Comprehensive management of severe intestinal bleeding in a patient supported for 94 days by the biventricular Levitronix CentriMag system.

The use of short-term mechanical circulatory support during postcardiotomy acute heart failure provides an opportunity to stabilize the patient's hemodynamic state while determining the best long-term strategy. Because all of these devices require anticoagulation treatment of various intensities, management of major bleeding can be critical for the overall outcome of the therapy. In this regard, the newest generation of magnetically levitated centrifugal-flow pumps affords several potential advantages in terms of thrombogenicity and eventual discontinuation of anticoagulation treatment. We report the use of a short-term biventricular assist device (Levitronix CentriMag) for 94 days in a 55-year-old man with refractory ventricular arrhythmias after combined heart surgery. Despite serious complications while the patient was on the assist device, including severe intestinal bleeding with the necessity of discontinuing anticoagulation for 10 days and, ultimately, hemicolectomy, the circulatory support was completed with successful heart transplantation.

[1]  N. Yonan,et al.  Early experience with the Levitronix Centrimag device for extra-corporeal membrane oxygenation following lung transplantation. , 2008, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[2]  J. Pepper,et al.  Bridge to decision using the Levitronix CentriMag short-term ventricular assist device. , 2008, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

[3]  L. Miller,et al.  Experience with the Levitronix CentriMag circulatory support system as a bridge to decision in patients with refractory acute cardiogenic shock and multisystem organ failure. , 2007, The Journal of thoracic and cardiovascular surgery.

[4]  A. el-Banayosy,et al.  Prolonged transcutaneous cardiopulmonary support for postcardiotomy cardiogenic shock. , 2007, ASAIO journal.

[5]  J. Pepper,et al.  Clinical performance with the Levitronix Centrimag short-term ventricular assist device. , 2006, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

[6]  R. Favaloro,et al.  Adequate systemic perfusion maintained by a CentriMag during acute heart failure. , 2008, Texas Heart Institute journal.

[7]  W. Cohn,et al.  CentriMag left ventricular assist system: cannulation through a right minithoracotomy. , 2008, Texas Heart Institute Journal.