Helical α-Synuclein Forms Highly Conductive Ion Channels†
暂无分享,去创建一个
Stanislav D. Zakharov | William A. Cramer | John D. Hulleman | Jean-Christophe Rochet | S. Zakharov | J. Rochet | Y. Antonenko | J. Hulleman | W. Cramer | Elena A. Dutseva | Yuri N. Antonenko | E. Dutseva
[1] P. Lansbury,et al. Vesicle permeabilization by protofibrillar alpha-synuclein is sensitive to Parkinson's disease-linked mutations and occurs by a pore-like mechanism. , 2002, Biochemistry.
[2] J. Korlach,et al. Characterization of lipid bilayer phases by confocal microscopy and fluorescence correlation spectroscopy. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[3] R. Perrin,et al. Interaction of human alpha-Synuclein and Parkinson's disease variants with phospholipids. Structural analysis using site-directed mutagenesis. , 2000, The Journal of biological chemistry.
[4] Jean-Christophe Rochet,et al. Interactions among alpha-synuclein, dopamine, and biomembranes: some clues for understanding neurodegeneration in Parkinson's disease. , 2004, Journal of molecular neuroscience : MN.
[5] Mark R Cookson,et al. The biochemistry of Parkinson's disease. , 2005, Annual review of biochemistry.
[6] C. Hoogland,et al. In The Proteomics Protocols Handbook , 2005 .
[7] A. Harris,et al. Horizontal 'solvent-free' lipid bimolecular membranes with two-sided access can be formed and facilitate ion channel reconstitution. , 1995, Biochimica et biophysica acta.
[8] R. L. Baldwin,et al. Helix propagation and N‐cap propensities of the amino acids measured in alanine‐based peptides in 40 volume percent trifluoroethanol , 1996, Protein science : a publication of the Protein Society.
[9] Y. Shai,et al. Mechanisms for the modulation of membrane bilayer properties by amphipathic helical peptides , 1995, Biopolymers.
[10] S. Zakharov,et al. Lipid Dependence of the Channel Properties of a Colicin E1-Lipid Toroidal Pore* , 2006, Journal of Biological Chemistry.
[11] D. O. Rudin,et al. Reconstitution of Cell Membrane Structure in vitro and its Transformation into an Excitable System , 1962, Nature.
[12] L. Mayer,et al. Vesicles of variable sizes produced by a rapid extrusion procedure. , 1986, Biochimica et biophysica acta.
[13] J. Trojanowski,et al. Synucleins Are Developmentally Expressed, and α-Synuclein Regulates the Size of the Presynaptic Vesicular Pool in Primary Hippocampal Neurons , 2000, The Journal of Neuroscience.
[14] P. Lansbury,et al. Annular alpha-synuclein protofibrils are produced when spherical protofibrils are incubated in solution or bound to brain-derived membranes. , 2002, Biochemistry.
[15] Belinda Wilson,et al. Aggregated α‐synuclein activates microglia: a process leading to disease progression in Parkinson's disease , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[16] C. Haass,et al. α-Synuclein Has a High Affinity for Packing Defects in a Bilayer Membrane , 2004, Journal of Biological Chemistry.
[17] R. Kayed,et al. Permeabilization of Lipid Bilayers Is a Common Conformation-dependent Activity of Soluble Amyloid Oligomers in Protein Misfolding Diseases* , 2004, Journal of Biological Chemistry.
[18] P. S. St George-Hyslop,et al. Defective membrane interactions of familial Parkinson's disease mutant A30P α-synuclein , 2002 .
[19] J. Zimmerberg,et al. Bax-type Apoptotic Proteins Porate Pure Lipid Bilayers through a Mechanism Sensitive to Intrinsic Monolayer Curvature* , 2002, The Journal of Biological Chemistry.
[20] P. S. St George-Hyslop,et al. α-Synuclein Membrane Interactions and Lipid Specificity* , 2000, The Journal of Biological Chemistry.
[21] D. Eliezer,et al. A structural and functional role for 11-mer repeats in alpha-synuclein and other exchangeable lipid binding proteins. , 2003, Journal of molecular biology.
