Understanding Biochemical Reactions: SABIO-RK: Database for Reaction Kinetics

The understanding of cellular behavior and complex biochemical processes requires detailed qualitative and quantitative information about single biochemical reactions. Hence for the simulation und modeling of biochemical reactions and complex networks reliable kinetic data for the individual reaction steps are essential. Kinetic laws describing the dynamics of the reactions with their respective parameters determined under certain experimental conditions are mainly found in the literature and described in many different formats and vocabularies. SABIO-RK [1, 2] is a curated, web-accessible database which integrates, standardizes and annotates these data in a structured format. A general overview about the data flow in the SABIO-RK project is represented in figure 1.