The Role of Antifibrinolytics in Reducing Blood Loss During Craniofacial or Orthognathic Surgical Procedures: A Meta-Analysis.

[1]  R. Schutgens,et al.  Antifibrinolytic therapy for preventing oral bleeding in patients with haemophilia or Von Willebrand disease undergoing minor oral surgery or dental extractions. , 2019, The Cochrane database of systematic reviews.

[2]  W. Moschetti,et al.  Pharmacologic Hemostatic Agents in Total Joint Arthroplasty-A Cost-Effectiveness Analysis. , 2018, The Journal of arthroplasty.

[3]  Qi Wang,et al.  Tranexamic acid versus aminocaproic acid for blood management after total knee and total hip arthroplasty: A systematic review and meta-analysis. , 2018, International journal of surgery.

[4]  Yanhua Wang,et al.  Efficacy and safety of oral tranexamic acid in total knee arthroplasty , 2018, Medicine.

[5]  B. Apipan,et al.  The effect of different dosage regimens of tranexamic acid on blood loss in bimaxillary osteotomy: a randomized, double-blind, placebo-controlled study. , 2017, International journal of oral and maxillofacial surgery.

[6]  Davinder J Singh,et al.  Craniosynostosis Surgery and the Impact of Tranexamic Acid Dosing , 2017, The Journal of craniofacial surgery.

[7]  J. Sidelmann,et al.  The Effect of Tranexamic Acid and Gender on Intraoperative Bleeding in Orthognathic Surgery-A Randomized Controlled Trial. , 2017, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[8]  E. Akbaş,et al.  Does intravenous tranexamic acid reduce blood loss during surgically assisted rapid palatal expansion? , 2017, Journal of Istanbul University Faculty of Dentistry.

[9]  Xin-long Ma,et al.  Comparison of oral versus intravenous application of tranexamic acid in total knee and hip arthroplasty: A systematic review and meta-analysis. , 2017, International journal of surgery.

[10]  B. Andrews,et al.  Reducing Postoperative Bleeding After Craniosynostosis Repair Utilizing a Low-Dose Transexamic Acid Infusion Protocol , 2017, The Journal of craniofacial surgery.

[11]  M. Ghavimi,et al.  Efficacy of tranexamic acid on side effects of rhinoplasty: A randomized double-blind study. , 2017, Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery.

[12]  H. Schöchl,et al.  Tranexamic acid for treatment and prophylaxis of bleeding and hyperfibrinolysis , 2017, Wiener klinische Wochenschrift.

[13]  Victoria D. Vuong,et al.  Association of Intraoperative Blood Transfusions on Postoperative Complications, 30-Day Readmission Rates, and 1-Year Patient-Reported Outcomes , 2017, Spine.

[14]  D. Zurakowski,et al.  Safety of antifibrinolytics in cranial vault reconstructive surgery: a report from the pediatric craniofacial collaborative group , 2017, Paediatric anaesthesia.

[15]  Joshua C. Demke,et al.  Blood loss and transfusion requirements with epsilon-aminocaproic acid use during cranial vault reconstruction surgery. , 2017, Journal of clinical anesthesia.

[16]  J. Wisoff,et al.  1547: EFFECT OF TRANEXAMIC ACID ON PERIOPERATIVE TRANSFUSION PRACTICES IN CRANIOSYNOSTOSIS REPAIR , 2016, Critical care medicine.

[17]  S. Woolf,et al.  Safety, Efficacy, and Cost-effectiveness of Tranexamic Acid in Orthopedic Surgery. , 2016, Orthopedics.

[18]  G. Glass,et al.  The Efficacy and Safety of Tranexamic Acid in Cranio-Maxillofacial and Plastic Surgery , 2016, The Journal of craniofacial surgery.

[19]  J. A. Taylor,et al.  Aminocaproic acid administration is associated with reduced perioperative blood loss and transfusion in pediatric craniofacial surgery , 2016, Acta anaesthesiologica Scandinavica.

[20]  H. Eftekharian,et al.  The Efficacy of Preoperative Oral Tranexamic Acid on Intraoperative Bleeding During Rhinoplasty , 2016, The Journal of craniofacial surgery.

