The European Bioinformatics Institute web site: a new view

SUMMARY The European Bioinformatics Institute (EBI), and outstation of the European Molecular Biology laboratory, has revamped its web site for the second time since 1997 in order to address increased user demand as well as establishing better uniformity and easier accessibility for the ever growing number of users and services it offers to the community. A GRID-like hardware infrastructure has been put in place to provide round the clock services in a redundant and reliable fashion. AVAILABILITY http://www.ebi.ac.uk/

[1]  Rolf Apweiler,et al.  The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000 , 2000, Nucleic Acids Res..

[2]  G J Barton,et al.  Computer speed and sequence comparison. , 1992, Science.

[3]  D. Lipman,et al.  Improved tools for biological sequence comparison. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[4]  Rolf Apweiler,et al.  The SWISS-PROT protein sequence data bank and its supplement TrEMBL , 1997, Nucleic Acids Res..

[5]  J. Thompson,et al.  DbClustal: rapid and reliable global multiple alignments of protein sequences detected by database searches. , 2000, Nucleic acids research.

[6]  S F Altschul,et al.  Local alignment statistics. , 1996, Methods in enzymology.

[7]  J. Thompson,et al.  CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. , 1994, Nucleic acids research.

[8]  Rodrigo Lopez,et al.  The EMBL Nucleotide Sequence Database , 1999, Nucleic Acids Res..

[9]  C. Sander,et al.  Protein structure comparison by alignment of distance matrices. , 1993, Journal of molecular biology.

[10]  Thomas L. Madden,et al.  Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. , 1997, Nucleic acids research.

[11]  Rolf Apweiler,et al.  InterProScan - an integration platform for the signature-recognition methods in InterPro , 2001, Bioinform..

[12]  Chris Sander,et al.  MView: a web-compatible database search or multiple alignment viewer , 1998, Bioinform..

[13]  Alex Bateman,et al.  The InterPro database, an integrated documentation resource for protein families, domains and functional sites , 2001, Nucleic Acids Res..