[22] S. M. Park,et al. Proteolytic Cleavage of Extracellular Secreted α-Synuclein via Matrix Metalloproteinases* , 2005, Journal of Biological Chemistry.
[23] S. Ludtke,et al. Membrane thinning caused by magainin 2. , 1995, Biochemistry.
[24] Ad Bax,et al. Structure and Dynamics of Micelle-bound Human α-Synuclein* , 2005, Journal of Biological Chemistry.
[25] Olaf S Andersen,et al. Bilayer thickness and membrane protein function: an energetic perspective. , 2007, Annual review of biophysics and biomolecular structure.
[26] S. Zakharov,et al. On the role of lipid in colicin pore formation. , 2004, Biochimica et biophysica acta.
[27] M. Bally,et al. Production of large unilamellar vesicles by a rapid extrusion procedure: characterization of size distribution, trapped volume and ability to maintain a membrane potential. , 1985, Biochimica et biophysica acta.
[28] P. Lansbury,et al. Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease. , 2001, Biochemistry.
[29] M. Tsujimoto,et al. Asymmetric distribution of phospholipids in biomembranes. , 2006, Biological & pharmaceutical bulletin.
[30] A. Jonas,et al. Stabilization of α-Synuclein Secondary Structure upon Binding to Synthetic Membranes* , 1998, The Journal of Biological Chemistry.
[31] Hai Lin,et al. Amyloid ion channels: a common structural link for protein-misfolding disease. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[32] S. Zakharov,et al. Tuning the membrane surface potential for efficient toxin import , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[33] Harvey T. McMahon,et al. Membrane curvature and mechanisms of dynamic cell membrane remodelling , 2005, Nature.
[34] G. Fasman,et al. Computed circular dichroism spectra for the evaluation of protein conformation. , 1969, Biochemistry.
[35] J. Seelig,et al. Calcium binding to mixed phosphatidylglycerol-phosphatidylcholine bilayers as studied by deuterium nuclear magnetic resonance. , 1987, Biochemistry.
[36] Z. Salamon,et al. Membrane-bound state of the colicin E1 channel domain as an extended two-dimensional helical array. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[37] D. Atlas. Functional and physical coupling of voltage‐sensitive calcium channels with exocytotic proteins: ramifications for the secretion mechanism , 2001, Journal of neurochemistry.
[38] A. Schroit,et al. Aminophospholipid asymmetry: A matter of life and death. , 2003, Annual review of physiology.
[39] A. Bax,et al. Comparison of Structure and Dynamics of Micelle-bound Human α-Synuclein and Parkinson Disease Variants* , 2005, Journal of Biological Chemistry.
[40] R. Kayed,et al. Soluble Amyloid Oligomers Increase Bilayer Conductance by Altering Dielectric Structure , 2006, The Journal of general physiology.
[41] P. Lansbury,et al. The impact of the E46K mutation on the properties of alpha-synuclein in its monomeric and oligomeric states. , 2007, Biochemistry.
[42] S J Ludtke,et al. Membrane pores induced by magainin. , 1996, Biochemistry.
[43] K. Matsuzaki. Why and how are peptide-lipid interactions utilized for self-defense? Magainins and tachyplesins as archetypes. , 1999, Biochimica et biophysica acta.
[44] Christian Rosenmund,et al. Molecular mechanisms of active zone function , 2003, Current Opinion in Neurobiology.
[45] S. McLaughlin,et al. Adsorption of divalent cations to bilayer membranes containing phosphatidylserine , 1981, The Journal of general physiology.
[46] P. Lansbury,et al. Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid. , 2000, Biochemistry.
[47] M. Goedert,et al. Binding of α-Synuclein to Brain Vesicles Is Abolished by Familial Parkinson’s Disease Mutation* , 1998, The Journal of Biological Chemistry.
[48] P. Lansbury,et al. Inhibition of fibrillization and accumulation of prefibrillar oligomers in mixtures of human and mouse alpha-synuclein. , 2000, Biochemistry.
[49] W. Webb,et al. Molecular dynamics in living cells observed by fluorescence correlation spectroscopy with one- and two-photon excitation. , 1999, Biophysical journal.