[21]  S. Afsharinia,et al.  The Effect of Tranexamic Acid on the Blood Loss Volumes in the Patients Underwent Orthognathic Surgeries , 2015 .

[22]  Kant Y K Lin,et al.  Use of tranexamic acid in craniosynostosis surgery , 2015, Plastic surgery.

[23]  N. Saki,et al.  Evaluating the Effect of Intravenous Tranexamic Acid on Intraoperative Bleeding During Elective Rhinoplasty Surgery , 2015 .

[24]  J. Hoffmann,et al.  The value of tranexamic acid during fronto-orbital advancement in isolated metopic craniosynostosis. , 2015, Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery.

[25]  M. Murphy,et al.  The scientific basis for patient blood management. , 2015, Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine.

[26]  Ying Sun,et al.  Epsilon aminocaproic acid reduces blood transfusion and improves the coagulation test after pediatric open-heart surgery: a meta-analysis of 5 clinical trials. , 2015, International journal of clinical and experimental pathology.

[27]  K. Bogusiak,et al.  Analysis of complications after blood components' transfusions. , 2015, Polski przeglad chirurgiczny.

[28]  A. Coppola,et al.  Treatment for preventing bleeding in people with haemophilia or other congenital bleeding disorders undergoing surgery. , 2015, The Cochrane database of systematic reviews.

[29]  D. Royston The current place of aprotinin in the management of bleeding , 2015, Anaesthesia.

[30]  D. Couture,et al.  Evaluating the Safety and Efficacy of Tranexamic Acid Administration in Pediatric Cranial Vault Reconstruction , 2015, The Journal of craniofacial surgery.

[31]  R. Tabrizi,et al.  Effect of tranexamic acid irrigation on perioperative blood loss during orthognathic surgery: a double-blind, randomized controlled clinical trial. , 2015, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[32]  A. Pichard,et al.  Impact of blood transfusions on short- and long-term mortality in patients who underwent transcatheter aortic valve implantation. , 2015, The American journal of cardiology.

[33]  I. Roberts,et al.  Mechanism of action of tranexamic acid in bleeding trauma patients: an exploratory analysis of data from the CRASH-2 trial , 2014, Critical Care.

[34]  D. Hawley,et al.  A systematic review of the effectiveness of intravenous tranexamic acid administration in managing perioperative blood loss in patients undergoing spine surgery. , 2014, Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses.

[35]  V. Narayanan,et al.  Effectiveness of tranexamic acid on intraoperative blood loss in isolated Le Fort I osteotomies--a prospective, triple blinded randomized clinical trial. , 2014, Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery.

[36]  Jiming Liu,et al.  Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range , 2014, BMC Medical Research Methodology.

[37]  T. Haas,et al.  Bleeding management for pediatric craniotomies and craniofacial surgery , 2014, Paediatric anaesthesia.

[38]  S. Goobie,et al.  The Efficacy of Antifibrinolytic Drugs in Children Undergoing Noncardiac Surgery: A Systematic Review of the Literature , 2014, Anesthesia and analgesia.

[39]  S. Berkowitz,et al.  Allogeneic blood transfusions and postoperative infections after total hip or knee arthroplasty. , 2014, The Journal of bone and joint surgery. American volume.

[40]  M. Zestos,et al.  Aprotinin and transfusion requirements in pediatric craniofacial surgery , 2014, Paediatric anaesthesia.

[41]  S. Goobie Should Aprotinin be reconsidered for use in pediatric surgery? , 2014, Paediatric anaesthesia.

[42]  A. Székely,et al.  Antifibrinolytics , 2014, Heart, lung and vessels.

[43]  C. Marzola,et al.  Intraoperative blood loss and blood transfusion requirements in patients undergoing orthognathic surgery , 2014, Oral and Maxillofacial Surgery.

[44]  M. Pagnano,et al.  Economic impact of tranexamic acid in healthy patients undergoing primary total hip and knee arthroplasty. , 2013, The Journal of arthroplasty.

[45]  Songsong Zhu,et al.  The effect of tranexamic acid on blood loss in orthognathic surgery: a meta-analysis of randomized controlled trials. , 2013, Oral surgery, oral medicine, oral pathology and oral radiology.

