Large-scale Analyses of Disease Biomarkers and Apremilast Pharmacodynamic Effects
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Matthew E. Stokes | M. Trotter | P. Schafer | D. Eisinger | Jing Ai | Robert Yang | Samuel T. Labrie | I. Medvedeva | M. Stokes
[1] Bing Wang,et al. IL‐16 regulates macrophage polarization as a target gene of mir‐145‐3p , 2019, Molecular immunology.
[2] M. Panteghini,et al. Making new biomarkers a reality: the case of serum human epididymis protein 4 , 2018, Clinical chemistry and laboratory medicine.
[3] F. D’Acquisto,et al. Repetitive Exposure of IL-17 Into the Murine Air Pouch Favors the Recruitment of Inflammatory Monocytes and the Release of IL-16 and TREM-1 in the Inflammatory Fluids , 2018, Front. Immunol..
[4] L. Zerbini,et al. The Dual Role of TAM Receptors in Autoimmune Diseases and Cancer: An Overview , 2018, Cells.
[5] A. Gottlieb,et al. Apremilast in Combination With an Interleukin 17A Inhibitor in the Treatment of Recalcitrant Palmoplantar Psoriasis , 2018, Journal of Psoriasis and Psoriatic Arthritis.
[6] S. Mostafaei,et al. Increased inflammatory responsiveness of peripheral blood mononuclear cells (PBMCs) to in vitro NOD2 ligand stimulation in patients with ankylosing spondylitis , 2018, Immunopharmacology and immunotoxicology.
[7] J. Krueger,et al. Synergistic cytokine effects as apremilast response predictors in patients with psoriasis. , 2018, The Journal of allergy and clinical immunology.
[8] L. French,et al. Mechanisms Underlying the Clinical Effects of Apremilast for Psoriasis. , 2018, Journal of drugs in dermatology : JDD.
[9] D. Veale,et al. The pathogenesis of psoriatic arthritis , 2018, The Lancet.
[10] M. Dougados,et al. Measurement properties of the ASAS Health Index: results of a global study in patients with axial and peripheral spondyloarthritis , 2018, Annals of the rheumatic diseases.
[11] S. Georgescu,et al. The Pathophysiological Mechanisms and the Quest for Biomarkers in Psoriasis, a Stress-Related Skin Disease , 2018, Disease markers.
[12] D. Cho,et al. Molecular Mechanisms and Management of a Cutaneous Inflammatory Disorder: Psoriasis , 2017, International journal of molecular sciences.
[13] M. Brown,et al. Progress of genome-wide association studies of ankylosing spondylitis , 2017, Clinical & translational immunology.
[14] A. Dattola,et al. The atopic dermatitis blood signature is characterized by increases in inflammatory and cardiovascular risk proteins , 2017, Scientific Reports.
[15] M. Cassatella,et al. Human Neutrophils Produce CCL23 in Response to Various TLR-Agonists and TNFα , 2017, Front. Cell. Infect. Microbiol..
[16] D. Foell,et al. Proinflammatory Cytokine Environments Can Drive Interleukin‐17 Overexpression by γ/δ T Cells in Systemic Juvenile Idiopathic Arthritis , 2017, Arthritis & rheumatology.
[17] Jia Li,et al. Therapeutic effects of human adipose tissue-derived stem cell (hADSC) transplantation on experimental autoimmune encephalomyelitis (EAE) mice , 2017, Scientific Reports.
[18] G. Hong,et al. Growth Arrest-Specific 6 Enhances the Suppressive Function of CD4+CD25+ Regulatory T Cells Mainly through Axl Receptor , 2017, Mediators of inflammation.
[19] Michael F. Ochs,et al. PatternMarkers & GWCoGAPS for novel data-driven biomarkers via whole transcriptome NMF , 2016, bioRxiv.
[20] D. Gladman,et al. Brief Report: CXCL10 Is a Possible Biomarker for the Development of Psoriatic Arthritis Among Patients With Psoriasis , 2016, Arthritis & rheumatology.
