A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells

[1]  H. Varmus,et al.  Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[2]  J Erikson,et al.  Transcriptional activation of the translocated c-myc oncogene in burkitt lymphoma. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[3]  C. Croce,et al.  Transcriptionally active c-myc oncogene is contained within NIARD, a DNA sequence associated with chromosome translocations in B-cell neoplasia. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[4]  L. Hood,et al.  Mouse c-myc oncogene is located on chromosome 15 and translocated to chromosome 12 in plasmacytomas. , 1982, Science.

[5]  J. Stephenson,et al.  A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia , 1982, Nature.

[6]  Kenji Shimizu,et al.  Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change , 1982, Nature.

[7]  D. Givol,et al.  Activation of a cellular oncogene by DNA rearrangement: possible involvement of an IS-like element , 1982, Nature.

[8]  M. Barbacid,et al.  Oncogenes in solid human tumours , 1982, Nature.

[9]  C. Croce,et al.  Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[10]  P. Leder,et al.  Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[11]  M. Cole,et al.  Novel myc oncogene RNA from abortive immunoglobulin-gene recombination in mouse plasmacytomas , 1982, Cell.

[12]  Eugenio Santos,et al.  A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene , 1982, Nature.

[13]  Cori Bargmann,et al.  Mechanism of activation of a human oncogene , 1982, Nature.

[14]  Harold E. Varmus,et al.  Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome , 1982, Cell.

[15]  E. Scolnick,et al.  Mouse cells contain two distinct ras gene mRNA species that can be translated into a p21 onc protein , 1982, Molecular and cellular biology.

[16]  T. Ryder,et al.  Nucleotide sequence of the oncogene encoding the p21 transforming protein of Kirsten murine sarcoma virus. , 1982, Science.

[17]  R. Gallo,et al.  onc gene amplification in promyelocytic leukaemia cell line HL-60 and primary leukaemic cells of the same patient , 1982, Nature.

[18]  G. Cooper,et al.  Cellular transforming genes. , 1982, Science.

[19]  M. Groudine,et al.  Amplification of endogenous myc-related DNA sequences in a human myeloid leukaemia cell line , 1982, Nature.

[20]  E. Scolnick,et al.  Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family , 1982, Journal of virology.

[21]  D. Lowy,et al.  Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus , 1982, Nature.

[22]  R. Weinberg,et al.  Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene , 1982, Nature.

[23]  C. Der,et al.  Transforming genes of human bladder and lung carcinoma cell lines are homologous to the ras genes of Harvey and Kirsten sarcoma viruses. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[24]  H. Varmus.  Form and function of retroviral proviruses. , 1982, Science.

[25]  D. George,et al.  Amplified DNA sequences in Y1 mouse adrenal tumor cells: association with double minutes and localization to a homogeneously staining chromosomal region. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[26]  P. Barker.  Double minutes in human tumor cells. , 1982, Cancer genetics and cytogenetics.

[27]  H. Varmus,et al.  Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas , 1982, Nature.

[28]  J. Cowell,et al.  Double minutes and homogeneously staining regions: gene amplification in mammalian cells. , 1982, Annual review of genetics.

[29]  R. Weinberg.  Oncogenes of spontaneous and chemically induced tumors. , 1982, Advances in cancer research.

[30]  R. A. Swift,et al.  Specific integration of REV proviruses in avian bursal lymphomas , 1981, Nature.

[31]  M. Gonda,et al.  The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes , 1981, Nature.

[32]  A. Varshavsky.  Phorbol ester dramatically increases incidence of methotrexate-resistant mouse cells: Possible mechanisms and relevance to tumor promotion , 1981, Cell.

[33]  P. Wall,et al.  In pursuit of a self-conscious science , 1981, Nature.

[34]  M. Gonda,et al.  Analysis of two divergent rat genomic clones homologous to the transforming gene of Harvey murine sarcoma virus. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[35]  W. S. Hayward,et al.  Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis , 1981, Nature.

[36]  D. George,et al.  Cloning of DNA from double minutes of Y1 mouse adrenocortical tumor cells: Evidence for gene amplification , 1981, Cell.

[37]  U. Francke,et al.  Homogeneously staining chromosome regions and double minutes in a mouse adrenocortical tumor cell line. , 1980, Cytogenetics and cell genetics.

[38]  I. Pastan,et al.  Localization of the src gene product of the Harvey strain of MSV to plasma membrane of transformed cells by electron microscopic immunocytochemistry , 1980, Cell.

[39]  R. Schimke,et al.  Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[40]  R T Schimke,et al.  Gene amplification and drug resistance in cultured murine cells. , 1978, Science.

[41]  L. Chasin,et al.  Amplified dihydrofolate reductase genes are localized to a homogeneously staining region of a single chromosome in a methotrexate-resistant Chinese hamster ovary cell line. , 1978, Proceedings of the National Academy of Sciences of the United States of America.