A stochastic carcinogenesis model incorporating genomic instability fitted to colon cancer data.

[1]  岩崎 民子.  SOURCES AND EFFECTS OF IONIZING RADIATION : United Nations Scientific Committee on the Effects of Atomic Radiation UNSCEAR 2000 Report to the General Assembly, with Scientific Annexes , 2002 .

[2]  C. Muirhead,et al.  Modelling lung tumour risk in radon-exposed uranium miners using generalizations of the two-mutation model of Moolgavkar, Venzon and Knudson , 2002, International journal of radiation biology.

[3]  C. Whitehouse,et al.  No Evidence for Chromosomal Instability in Radiation Workers with In Vivo Exposure to Plutonium , 2001, Radiation research.

[4]  Megu Ohtaki,et al.  A Mathematical Model of Radiation Carcinogenesis with Induction of Genomic Instability and Cell Death , 2001, Radiation research.

[5]  W F Heidenreich,et al.  Analysis of a Historical Cohort of Chinese Tin Miners with Arsenic, Radon, Cigarette Smoke, and Pipe Smoke Exposures Using the Biologically Based Two-Stage Clonal Expansion Model , 2001, Radiation research.

[6]  L. Loeb,et al.  A mutator phenotype in cancer. , 2001, Cancer research.

[7]  J D Harrison,et al.  Lack of Detectable Transmissible Chromosomal Instability after In Vivo or In Vitro Exposure of Mouse Bone Marrow Cells to 224Ra Alpha Particles , 2001, Radiation research.

[8]  E. Wright,et al.  In vivo chromosomal instability and transmissible aberrations in the progeny of haemopoietic stem cells induced by high- and low-LET radiations , 2001, International journal of radiation biology.

[9]  W. Heidenreich,et al.  Analysis of lung tumour risk in radon-exposed rats: an intercomparison of multi-step modelling , 2000, Radiation and environmental biophysics.

[10]  K. Baverstock.  Radiation-induced genomic instability: a paradigm-breaking phenomenon and its relevance to environmentally induced cancer. , 2000, Mutation research.

[11]  N. Petrelli,et al.  The onset and extent of genomic instability in sporadic colorectal tumor progression. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[12]  E. Luebeck,et al.  Biologically based analysis of the data for the Colorado uranium miners cohort: age, dose and dose-rate effects. , 1999, Radiation research.

[13]  H P Leenhouts,et al.  Radon-induced lung cancer in smokers and non-smokers: risk implications using a two-mutation carcinogenesis model , 1999, Radiation and environmental biophysics.

[14]  F. T. Cross,et al.  Two-step model for the risk of fatal and incidental lung tumors in rats exposed to radon. , 1999, Radiation research.

[15]  Anthony C. Davison,et al.  Bootstrap Methods and Their Application , 1998 .

[16]  E. Luebeck,et al.  Analysis of the incidence of solid cancer among atomic bomb survivors using a two-stage model of carcinogenesis. , 1997, Radiation research.

[17]  W F Heidenreich,et al.  Some Properties of the Hazard Function of the Two‐Mutation Clonal Expansion Model , 1997, Risk analysis : an official publication of the Society for Risk Analysis.

[18]  D A Pierce,et al.  Studies of the mortality of atomic bomb survivors. Report 12, Part I. Cancer: 1950-1990. , 1996, Radiation research.

[19]  C. Muirhead,et al.  Modelling lymphocytic leukaemia incidence in England and Wales using generalizations of the two-mutation model of carcinogenesis of Moolgavkar, Venzon and Knudson. , 1996, Statistics in medicine.

[20]  M. Little.  Generalisations of the two-mutation and classical multi-stage models of carcinogenesis fitted to the Japanese atomic bomb survivor data , 1996 .

[21]  F. T. Cross,et al.  Two-stage model of radon-induced malignant lung tumors in rats: effects of cell killing. , 1996, Radiation research.

[22]  M. Little,et al.  Are two mutations sufficient to cause cancer? Some generalizations of the two-mutation model of carcinogenesis of Moolgavkar, Venzon, and Knudson, and of the multistage model of Armitage and Doll. , 1995, Biometrics.

[23]  D. T. Goodhead,et al.  α-particle-induced chromosomal instability in human bone marrow cells , 1994, The Lancet.

[24]  D. Preston,et al.  Cancer incidence in atomic bomb survivors. Part II: Solid tumors, 1958-1987. , 1994, Radiation research.

[25]  D Krewski,et al.  Radon, Cigarette Smoke, and Lung Cancer: A Re‐analysis of the Colorado Plateau Uranium Miners' Data , 1993, Epidemiology.

[26]  P. McCullagh,et al.  Generalized Linear Models , 1992 .

[27]  E G Luebeck,et al.  Multistage carcinogenesis: population-based model for colon cancer. , 1992, Journal of the National Cancer Institute.

[28]  D. T. Goodhead,et al.  Transmission of chromosomal instability after plutonium α-particle irradiation , 1992, Nature.

[29]  L. Loeb,et al.  Mutator phenotype may be required for multistage carcinogenesis. , 1991, Cancer research.

[30]  M. Little,et al.  Time variations in radiation-induced relative risk and implications for population cancer risks , 1991 .

[31]  B. Vogelstein,et al.  A genetic model for colorectal tumorigenesis , 1990, Cell.

[32]  S H Moolgavkar,et al.  Two-event model for carcinogenesis: biological, mathematical, and statistical considerations. , 1990, Risk analysis : an official publication of the Society for Risk Analysis.

[33]  W. Press,et al.  Numerical Recipes: FORTRAN , 1990 .

[34]  William H. Press,et al.  Numerical recipes in C. The art of scientific computing , 1987 .

[35]  P. McCullagh,et al.  Generalized Linear Models , 1984 .

[36]  J. Little,et al.  Relationship between x-ray exposure and malignant transformation in C3H 10T1/2 cells. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[37]  S. Moolgavkar,et al.  Two-event models for carcinogenesis: incidence curves for childhood and adult tumors☆ , 1979 .

[38]  P. Nowell.  The clonal evolution of tumor cell populations. , 1976, Science.

[39]  A. Knudson.  Mutation and cancer: statistical study of retinoblastoma. , 1971, Proceedings of the National Academy of Sciences of the United States of America.

[40]  R. Doll.  The Age Distribution of Cancer: Implications for Models of Carcinogenesis , 1971 .

[41]  P. Armitage,et al.  A Two-stage Theory of Carcinogenesis in Relation to the Age Distribution of Human Cancer , 1957, British Journal of Cancer.

[42]  P. Armitage,et al.  The Age Distribution of Cancer and a Multi-stage Theory of Carcinogenesis , 1954, British Journal of Cancer.

[43]  Ian Tomlinson,et al.  Selection, the mutation rate and cancer: Ensuring that the tail does not wag the dog , 1999, Nature medicine.

[44]  M. Kadhim,et al.  Radiation-induced chromosomal instability in human fibroblasts: temporal effects and the influence of radiation quality. , 1998, International journal of radiation biology.

[45]  A. Balmain,et al.  Stochastic modelling of tumorigenesis in p53 deficient mice. , 1998, British Journal of Cancer.

[46]  F. T. Cross,et al.  A two-mutation model for radon-induced lung tumors in rats. , 1990, Radiation research.

[47]  William H. Press,et al.  Book-Review - Numerical Recipes in Pascal - the Art of Scientific Computing , 1989 .