Reformatsky reactions with N-arylpyrrolidine-2-thiones: synthesis of tricyclic analogues of quinolone antibacterial agents

[1]  N. Osheroff,et al.  Type II topoisomerases as targets for quinolone antibacterials: turning Dr. Jekyll into Mr. Hyde. , 2001, Current pharmaceutical design.

[2]  M. Fujita,et al.  Stereoselective synthesis of diastereomeric atropisomeric lactam with various ring sizes and their structural characterization , 2000 .

[3]  P. Appelbaum,et al.  The fluoroquinolone antibacterials: past, present and future perspectives. , 2000, International journal of antimicrobial agents.

[4]  J. Stables,et al.  Enaminones-versatile therapeutic pharmacophores. Further advances. , 2000, Current medicinal chemistry.

[5]  Hasegawa,et al.  Synthesis of optically active 5-substituted-2-pyrrolidinone derivatives having atropisomeric structure and 3,5-cis-selective reaction of their enolates with electrophiles , 2000, The Journal of organic chemistry.

[6]  S. Pelly,et al.  Enaminones: versatile intermediates for natural product synthesis , 1999 .

[7]  C. Pak,et al.  Reaction of thioamides with zinc enolate: Synthesis of vinylogous carbamates , 1999 .

[8]  K. Lee,et al.  Recent advances in the discovery and development of quinolones and analogs as antitumor agents. , 1999, Current medicinal chemistry.

[9]  C. B. Koning,et al.  A versatile synthesis of tricyclic analogues of quinolone antibacterial agents: Use of a novel reformatsky reaction , 1996 .

[10]  T. Gootz,et al.  Fluoroquinolone antibacterials: SAR, mechanism of action, resistance, and clinical aspects , 1996, Medicinal research reviews.

[11]  T. Kinoshita,et al.  A novel synthesis of the pyrazolo[1,5-a]quinoline ring system. New N1-C2 bridged DNA gyrase inhibitors via a novel tandem 1,4-conjugate addition-Michael [3+2] annulation process , 1996 .

[12]  K. Scott,et al.  Anticonvulsant enaminones: with emphasis on methyl 4-[(p-chlorophenyl)amino]-6-methyl-2-oxocyclohex-3-en-1-oate (ADD 196022) , 1994 .

[13]  Guncheol Kim,et al.  A synthesis of (±)-supinidine via an intramolecular carbenoid-thioimide coupling reaction , 1994 .

[14]  L. Bhat,et al.  Reformatsky Reaction on Thiocarbonyl Compounds : New C-C Bond Forming Reaction , 1993 .

[15]  G. Schulte,et al.  The total synthesis of indolizomycin , 1993 .

[16]  S. Rádl,et al.  Recent Advances in the Synthesis of Antibacterial Quinolones , 1993 .

[17]  G. Crumplin The 4-Quinolones: Anti Bacterial Agents in Vitro , 1990, Springer Series in Applied Biology.

[18]  D. Boger,et al.  Total synthesis and evaluation of (.+-.)-N-(tert-butoxycarbonyl)-CBI, (.+-.)-CBI-CDPI1, and (.+-.)-CBI-CDPI2: CC-1065 functional agents incorporating the equivalent 1,2,9,9a-tetrahydrocyclopropa[1,2-c]benz[1,2-e]indol-4-one (CBI) left-hand subunit , 1989 .

[19]  J. Michael,et al.  Syntheses of alkyl (E)-(1-aryl-2-pyrrolidinylidene)acetates , 1988 .

[20]  D. Chu,et al.  Short syntheses of 1,2,3,5‐tetrahydro‐5‐oxopyrrolo‐[1,2‐a]quinoline‐4‐carboxylic acid and 1,2,3,4‐tetrahydro‐6H‐6‐oxopyrido[1,2‐a]quinoline‐5‐carboxylic acid derivatives , 1987 .

[21]  M. V. Sargent,et al.  Boron trichloride as a selective demethylating agent for hindered ethers: a synthesis of the phytoalexins α- and β-pyrufuran, a synthesis of tri-O-methylleprolomin and its demethylation , 1984 .

[22]  S. Raucher,et al.  Ultrasound in heterogeneous organic reactions. Improved procedure for the synthesis of thioamides , 1981 .

[23]  G. Coppola,et al.  Novel heterocycles. 6. The condensation of ethyl o‐fluorobenzoyl acetate with cyclic imino ethers , 1980 .

[24]  M. Roth,et al.  Sulfidkontraktion via alkylative Kupplung: Eine methode zur darstellung von β‐dicarbonylderivaten. Über synthetische methoden, 1. Mitteilung , 1971 .

[25]  M. S. Manhas,et al.  Cyclization of .omega.-halo amides to lactams , 1967 .

[26]  J. S. Buck,et al.  Some 9-Amino-3-nitroacridine Derivatives , 1957 .

[27]  R. Gould,et al.  The Synthesis of Certain Substituted Quinolines and 5,6-Benzoquinolines , 1939 .