Advanced Mitochondrial Respiration Assay for Evaluation of Mitochondrial Dysfunction in Alzheimer's Disease.
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[1] J. Götz,et al. Insights into mitochondrial dysfunction: aging, amyloid-β, and tau-A deleterious trio. , 2012, Antioxidants & redox signaling.
[2] J. Götz,et al. Mitochondrial dysfunction - the beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid-β toxicity , 2011, Alzheimer's Research & Therapy.
[3] Lucia Pagani,et al. Amyloid-Beta Interaction with Mitochondria , 2011, International journal of Alzheimer's disease.
[4] Jürgen Götz,et al. Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease , 2011, Nature Reviews Neuroscience.
[5] Ezzie Hutchinson,et al. Systems neuroscience: The stress of dieting , 2011, Nature Reviews Neuroscience.
[6] Jürgen Götz,et al. Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models , 2010, Cell.
[7] George Perry,et al. Alzheimer's disease: diverse aspects of mitochondrial malfunctioning. , 2010, International journal of clinical and experimental pathology.
[8] F. Müller-Spahn,et al. Amyloid-beta Leads to Impaired Cellular Respiration, Energy Production and Mitochondrial Electron Chain Complex Activities in Human Neuroblastoma Cells , 2009, Cellular and Molecular Neurobiology.
[9] M. Fändrich,et al. Oligomeric and fibrillar species of β-amyloid (Aβ42) both impair mitochondrial function in P301L tau transgenic mice , 2008, Journal of Molecular Medicine.
[10] J. Götz,et al. Soluble Beta-Amyloid Leads to Mitochondrial Defects in Amyloid Precursor Protein and Tau Transgenic Mice , 2008, Neurodegenerative Diseases.
[11] E. Gnaiger. Polarographic Oxygen Sensors, the Oxygraph, and High‐Resolution Respirometry to Assess Mitochondrial Function , 2008 .
[12] P. Reddy,et al. Mitochondrial dysfunction in aging and Alzheimer's disease: strategies to protect neurons. , 2007, Antioxidants & redox signaling.
[13] N. Kraut,et al. Proteomic and functional alterations in brain mitochondria from Tg2576 mice occur before amyloid plaque deposition , 2007, Proteomics.
[14] J. Götz,et al. Do axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease? , 2006, Journal of neurochemistry.
[15] X. Chen,et al. Mitochondrial Aβ: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease , 2005 .
[16] R. Ravid,et al. Proteomic and Functional Analyses Reveal a Mitochondrial Dysfunction in P301L Tau Transgenic Mice* , 2005, Journal of Biological Chemistry.
[17] J. Götz,et al. Amyloid-induced neurofibrillary tangle formation in Alzheimer's disease: insight from transgenic mouse and tissue-culture models , 2004, International Journal of Developmental Neuroscience.
[18] R. Martínez-Murillo,et al. Intra- and extracellular Abeta and PHF in clinically evaluated cases of Alzheimer's disease. , 2004, Histology and histopathology.
[19] J. Quinn,et al. Gene expression profiles of transcripts in amyloid precursor protein transgenic mice: up-regulation of mitochondrial metabolism and apoptotic genes is an early cellular change in Alzheimer's disease. , 2004, Human molecular genetics.
[20] T. Bayer,et al. Time sequence of maturation of dystrophic neurites associated with Aβ deposits in APP/PS1 transgenic mice , 2003, Experimental Neurology.
[21] J. Kemp,et al. PS2APP Transgenic Mice, Coexpressing hPS2mut and hAPPswe, Show Age-Related Cognitive Deficits Associated with Discrete Brain Amyloid Deposition and Inflammation , 2003, The Journal of Neuroscience.
[22] Hsueh‐Meei Huang,et al. Oxidative processes in the brain and non-neuronal tissues as biomarkers of Alzheimer's disease. , 2002, Frontiers in bioscience : a journal and virtual library.
[23] R. Nitsch,et al. Formation of Neurofibrillary Tangles in P301L Tau Transgenic Mice Induced by Aβ42 Fibrils , 2001, Science.
[24] I. Scheffler,et al. A century of mitochondrial research: achievements and perspectives. , 2001, Mitochondrion.
[25] R. Nitsch,et al. Tau Filament Formation in Transgenic Mice Expressing P301L Tau* , 2001, The Journal of Biological Chemistry.
[26] L. Mucke,et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein , 1995, Nature.
[27] N. Schonrock,et al. Is tau aggregation toxic or protective: a sensible question in the absence of sensitive methods? , 2008, Journal of Alzheimer's disease : JAD.
[28] Xiaomin Song,et al. Amyloid- (cid:1) and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer’s disease mice , 2009 .