Early Experiences with Crowdsourcing Airway Annotations in Chest CT

Measuring airways in chest computed tomography (CT) images is important for characterizing diseases such as cystic fibrosis, yet very time-consuming to perform manually. Machine learning algorithms offer an alternative, but need large sets of annotated data to perform well. We investigate whether crowdsourcing can be used to gather airway annotations which can serve directly for measuring the airways, or as training data for the algorithms. We generate image slices at known locations of airways and request untrained crowd workers to outline the airway lumen and airway wall. Our results show that the workers are able to interpret the images, but that the instructions are too complex, leading to many unusable annotations. After excluding unusable annotations, quantitative results show medium to high correlations with expert measurements of the airways. Based on this positive experience, we describe a number of further research directions and provide insight into the challenges of crowdsourcing in medical images from the perspective of first-time users.

[1]  Marleen de Bruijne,et al.  Vessel-guided airway tree segmentation: A voxel classification approach , 2010, Medical Image Anal..

[2]  Peter D Sly,et al.  Assessment of early bronchiectasis in young children with cystic fibrosis is dependent on lung volume. , 2013, Chest.

[3]  Lena Maier-Hein,et al.  Crowdsourcing for Reference Correspondence Generation in Endoscopic Images , 2014, MICCAI.

[4]  Keno März,et al.  Crowdtruth validation: a new paradigm for validating algorithms that rely on image correspondences , 2015, International Journal of Computer Assisted Radiology and Surgery.

[5]  Joseph E. Burns,et al.  Note: This Copy Is for Your Personal Non-commercial Use Only. to Order Presentation-ready Copies for Distribution to Your Colleagues or Clients, Contact Us at Www.rsna.org/rsnarights. Distributed Human Intelligence for Colonic Polyp Classification in Computer-aided Detection for Ct Colonography 1 , 2022 .

[6]  Nassir Navab,et al.  AggNet: Deep Learning From Crowds for Mitosis Detection in Breast Cancer Histology Images , 2016, IEEE Trans. Medical Imaging.

[7]  Jenny Chen,et al.  Opportunities for Crowdsourcing Research on Amazon Mechanical Turk , 2011 .

[8]  Marleen de Bruijne,et al.  Optimal surface segmentation using flow lines to quantify airway abnormalities in chronic obstructive pulmonary disease , 2014, Medical Image Anal..

[9]  Tunde Peto,et al.  Crowdsourcing as a Screening Tool to Detect Clinical Features of Glaucomatous Optic Neuropathy from Digital Photography , 2015, PloS one.

[10]  Wieying Kuo,et al.  Assessment of bronchiectasis in children with cystic fibrosis by comparing airway and artery dimensions to normal controls on inspiratory and expiratory spirometer guided chest computed tomography , 2015 .

[11]  Scott H. Donaldson,et al.  Cystic fibrosis lung disease starts in the small airways: Can we treat it more effectively? , 2010, Pediatric pulmonology.