[21] A. Chhabra,et al. Ankylosing Spondylitis and Axial Spondyloarthritis. , 2016, The New England journal of medicine.
[22] C. Selmi,et al. Biomarkers in psoriatic arthritis: a systematic literature review , 2016, Expert review of clinical immunology.
[23] G. Girolomoni,et al. Efficacy and safety of apremilast, an oral phosphodiesterase 4 inhibitor, in patients with moderate‐to‐severe plaque psoriasis over 52 weeks: a phase III, randomized controlled trial (ESTEEM 2) , 2015, The British journal of dermatology.
[24] J. O'dell,et al. The ongoing quest for biomarkers in Ankylosing Spondylitis , 2015, International journal of rheumatic diseases.
[25] P. Barnes,et al. Effect of JAK Inhibitors on Release of CXCL9, CXCL10 and CXCL11 from Human Airway Epithelial Cells , 2015, PloS one.
[26] G. Chodorowska,et al. The Assessment of Selected Bone and Cartilage Biomarkers in Psoriatic Patients from Poland , 2015, Mediators of inflammation.
[27] Peng-Yu Chen,et al. The Pharmacodynamic Impact of Apremilast, an Oral Phosphodiesterase 4 Inhibitor, on Circulating Levels of Inflammatory Biomarkers in Patients with Psoriatic Arthritis: Substudy Results from a Phase III, Randomized, Placebo-Controlled Trial (PALACE 1) , 2015, Journal of immunology research.
[28] Raphael Gottardo,et al. Orchestrating high-throughput genomic analysis with Bioconductor , 2015, Nature Methods.
[29] Matthew E. Ritchie,et al. limma powers differential expression analyses for RNA-sequencing and microarray studies , 2015, Nucleic acids research.
[30] Jilly F. Evans,et al. Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity. , 2014, Cellular signalling.
[31] D. Gladman,et al. Treatment of psoriatic arthritis in a phase 3 randomised, placebo-controlled trial with apremilast, an oral phosphodiesterase 4 inhibitor , 2014, Annals of the rheumatic diseases.
[32] Hee-Jin Kim,et al. Erythropoietin modulates the immune-inflammatory response of a SOD1G93A transgenic mouse model of amyotrophic lateral sclerosis (ALS) , 2014, Neuroscience Letters.
[33] J. Ho,et al. Interferon-gamma inducible protein-10 as a potential biomarker in localized scleroderma , 2013, Arthritis Research & Therapy.
[34] L. Skov,et al. Plasma YKL‐40: a potential biomarker for psoriatic arthritis? , 2013, Journal of the European Academy of Dermatology and Venereology : JEADV.
[35] P. Schafer. Apremilast mechanism of action and application to psoriasis and psoriatic arthritis. , 2012, Biochemical pharmacology.
[36] V. Chandran,et al. Update on Biomarkers in Psoriatic Arthritis: A Report from the GRAPPA 2010 Annual Meeting , 2012, The Journal of Rheumatology.
[37] H. Kaplan,et al. Retinal Self-Antigen Induces a Predominantly Th1 Effector Response in Axl and Mertk Double-Knockout Mice , 2011, The Journal of Immunology.
[38] David R. Willé,et al. Macrolide antibiotics broadly and distinctively inhibit cytokine and chemokine production by COPD sputum cells in vitro. , 2011, Pharmacological research.
[39] W. Liao,et al. Which Psoriasis Patients Develop Psoriatic Arthritis? , 2010, Psoriasis forum.
[40] Jie Ding,et al. CoGAPS: an R/C++ package to identify patterns and biological process activity in transcriptomic data , 2010, Bioinform..
[41] Trevor Hastie,et al. Regularization Paths for Generalized Linear Models via Coordinate Descent. , 2010, Journal of statistical software.
