Nonlinear model predictive control of joint ankle by electrical stimulation for drop foot correction

In this paper we investigate the use of optimal control techniques to improve Functional Electrical Stimulation (FES) for drop foot correction on hemiplegic patients. A model of the foot and the tibialis anterior muscle, the contraction of which is controlled by electrical stimulation has been established and is used in the optimal control problem. The novelty in this work is the use of the ankle accelerations and shank orientations (so-called external states) in the model, which have been measured on hemiplegic patients in a previous experiment using Inertial Measurement Units (IMUs). The optimal control problem minimizes the square of muscle excitations which serves the overall goal of reducing energy consumption in the muscle. In a first step, an offline optimal control problem is solved for test purposes and shows the efficiency of the FES optimal control for drop foot correction. In a second step, a Nonlinear Model Predictive Control (NMPC) problem - or online optimal control problem, is solved in a simulated environment. While the ulitmate goal is to use NMPC on the real system, i.e. directly on the patient, this test in simulation was meant to show the feasibility of NMPC for online drop foot correction. In the optimization problem, a set of fixed constraints of foot orientation was applied. Then, an original adaptive constraint taking into account the current ankle height, was introduced and tested. Comparisons between results under fixed and adaptive constraints highlight the advantage of the adaptive constraints in terms of energy consumption, where its quadratic sum of controls, obtained by NMPC, was three times lower than with the fixed constraint. This feasibility study was a first step in application of NMPC on real hemiplegic patients for online FES-based drop foot correction. The adaptive constraints method presents a new and efficient approach in terms of muscular energy consumption minimization.

[1]  H. Bock,et al.  A Multiple Shooting Algorithm for Direct Solution of Optimal Control Problems , 1984 .

[2]  G. Lyons,et al.  Evaluation of a Drop Foot Stimulator FES Intensity Envelope Matched to Tibialis Anterior Muscle Activity during Walking , 2001 .

[3]  W. Marsden I and J , 2012 .

[4]  T. Sinkjaer,et al.  A review of portable FES-based neural orthoses for the correction of drop foot , 2002, IEEE Transactions on Neural Systems and Rehabilitation Engineering.

[5]  Johannes P. Schlöder,et al.  An efficient multiple shooting based reduced SQP strategy for large-scale dynamic process optimization. Part 1: theoretical aspects , 2003, Comput. Chem. Eng..

[6]  G. Lyons,et al.  The development of a potential optimized stimulation intensity envelope for drop foot applications , 2003, IEEE Transactions on Neural Systems and Rehabilitation Engineering.

[7]  P H Veltink,et al.  Three dimensional inertial sensing of foot movements for automatic tuning of a two-channel implantable drop-foot stimulator. , 2003, Medical engineering & physics.

[8]  J P Paul,et al.  Hybrid FES orthosis incorporating closed loop control and sensory feedback. , 1988, Journal of biomedical engineering.

[9]  Thomas Sinkjær,et al.  Control of Movement for the Physically Disabled: Control for Rehabilitation Technology , 2000 .

[10]  D Kotiadis,et al.  Inertial Gait Phase Detection for control of a drop foot stimulator Inertial sensing for gait phase detection. , 2010, Medical engineering & physics.

[11]  Philippe Poignet,et al.  Optimal Functional Electrical Stimulation patterns synthesis for knee joint control , 2008, 2008 IEEE/RSJ International Conference on Intelligent Robots and Systems.

[12]  Lei Wang,et al.  Analysis of filtering methods for 3D acceleration signals in body sensor network , 2011, International Symposium on Bioelectronics and Bioinformations 2011.

[13]  P. Poignet,et al.  Identification and validation of FES physiological musculoskeletal model in paraplegic subjects , 2009, 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[14]  H.B.K. Boom,et al.  Automatic stance-swing phase detection from accelerometer data for peroneal nerve stimulation , 1990, IEEE Transactions on Biomedical Engineering.

[15]  Peter H. Veltink,et al.  Measuring orientation of human body segments using miniature gyroscopes and accelerometers , 2005, Medical and Biological Engineering and Computing.

[16]  G M Lyons,et al.  A system for the delivery of programmable, adaptive stimulation intensity envelopes for drop foot correction applications. , 2006, Medical engineering & physics.

[17]  Rodolphe Héliot,et al.  Online CPG-Based Gait Monitoring and Optimal Control of the Ankle Joint for Assisted Walking in Hemiplegic Subjects , 2013 .

[18]  Jin-Shin Lai,et al.  Neural network and fuzzy control in FES-assisted locomotion for the hemiplegic , 2004, Journal of medical engineering & technology.

[19]  Peter H. Veltink,et al.  Control of triceps surae stimulation based on shank orientation using a uniaxial gyroscope during gait , 2009, Medical & Biological Engineering & Computing.

[20]  Moritz Diehl,et al.  Real-Time Optimization for Large Scale Nonlinear Processes , 2001 .

[21]  J. Winters Hill-Based Muscle Models: A Systems Engineering Perspective , 1990 .

[22]  Eric Loth,et al.  A portable powered ankle-foot orthosis for rehabilitation. , 2011, Journal of rehabilitation research and development.

[23]  R. Riener,et al.  Identification of passive elastic joint moments in the lower extremities. , 1999, Journal of biomechanics.

[24]  Liberson Wt,et al.  Functional electrotherapy: stimulation of the peroneal nerve synchronized with the swing phase of the gait of hemiplegic patients. , 1961, Archives of physical medicine and rehabilitation.

[25]  Yu-Luen Chen,et al.  Alternative control in FES-assisted locomotion , 2003, IEEE EMBS Asian-Pacific Conference on Biomedical Engineering, 2003..

[26]  David Q. Mayne,et al.  Constrained model predictive control: Stability and optimality , 2000, Autom..