A system-based study of the variation in the amplitude of the compound sensory nerve action potential recorded using surface electrodes.

This study arose from the impression that there is a wide variation in the amplitude of the compound sensory nerve action potential (SNAP) when recorded using surface electrodes. Both the physiological factors influencing the SNAP and the method of measurement itself can be viewed as inputs to a system that produces the recorded value as its output. Taking a systems approach to the analysis of the variation in the recorded value of the SNAP on repeat testing, the techniques of statistical process control and experimental design were used to study three electrodes. All showed wide variation of the results in a single control subject. Many different factors were studied but no single factor was found to be the cause for a significant amount of the variation. This finding, coupled to the wide variation demonstrated, has implications for the use of surface recording of the SNAP.

[1]  D F Stegeman,et al.  Modelling compound action potentials of peripheral nerves in situ. I. Model description: evidence for a non-linear relation between fibre diameter and velocity. , 1982, Electroencephalography and clinical neurophysiology.

[2]  Fritz Buchthal,et al.  Evoked action potentials and conduction velocity in human sensory nerves , 1966 .

[3]  R. LorentedeNo.  Analysis of the distribution of the action currents of nerve in volume conductors. , 1947 .

[4]  Lloyd S. Nelson,et al.  Column: Technical Aids: The Shewhart Control Chart--Tests for Special Causes , 1984 .

[5]  A. Lang,et al.  Dual influence of temperature on compound nerve action potential , 1981, Journal of the Neurological Sciences.

[6]  G. Dawson,et al.  THE RECORDING OF NERVE ACTION POTENTIALS THROUGH SKIN IN MAN , 1949, Journal of neurology, neurosurgery, and psychiatry.

[7]  W. Edwards Deming,et al.  Out of the Crisis , 1982 .

[8]  J. S. Hunter,et al.  Statistics for Experimenters: An Introduction to Design, Data Analysis, and Model Building. , 1979 .

[9]  Roger W. Berger,et al.  Guide to Quality Control , 1982 .

[10]  E. Denys.  AAEM minimonograph #14: The influence of temperature in clinical neurophysiology , 1991, Muscle & nerve.

[11]  R. Plackett,et al.  THE DESIGN OF OPTIMUM MULTIFACTORIAL EXPERIMENTS , 1946 .

[12]  Annabeth L. Propst.  Understanding industrial experimentation , 1988 .

[13]  C. Bolton.  Electrophysiologic changes in uremic neuropathy after successful renal transplantation , 1976, Neurology.

[14]  F. Buchthal,et al.  Sensory potentials in polyneuropathy. , 1971, Brain : a journal of neurology.

[15]  J. Glass,et al.  Inter‐ and intra‐examiner reliability of nerve conduction measurements in normal subjects , 1991, Annals of neurology.

[16]  Donald J. Wheeler,et al.  Understanding Statistical Process Control , 1986 .

[17]  H. Hughes.  ASTM Manual on Quality Control of Materials. , 1952 .

[18]  F. Beyeler,et al.  Temperature dependence of normal sensory nerve action potentials , 1977, Journal of Neurology.

[19]  H. Strenge,et al.  Correlation of electrophysiological and quantitative histological findings in the sural nerve of man , 1977, Journal of Neurology.

[20]  C. Bolton,et al.  Human sensory nerve compound action potential amplitude: variation with sex and finger circumference. , 1980, Journal of neurology, neurosurgery, and psychiatry.

[21]  D F Stegeman,et al.  Models and analysis of compound nerve action potentials. , 1991, Critical reviews in biomedical engineering.

[22]  F. Buchthal,et al.  Sensory action potentials and biopsy of the sural nerve in neuropathy. , 1978, Brain : a journal of neurology.

[23]  W S Pease,et al.  Electronic Filter Effects on Normal Motor and Sensory Nerve Conduction Tests , 1990, American journal of physical medicine & rehabilitation.

[24]  R. Gilliatt.  Sensory conduction studies in the early recognition of nerve disorders , 1978, Muscle & nerve.

[25]  M. Mcquillen,et al.  Serial ulnar nerve conduction velocity measurements in normal subjects. , 1969, Journal of neurology, neurosurgery, and psychiatry.

[26]  J. Michael Brick.  Evaluating the Measurement Process , 1989 .

[27]  J.G. Webster,et al.  The mosaic electrical characteristics of the skin , 1993, IEEE Transactions on Biomedical Engineering.

[28]  A. Bleasel,et al.  Variability of repeated nerve conduction studies. , 1991, Electroencephalography and clinical neurophysiology.

[29]  C. Bolton,et al.  The effects of temperature on human compound action potentials. , 1981, Journal of neurology, neurosurgery, and psychiatry.

[30]  B. Katirji.  Clinical Electromyography, 2nd Ed. , 1995, Neurology.