[42] Lei Wu,et al. Apremilast, a cAMP phosphodiesterase‐4 inhibitor, demonstrates anti‐inflammatory activity in vitro and in a model of psoriasis , 2010, British journal of pharmacology.
[43] R. Flavell,et al. Regulating human Th17 cells via differential expression of IL-1 receptor. , 2010, Blood.
[44] J. Kelly,et al. Identification of secreted proteins regulated by cAMP in glioblastoma cells using glycopeptide capture and label‐free quantification , 2009, Proteomics.
[45] K. Wittkowski,et al. Identification of Cellular Pathways of “Type 1,” Th17 T Cells, and TNF- and Inducible Nitric Oxide Synthase-Producing Dendritic Cells in Autoimmune Inflammation through Pharmacogenomic Study of Cyclosporine A in Psoriasis1 , 2008, The Journal of Immunology.
[46] W. Alkema,et al. Literature-based compound profiling: application to toxicogenomics. , 2007, Pharmacogenomics.
[47] E. Diamandis,et al. Human tissue kallikrein expression in the stratum corneum and serum of atopic dermatitis patients , 2007, Experimental dermatology.
[48] S.E. Chang,et al. Neuropeptides and their receptors in psoriatic skin in relation to pruritus , 2007, The British journal of dermatology.
[49] C. Günther,et al. CCL23 Expression Is Induced by IL-4 in a STAT6-Dependent Fashion , 2007, The Journal of Immunology.
[50] B. Nakken,et al. Circulating cytokines in Norwegian patients with psoriatic arthritis determined by a multiplex cytokine array system. , 2007, Rheumatology.
[51] Guoli Wang,et al. LS-NMF: A modified non-negative matrix factorization algorithm utilizing uncertainty estimates , 2006, BMC Bioinformatics.
[52] U. Holmskov,et al. Surfactant protein D in atopic dermatitis and psoriasis , 2006, Experimental dermatology.
[53] Cees G. M. Snoek,et al. Variable Selection , 2019, Model-Based Clustering and Classification for Data Science.
[54] D. Gladman,et al. Psoriatic arthritis: epidemiology, clinical features, course, and outcome , 2005, Annals of the rheumatic diseases.
[55] H. Williams,et al. Genetic association between an AACC insertion in the 3'UTR of the stratum corneum chymotryptic enzyme gene and atopic dermatitis. , 2004, The Journal of investigative dermatology.
[56] A. Ziegler,et al. Ankylosing spondylitis: a β2m–deposition disease? , 2003 .
[57] T. Egelrud,et al. Stratum corneum chymotryptic enzyme in psoriasis , 1999, Archives of Dermatological Research.
[58] J. Prins,et al. The IL-1 system in psoriatic skin: IL-1 antagonist sphere of influence in lesional psoriatic epidermis. , 1997, Journal of immunology.
[59] P. Higgins,et al. P023 CROHN’S DISEASE AND ULCERATIVE COLITIS PATIENT PERSPECTIVES ON PARTICIPATION IN IBD CLINICAL TRIALS , 2018 .
[60] A. Stubhaug,et al. Skin pain and discomfort in psoriasis: an exploratory study of symptom prevalence and characteristics. , 2010, Acta dermato-venereologica.
[61] E. Ferrannini,et al. High values of Th1 (CXCL10) and Th2 (CCL2) chemokines in patients with psoriatic arthtritis. , 2009, Clinical and experimental rheumatology.
[62] A. Ziegler,et al. Ankylosing spondylitis: a b 2 m-deposition disease? , 2003 .
[63] Alex E. Lash,et al. Gene Expression Omnibus: NCBI gene expression and hybridization array data repository , 2002, Nucleic Acids Res..
[64] T. Ittel,et al. Serum osteocalcin levels in patients with psoriatic arthritis: an extended report , 2000, Rheumatology International.
[65] V. Wright,et al. Psoriatic arthritis. , 1983, Clinics in rheumatic diseases.