Treating seizures in Creutzfeldt–Jakob disease# The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters

Seizures are known to occur in Creutzfeldt – Jakob disease (CJD). In the setting of a rapidly progressive condition with no effective therapy, determining appropriate treatment for seizures can be dif fi cult if clinical morbidity is not obvious yet the electroencephalogram (EEG) demonstrates a worrisome pattern such as status epilepticus. Herein, we present the case of a 39-year-old man with CJD and electrographic seizures, discuss how this case challengesconventionalde fi nitionsofseizures,anddiscussarationalapproachtowardtreatment.Coincidentally, our case is the fi rst report of CJD in a patient with Stickler syndrome. © 2014 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license

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