[46]  A. Hapfelmeier,et al.  Replacement of aprotinin by ε-aminocaproic acid in infants undergoing cardiac surgery: consequences for blood loss and outcome. , 2013, British journal of anaesthesia.

[47]  R. Krishnan,et al.  Evaluation of the efficacy of tranexamic acid on blood loss in orthognathic surgery. A prospective, randomized clinical study. , 2012, International journal of oral and maxillofacial surgery.

[48]  K. Goa,et al.  Tranexamic Acid , 1999, Drugs.

[49]  A. Karimi,et al.  Efficacy of tranexamic acid on blood loss during bimaxilary osteotomy: A randomized double blind clinical trial , 2012, Saudi journal of anaesthesia.

[50]  S. Salisbury,et al.  Comparative Analysis of Tranexamic Acid Use in Minimally Invasive Versus Open Craniosynostosis Procedures , 2011, The Journal of craniofacial surgery.

[51]  J. Meara,et al.  Efficacy of Tranexamic Acid in Pediatric Craniosynostosis Surgery: A Double-blind, Placebo-controlled Trial , 2011, Anesthesiology.

[52]  X. Capdevila,et al.  Intraoperative Tranexamic Acid Reduces Blood Transfusion in Children Undergoing Craniosynostosis Surgery: A Randomized Double-blind Study , 2011, Anesthesiology.

[53]  S. Gangemi,et al.  Hypersensitivity to tranexamic acid: a wide spectrum of adverse reactions , 2010, Pharmacy World & Science.

[54]  D. Moher,et al.  Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement , 2009, BMJ : British Medical Journal.

[55]  R. Marcus,et al.  Predictors of Blood Loss in Fronto-Orbital Advancement and Remodeling , 2009, The Journal of craniofacial surgery.

[56]  F. Chung,et al.  Topical application of antifibrinolytic drugs for on-pump cardiac surgery: a systematic review and meta-analysis , 2009, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

[57]  M. Irwin,et al.  The effect of tranexamic acid on blood loss during orthognathic surgery: a randomized controlled trial. , 2008, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[58]  Raghu Kacker,et al.  Random-effects model for meta-analysis of clinical trials: an update. , 2007, Contemporary clinical trials.

[59]  L. Rasmusson,et al.  Evaluation of hemorrhage depressors on blood loss during orthognathic surgery: a retrospective study. , 2004, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[60]  F. Carceller,et al.  [Usefulness of tranexamic acid in cranial remodeling surgery]. , 2003, Revista espanola de anestesiologia y reanimacion.

[61]  D. Altman,et al.  Measuring inconsistency in meta-analyses , 2003, BMJ : British Medical Journal.

[62]  K. Slim,et al.  Methodological index for non‐randomized studies (MINORS): development and validation of a new instrument , 2003, ANZ journal of surgery.

[63]  K. Muraszko,et al.  Efficacy of aprotinin in children undergoing craniofacial surgery. , 2003, Journal of neurosurgery.

[64]  K. Chow,et al.  Multifocal myoclonus secondary to tranexamic acid , 2003, Journal of neurology, neurosurgery, and psychiatry.

[65]  W. Sieghart,et al.  Tranexamic acid, a widely used antifibrinolytic agent, causes convulsions by a gamma-aminobutyric acid(A) receptor antagonistic effect. , 2002, The Journal of pharmacology and experimental therapeutics.

[66]  A. Stewart,et al.  Aprotinin reduces blood loss and the need for transfusion in orthognathic surgery. , 2001, The British journal of oral & maxillofacial surgery.

[67]  M. Harris,et al.  Oral Surgery: The effect of tranexamic acid (cyclokapron) on blood loss after third molar extraction under a day case general anaesthetic , 1999, British Dental Journal.

[68]  A R Jadad,et al.  Assessing the quality of reports of randomized clinical trials: is blinding necessary? , 1996, Controlled clinical trials.

[69]  J. Lewis,et al.  EFFECTS OF EPSILON AMINOCAPROIC ACID ON COAGULATION AND FIBRINOLYTIC MECHANISMS. , 1964, Journal of the American Medical Association (JAMA).