Influence on Accumulation Levels and Subcellular Localization of Prolamins by Fusion with the Functional Peptide in Transgenic Rice Seeds.

[1]  Jianping Wu,et al.  Bioactive Peptides: From Basic Research to Clinical Trials and Commercialization. , 2022, Journal of agricultural and food chemistry.

[2]  F. Takaiwa,et al.  Improvement of production yield and extraction efficacy of recombinant protein by high endosperm-specific expression along with simultaneous suppression of major seed storage proteins. , 2021, Plant science : an international journal of experimental plant biology.

[3]  M. Matsui,et al.  Transgenic rice seeds expressing altered peptide ligands against the M3 muscarinic acetylcholine receptor suppress experimental sialadenitis-like Sjögren’s syndrome , 2020, Modern rheumatology.

[4]  M. Ohta,et al.  OsERdj7 is an ER-resident J-protein involved in ER quality control in rice endosperm. , 2019, Journal of plant physiology.

[5]  J. Lai,et al.  Peptide-Based Vaccines: Current Progress and Future Challenges , 2019, Chemical reviews.

[6]  F. Takaiwa,et al.  Compensatory rebalancing of rice prolamins by production of recombinant prolamin/bioactive peptide fusion proteins within ER-derived protein bodies , 2018, Plant Cell Reports.

[7]  Taiji Kawakatsu,et al.  An overview on the strategies to exploit rice endosperm as production platform for biopharmaceuticals. , 2017, Plant science : an international journal of experimental plant biology.

[8]  I. Matsumoto,et al.  Suppression of glucose-6-phosphate-isomerase induced arthritis by oral administration of transgenic rice seeds expressing altered peptide ligands of glucose-6-phosphate-isomerase , 2017, Modern rheumatology.

[9]  N. Marmiroli,et al.  Bioactive peptides in plant-derived foodstuffs. , 2016, Journal of proteomics.

[10]  E. Pedrazzini,et al.  Where do Protein Bodies of Cereal Seeds Come From? , 2016, Front. Plant Sci..

[11]  T. Masumura,et al.  Control of foreign polypeptide localization in specific layers of protein body type I in rice seed , 2016, Plant Cell Reports.

[12]  F. Takaiwa,et al.  Rice seed for delivery of vaccines to gut mucosal immune tissues. , 2015, Plant biotechnology journal.

[13]  M. Matsui,et al.  The Anergy Induction of M3 Muscarinic Acetylcholine Receptor–Reactive CD4+ T Cells Suppresses Experimental Sialadenitis‐like Sjögren's Syndrome , 2015, Arthritis & rheumatology.

[14]  Takayuki Sumida,et al.  Suppression of collagen-induced arthritis by oral administration of transgenic rice seeds expressing altered peptide ligands of type II collagen. , 2014, Plant biotechnology journal.

[15]  E. Herman.  Soybean seed proteome rebalancing , 2014, Front. Plant Sci..

[16]  J. Messing,et al.  Proteome balancing of the maize seed for higher nutritional value , 2014, Front. Plant Sci..

[17]  Hideyuki Takahashi,et al.  Analysis of rice ER-resident J-proteins reveals diversity and functional differentiation of the ER-resident Hsp70 system in plants , 2013, Journal of experimental botany.

[18]  F. Takaiwa,et al.  The use of rice seeds to produce human pharmaceuticals for oral therapy , 2013, Biotechnology journal.

[19]  Hideyuki Takahashi,et al.  Transgenic rice seeds accumulating recombinant hypoallergenic birch pollen allergen Bet v 1 generate giant protein bodies. , 2013, Plant & cell physiology.

[20]  Fumio Takaiwa,et al.  Increasing the production yield of recombinant protein in transgenic seeds by expanding the deposition space within the intracellular compartment , 2013, Bioengineered.

[21]  Hideyuki Takahashi,et al.  Recombinant protein yield in rice seed is enhanced by specific suppression of endogenous seed proteins at the same deposit site. , 2012, Plant biotechnology journal.

[22]  F. Takaiwa,et al.  Expression of OsBiP4 and OsBiP5 is highly correlated with the endoplasmic reticulum stress response in rice , 2012, Planta.

[23]  T. Masumura,et al.  Production of human growth hormone in transgenic rice seeds: co-introduction of RNA interference cassette for suppressing the gene expression of endogenous storage proteins , 2012, Plant Cell Reports.

[24]  A. Depicker,et al.  Non-food/feed seeds as biofactories for the high-yield production of recombinant pharmaceuticals. , 2011, Plant biotechnology journal.

[25]  T. Okita,et al.  A Role for the Cysteine-Rich 10 kDa Prolamin in Protein Body I Formation in Rice , 2011, Plant & cell physiology.

