  Do axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease? , 2006, Journal of neurochemistry.

[15]  X. Chen,et al.  Mitochondrial Aβ: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease , 2005 .

[16]  R. Ravid,et al.  Proteomic and Functional Analyses Reveal a Mitochondrial Dysfunction in P301L Tau Transgenic Mice* , 2005, Journal of Biological Chemistry.

[17]  J. Götz,et al.  Amyloid-induced neurofibrillary tangle formation in Alzheimer's disease: insight from transgenic mouse and tissue-culture models , 2004, International Journal of Developmental Neuroscience.

[18]  R. Martínez-Murillo,et al.  Intra- and extracellular Abeta and PHF in clinically evaluated cases of Alzheimer's disease. , 2004, Histology and histopathology.

[19]  J. Quinn,et al.  Gene expression profiles of transcripts in amyloid precursor protein transgenic mice: up-regulation of mitochondrial metabolism and apoptotic genes is an early cellular change in Alzheimer's disease. , 2004, Human molecular genetics.

[20]  T. Bayer,et al.  Time sequence of maturation of dystrophic neurites associated with Aβ deposits in APP/PS1 transgenic mice , 2003, Experimental Neurology.

[21]  J. Kemp,et al.  PS2APP Transgenic Mice, Coexpressing hPS2mut and hAPPswe, Show Age-Related Cognitive Deficits Associated with Discrete Brain Amyloid Deposition and Inflammation , 2003, The Journal of Neuroscience.

[22]  Hsueh‐Meei Huang,et al.  Oxidative processes in the brain and non-neuronal tissues as biomarkers of Alzheimer's disease. , 2002, Frontiers in bioscience : a journal and virtual library.

[23]  R. Nitsch,et al.  Formation of Neurofibrillary Tangles in P301L Tau Transgenic Mice Induced by Aβ42 Fibrils , 2001, Science.

[24]  I. Scheffler,et al.  A century of mitochondrial research: achievements and perspectives. , 2001, Mitochondrion.

[25]  R. Nitsch,et al.  Tau Filament Formation in Transgenic Mice Expressing P301L Tau* , 2001, The Journal of Biological Chemistry.

[26]  L. Mucke,et al.  Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein , 1995, Nature.

[27]  N. Schonrock,et al.  Is tau aggregation toxic or protective: a sensible question in the absence of sensitive methods? , 2008, Journal of Alzheimer's disease : JAD.

[28]  Xiaomin Song,et al.  Amyloid- (cid:1) and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer’s disease mice , 2009 .