Preclinical evidence that MNK/eIF4E inhibition by cercosporamide enhances the response to antiangiogenic TKI and mTOR inhibitor in renal cell carcinoma.
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[1] C. Wood,et al. Temsirolimus versus Pazopanib (TemPa) in Patients with Advanced Clear-cell Renal Cell Carcinoma and Poor-risk Features: A Randomized Phase II Trial. , 2020, European urology oncology.
[2] N. Agarwal,et al. First-line Treatment of Metastatic Renal Cell Carcinoma: A Systematic Review and Network Meta-analysis. , 2019, European urology oncology.
[3] C. Porta,et al. Renal cell carcinoma treatment after first-line combinations. , 2019, The Lancet. Oncology.
[4] M. Milik,et al. Mitogen-activated Protein Kinase (MAPK) Interacting Kinases 1 and 2 (MNK1 and MNK2) as Targets for Cancer Therapy: Recent Progress in the Development of MNK Inhibitors. , 2017, Current medicinal chemistry.
[5] Charles Swanton,et al. Renal cell carcinoma , 2017, Nature Reviews Disease Primers.
[6] C. Porta,et al. Choosing the right cell line for renal cell cancer research , 2016, Molecular Cancer.
[7] Sien Guo,et al. Inhibition of eukaryotic initiation factor 4E phosphorylation by cercosporamide selectively suppresses angiogenesis, growth and survival of human hepatocellular carcinoma. , 2016, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[8] J. Seebacher,et al. Inhibition of MNK pathways enhances cancer cell response to chemotherapy with temozolomide and targeted radionuclide therapy. , 2016, Cellular signalling.
[9] Sen Chen,et al. Niclosamide suppresses renal cell carcinoma by inhibiting Wnt/β-catenin and inducing mitochondrial dysfunctions , 2016, SpringerPlus.
[10] Sen Chen,et al. Mefloquine effectively targets gastric cancer cells through phosphatase-dependent inhibition of PI3K/Akt/mTOR signaling pathway. , 2016, Biochemical and biophysical research communications.
[11] J. Larkin,et al. Preclinical Evidence That Trametinib Enhances the Response to Antiangiogenic Tyrosine Kinase Inhibitors in Renal Cell Carcinoma , 2015, Molecular Cancer Therapeutics.
[12] A. Reynolds,et al. Anti-angiogenic therapy for cancer: current progress, unresolved questions and future directions , 2014, Angiogenesis.
[13] J. Reeves,et al. Pazopanib versus sunitinib in metastatic renal-cell carcinoma. , 2013, The New England journal of medicine.
[14] P. Iversen,et al. Inhibition of Mnk kinase activity by cercosporamide and suppressive effects on acute myeloid leukemia precursors. , 2013, Blood.
[15] J. Larkin,et al. Current and future systemic treatments for renal cell carcinoma. , 2013, Seminars in cancer biology.
[16] C. Proud,et al. Targeting Mnks for Cancer Therapy , 2012, Oncotarget.
[17] N. Sonenberg,et al. Therapeutic inhibition of MAP kinase interacting kinase blocks eukaryotic initiation factor 4E phosphorylation and suppresses outgrowth of experimental lung metastases. , 2011, Cancer research.
[18] T. Mak,et al. Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development , 2010, Proceedings of the National Academy of Sciences.
[19] H. Kleinman,et al. In vitro angiogenesis: endothelial cell tube formation on gelled basement membrane extract , 2010, Nature Protocols.
[20] T. Chou. Drug combination studies and their synergy quantification using the Chou-Talalay method. , 2010, Cancer research.
[21] S. Lowe,et al. Dissecting eIF4E action in tumorigenesis. , 2007, Genes & development.
[22] O. Larsson,et al. Eukaryotic translation initiation factor 4E induced progression of primary human mammary epithelial cells along the cancer pathway is associated with targeted translational deregulation of oncogenic drivers and inhibitors. , 2007, Cancer research.
[23] S. Nagata,et al. Mnk2 and Mnk1 Are Essential for Constitutive and Inducible Phosphorylation of Eukaryotic Initiation Factor 4E but Not for Cell Growth or Development , 2004, Molecular and Cellular Biology.
[24] N. Sonenberg,et al. Eukaryotic translation initiation factors and regulators. , 2003, Current opinion in structural biology.
[25] W. Thoenes,et al. Histopathology and classification of renal cell tumors (adenomas, oncocytomas and carcinomas). The basic cytological and histopathological elements and their use for diagnostics. , 1986, Pathology, research and practice.
[26] L. Platanias,et al. Dual targeting of eIF4E by blocking MNK and mTOR pathways in leukemia , 2017, Cytokine.
[27] A. Gingras,et al. eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation. , 1999, Annual review of biochemistry.