[26]  M. Ogawa,et al.  Distinct Roles of Protein Disulfide Isomerase and P5 Sulfhydryl Oxidoreductases in Multiple Pathways for Oxidation of Structurally Diverse Storage Proteins in Rice[W][OA] , 2011, Plant Cell.

[27]  Taiji Kawakatsu,et al.  Cereal seed storage protein synthesis: fundamental processes for recombinant protein production in cereal grains. , 2010, Plant biotechnology journal.

[28]  H. Yasuda,et al.  Reducing Rice Seed Storage Protein Accumulation Leads to Changes in Nutrient Quality and Storage Organelle Formation1[W][OA] , 2010, Plant Physiology.

[29]  Youko Oono,et al.  Analysis of ER stress in developing rice endosperm accumulating beta-amyloid peptide. , 2010, Plant biotechnology journal.

[30]  S. Hirose,et al.  Rice seed ER-derived protein body as an efficient delivery vehicle for oral tolerogenic peptides , 2010, Peptides.

[31]  O. Lau,et al.  Plant seeds as bioreactors for recombinant protein production. , 2009, Biotechnology advances.

[32]  H. Yasuda,et al.  Overexpression of BiP has inhibitory effects on the accumulation of seed storage proteins in endosperm cells of rice. , 2009, Plant & cell physiology.

[33]  M. Sharma,et al.  Plants as bioreactors: Recent developments and emerging opportunities , 2009, Biotechnology Advances.

[34]  S. Hirose,et al.  Expression of unprocessed glutelin precursor alters polymerization without affecting trafficking and accumulation , 2009, Journal of experimental botany.

[35]  M. Yano,et al.  Characterization of a new rice glutelin gene GluD-1 expressed in the starchy endosperm , 2008, Journal of experimental botany.

[36]  F. Takaiwa,et al.  Biopharming to increase bioactive peptides in rice seed. , 2008, Journal of AOAC International.

[37]  H. Kajiura,et al.  Generation of a transgenic rice seed-based edible vaccine against house dust mite allergy. , 2008, Biochemical and biophysical research communications.

[38]  G. Carpenter,et al.  Regulation of salivary gland function by autonomic nerves , 2007, Autonomic Neuroscience.

[39]  T. Jomori,et al.  The correlation between expression and localization of a foreign gene product in rice endosperm. , 2006, Plant & cell physiology.

[40]  F. Takaiwa,et al.  A transgenic rice seed accumulating an anti‐hypertensive peptide reduces the blood pressure of spontaneously hypertensive rats , 2006, FEBS letters.

[41]  H. Kiyono,et al.  A rice-based edible vaccine expressing multiple T cell epitopes induces oral tolerance for inhibition of Th2-mediated IgE responses. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[42]  N. Nishizawa,et al.  Oral immunotherapy against a pollen allergy using a seed-based peptide vaccine. , 2005, Plant biotechnology journal.

[43]  P. Christou,et al.  Sowing the seeds of success: pharmaceutical proteins from plants. , 2005, Current opinion in biotechnology.

[44]  Hideyuki Takahashi,et al.  A novel vesicle derived directly from endoplasmic reticulum is involved in the transport of vacuolar storage proteins in rice endosperm. , 2005, Plant & cell physiology.

[45]  S. Ito,et al.  Muscarinic acetylcholine receptor autoantibodies in patients with Sjögren’s syndrome , 2004, Annals of the rheumatic diseases.

[46]  Rainer Fischer,et al.  Plant-based production of biopharmaceuticals. , 2004, Current opinion in plant biology.

[47]  F. Takaiwa,et al.  Evaluation of tissue specificity and expression strength of rice seed component gene promoters in transgenic rice. , 2004, Plant biotechnology journal.

[48]  Rainer Fischer,et al.  Molecular farming in plants: host systems and expression technology. , 2003, Trends in biotechnology.

[49]  S. Utsumi,et al.  Foreign gene products can be enhanced by introduction into low storage protein mutants. , 2003, Plant biotechnology journal.

[50]  P. Shewry,et al.  Cereal seed storage proteins: structures, properties and role in grain utilization. , 2002, Journal of experimental botany.

[51]  S. Toki,et al.  Iron fortification of rice seed by the soybean ferritin gene , 1999, Nature Biotechnology.

[52]  H. Kiyono,et al.  RNAi-mediated suppression of endogenous storage proteins leads to a change in localization of overexpressed cholera toxin B-subunit and the allergen protein RAG2 in rice seeds , 2013, Plant Cell Reports.

[53]  Chibuike C. Udenigwe,et al.  Food protein-derived bioactive peptides: production, processing, and potential health benefits. , 2012, Journal of food science.

[54]  P. Allen,et al.  Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology. , 1996, Annual review of immunology.